[1]臧业峰 朱卫洁 赵希春 周垂宝.自体富血小板血浆联合关节镜下保留残端重建术治疗前交叉韧带损伤的临床研究[J].中国中医骨伤科杂志,2019,27(09):25-28.
　ZANG Yefeng ZHU Weijie ZHAO Xichun ZHOU Chuibao.Clinical Study of PRP Combined with Arthroscopic ACL Reconstruction with Remnant Preservation in Treatment of Anterior Cruciate Ligament Injury[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2019,27(09):25-28.
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自体富血小板血浆联合关节镜下保留残端重建术治疗前交叉韧带损伤的临床研究()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第27卷
期数:
2019年09期
页码:
25-28
栏目:
临床研究
出版日期:
2019-09-08

文章信息/Info

Title:
Clinical Study of PRP Combined with Arthroscopic ACL Reconstruction with Remnant Preservation in Treatment of Anterior Cruciate Ligament Injury
文章编号:
1005-0205(2019)09-0025-04
作者:
臧业峰1 朱卫洁1 赵希春1 周垂宝1
1山东青岛市胶州中心医院关节创伤外科 (山东 青岛,266300)
Author(s):
ZANG Yefeng1 ZHU Weijie1 ZHAO Xichun1 ZHOU Chuibao1
1Joint Trauma Surgery,Jiaozhou Central Hospital of Qingdao City,Qingdao 266300,Shandong China.
关键词:
自体富血小板血浆;  保残重建术;  前交叉韧带;  腱骨愈合
Keywords:
platelet-rich plasma(PRP);  reconstruction with remnant preservation;  anterior cruciate ligament(ACL);  tendon-bone healing
分类号:
R686.5
文献标志码:
A
摘要:
目的:探讨自体富血小板血浆(PRP)联合关节镜下保留残端前交叉韧带(ACL)重建术治疗前交叉韧带损伤对早期腱骨愈合的影响及安全性。方法:选取本院2014年5月至2017年9月收治的112例前交叉韧带损伤患者为研究对象,按照随机数表法将之分为对照组、观察组; 对照组采用关节镜下保残重建术治疗,观察组采用PRP联合保残重建术治疗,对比两组患者治疗前后关节功能恢复水平,骨隧道恢复程度以及安全性等。结果:术前两组患者Lysholm以及KT-1000评分差异无统计学意义(P>0.05); 术后两组患者Lysholm以及KT-1000评分随时间延长而升高,观察组患者在各时间点Lysholm以及KT-1000评分均明显高于对照组,差异有统计学意义(P<0.05)。观察组患者术后各时间点胫骨隧道恢复程度明显大于对照组,差异有统计学意义(P<0.05); 观察组术后12个月IKDC优良率明显高于对照组,差异有统计学意义(P<0.05)。两组患者治疗及随访期并未出现相关并发症。结论:运用PRP联合关节镜下保留残端ACL重建术可更大程度促进患者腱骨的早期愈合,促进患者关节功能恢复,安全性高。
Abstract:
Objective:To investigate the effect of platelet-rich plasma(PRP)combined with arthroscopic anterior cruciate ligament(ACL)reconstruction with remnant preservation in treatment of Anterior cruciate ligament injury on early tendon-bone healing and safety.Methods:112 cases of knee ACL rupture treated in our hospital from May 2014 to September 2017 were selected and randomly divided into observation group and control group,with 25 cases in each group.The control group received the arthroscopic ACL reconstruction with remnant preservation,while the observation group received the PRP combined with arthroscopic ACL reconstruction with remnant preservation.Then the recovery of joint function and bone tunnel and safety were compared between the two groups.Results:Lysholm and KT-1000 scores had no difference between the two groups before operation(P>0.05),which were increased in both groups after operation,and were higher in the observation group than in the control group(P<0.05).The recovery degree of tibial tunnel in the observation group was significantly higher than that in the control group at each time point after operation(P<0.05); the excellent and good rate of IKDC in the observation group was significantly higher than that in the control group at the postoperative 12 months(P>0.05).There were no complications during the treatment and follow-up period in both groups.Conclusion:PRP combined with arthroscopic ACL reconstruction can promote early healing of tendons and bones in patients and improve the recovery of joint function with high safety.

参考文献/References:

[1] 胡培兴,李瑾,郑慷,等.关节镜下ACL重建术保留残端纤维对膝关节功能的影响分析[J].中国中医骨伤科杂志,2015,22(7):23-25. [2] 何川,李彦林,李晓刚,等.前交叉韧带保留残端重建术对膝关节本体感觉功能恢复的疗效分析[J].中国修复重建外科杂志,2014,27(4):442-447. [3] GUO L,CHEN H,LUO J M,et al.An arthroscopic second-look study on the effect of remnant preservation on synovialization of bone-patellar tendon-bone allograft in anterior cruciate ligament reconstruction[J].Journal of Arthroscopic & Related Surgery,2016,32(5):868-877. [4] 姚楚亮,陈少文,杨焱鑫,等.关节镜下清除和保留断裂前交叉韧带残端重建术后疗效对比[J].中华全科医学,2015,13(4):425-426. [5] 左金增,史福东.关节镜下腓骨长肌腱保留残端重建前交叉韧带的临床研究[J].中国医药,2016,11(10):1530-1534. [6] 中华中医药学会.膝关节交叉韧带损伤[J].风湿病与关节炎,2013,2(5):78-80. [7] 林志达.Kujala和Lysholm量表评估膝关节前交叉韧带术后功能信度及其相关性研究[J].按摩与康复医学,2015,30(5):42-44. [8] 齐勇,樊粤光,孙鸿涛.关节镜下内减张技术重建膝关节前交叉韧带的临床研究[J].中国修复重建外科杂志,2016,29(2):138-142. [9] 谢凯罗,董伊隆,张力成.前交叉韧带单束解剖重建术股骨隧道定位的X线评估[J].中医正骨,2015,30(10):11-14. [10] 秦豪,李晓,谭海涛,等.富含血小板血浆对前交叉韧带重建后腱骨愈合的影响[J].广西医科大学学报,2017,34(4):555-558. [11] 胡喜春,黄长明,范华强,等.关节镜下前交叉韧带重建中保留残端对膝关节功能及本体感觉恢复的影响研究[J].现代生物医学进展,2017,17(26):2436-2437. [12] 张磊,李智尧,刘劲松,等.关节镜下保留胫骨残端纤维同种异体肌腱移植重建前交叉韧带[J].中国骨伤,2013,26(5):370-375. [13] 黄媛霞,段永壮,陶金刚,等.关节镜下保留残端与非保残重建前交叉韧带的疗效比较[J].中国临床解剖学杂志,2017,34(5):564-566. [14] PAN W,DAN L,WEI Y,et al.Tendon-to-bone healing using an injectable calcium phosphate cement combined with bone xenograft/BMP composite[J].Biomaterials,2013,34(38):9926-9936. [15] 李洋,徐斌,徐洪港,等.兔自体富血小板血浆对兔ACL重建后腱骨愈合的影响[J].安徽医科大学学报,2016,51(9):1277-1280. [16] 张振君,贺明,白伦浩.关节镜下异体腘绳肌腱保留残端重建前交叉韧带的近期疗效[J].中国骨与关节杂志,2017,6(9):665-668.

备注/Memo

备注/Memo:
基金项目:青岛市医药科研指导计划项目(2017-WJZD097)(收稿日期:2019-02-09)
更新日期/Last Update: 2019-09-08