[1]周海洋 周宇 王睿△ 卞恒杰 周飞 王中兴 康新桂.高血糖中老年患者左股骨近端骨密度研究[J].中国中医骨伤科杂志,2019,27(09):29-32.
　ZHOU Haiyang ZHOU Yu WANG Rui BIAN Hengjie ZHOU Fei WANG Zhongxing KANG Xingui.A Study on the Changes of Bone Mineral Density in the Left Proximal Femur in Middle-aged and Elderly Patients with Hyperglycemia[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2019,27(09):29-32.
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高血糖中老年患者左股骨近端骨密度研究()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第27卷
期数:
2019年09期
页码:
29-32
栏目:
临床研究
出版日期:
2019-09-08

文章信息/Info

Title:
A Study on the Changes of Bone Mineral Density in the Left Proximal Femur in Middle-aged and Elderly Patients with Hyperglycemia
文章编号:
1005-0205(2019)09-0029-04
作者:
周海洋1 周宇1 王睿1△ 卞恒杰1 周飞1 王中兴1 康新桂1
1南京中医药大学附属南京市中西医结合医院(南京,210014)
Author(s):
ZHOU Haiyang1 ZHOU Yu1 WANG Rui1△ BIAN Hengjie1 ZHOU Fei1 WANG Zhongxing1 KANG Xingui1
1Nanjing Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Nanjing University of Traditional Chinese Medicine,Nanjing 210014,China.
关键词:
高血糖;  左股骨近端;  骨密度;  骨质疏松
Keywords:
hyperglycemia;  left proximal femur;  bone mineral density;  osteoporosis
分类号:
R681.8
文献标志码:
A
摘要:
目的:研究高血糖中老年患者左股骨颈近端骨密度及部分实验指标的变化规律,为骨质疏松的防治提供新的科学依据。方法:收集双能X线骨密度仪测定的188例左股骨颈近端骨密度及部分实验指标资料,选取相近血糖正常的人群作对照组,进行分类比较。结果:高血糖组患者的左股骨近端(TROCH,INTER,NECK,WARD及HTOT)的骨密度均低于对照组,两组及两组同性别组间差异有统计学意义(P<0.05),其中Ward三角区的骨密度最低,Inter区的骨密度最高。高血糖组、对照组及两组同性别间的比较,HbAlc,FPG,TG,TC及h-CRP均高于对照组,差异有统计学意义(P<0.05),IGF-1较对照组略低,差异无统计学意义(P>0.05)。骨密度与IGF1正相关,与FPG,TG,TC及h-CRP负相关。结论:高血糖中老年患者骨密度降低明显,骨质流失严重,更容易发生骨质疏松,应该进行早期干预及治疗,降低老年骨折发生率。
Abstract:
Objective:To study the changes of bone mineral density and some experimental indexes of left femoral neck in middle-aged and elderly patients with hyperglycemia,and to provide a new scientific basis for the prevention and treatment of osteoporosis.Methods:The bone mineral density(BMD)of the left femoral neck and some experimental indexes were measured by dual energy X-ray absorptiometry.The normal subjects with normal blood glucose were selected as the control group,and classified and compared between the 188 cases.Results:The bone mineral density of proximal left femur(TROCH,INTER,NECK,WARD,HTOT)in hyperglycemia group was lower than that in control group.There was a significant difference between the two groups and the same sex group(P<0.05).The bone mineral density of Ward triangle was the lowest and that of interzone was the highest.The levels of HbAlc,FPG,TG,TC and h-CRP in hyperglycemia group,control group and two groups were higher than those in normal control group(P<0.05),and the levels of IGF-1 were slightly lower than those in control group(P>0.05).Bone mineral density was positively correlated with IGF1 and negatively correlated with FPG,TG,TC and h-CRP. Conclusion:The decrease of bone mineral density in middle-aged and elderly patients with hyperglycemia may lead to osteoporosis.Clinicians should give adequate attention to early prevention.

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备注/Memo

备注/Memo:
△通信作者 E-mail:wangrui_217@hotmail.com(收稿日期:2019-02-12)
更新日期/Last Update: 2019-09-08