[1]孟魏魏 葛京化△ 龚政.骨密冲水煎剂治疗绝经后骨质疏松症的临床观察[J].中国中医骨伤科杂志,2019,27(04):19-22.
　MENG Weiwei GE Jinghua GONG Zheng.Clinical Observation of Gumichong Granule Water Decoction in the Treatment of Postmenopausal Osteoporosis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2019,27(04):19-22.
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骨密冲水煎剂治疗绝经后骨质疏松症的临床观察()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第27卷
期数:
2019年04期
页码:
19-22
栏目:
临床研究
出版日期:
2019-04-12

文章信息/Info

Title:
Clinical Observation of Gumichong Granule Water Decoction in the Treatment of Postmenopausal Osteoporosis
文章编号:
1005-0205(2019)04-0019-04
作者:
孟魏魏1 葛京化1△ 龚政1
1上海市长宁区天山中医医院(上海,200051)
Author(s):
MENG Weiwei1 GE Jinghua1△ GONG Zheng1
1Shanghai Changning Tianshan Traditional Chinese Medicine Hospital,Shanghai 200051,China.
关键词:
骨密冲水煎剂;  绝经后骨质疏松;  中医证候分值;  生活质量
Keywords:
decoction of Gumichong;  postmenopausal osteoporosis;  traditional Chinese medicine symptom score;  quality of life
分类号:
R274.39
文献标志码:
A
摘要:
目的:观察骨密冲水煎剂治疗肝肾阴虚型绝经后骨质疏松症的有效性、安全性。方法:选取绝经后骨质疏松(肝肾阴虚型)患者80例,随机分为2组,对照组40例,观察组40例。两组均给予每天400 mL鲜牛奶饮用,观察组加用骨密冲水煎剂治疗; 疗程均为6个月,观察组服药结束后每天继续饮用400 mL鲜牛奶,两组进行1年随访。观察两组患者在治疗前后及随访结束时的中医症候积分、生存质量、不良反应情况。结果:1)中医症候积分观察组明显优于对照组(P<0.05); 其中观察组对腰背酸痛的改善效果明显,差异有统计学意义(P<0.05),随访1年时,观察组对腰背酸痛等症候的改善仍然有效,差异有统计学意义(P<0.05)。2)中医症候疗效对比,观察组疗效优于对照组,差异有统计学意义(P<0.05)。3)治疗前后两组患者在躯体疼痛(BP)、活力(VT)、生理功能(PF)、总体健康(GH)、精神健康(MH)、社会功能(SF)等方面与治疗前比较,差异有统计学意义(P<0.05),尤其是在躯体疼痛和活力的改善方面。4)治疗前后,两组治疗不良反应比较差异无统计学意义(P>0.05)。结论:在绝经后骨质疏松症(肝肾阴虚型)患者中给予骨密冲水煎剂可缓解腰背部疼痛感,并明显提高患者生存质量,临床效果显著。
Abstract:
Objective:To observe the clinical effect of gumichong decoction on postmenopausal osteoporosis(Deficiency of Yin of both Liver and Kidney).Methods:80 cases of postmenopausal osteoporosis(liver-kidney Yin deficiency)were randomly divided into 2 groups, 40 cases in the control group and 40 cases in the observation group.Both groups were given 400 mL fresh milk to drink every day, and the observation group was treated with gumichong decoction.The course of treatment was 6 months.The observation group continued to drink 400 mL of fresh milk every day after the end of medication, and the two groups were followed up for one year.To observe and compare the improvement of TCM symptom scores and quality of life of the two groups before and after treatment and after follow-up.Results:1)The observation group was significantly better than the control group in improving TCM syndrome score(P<0.05); Among them, the observation group had a significant effect on the improvement of lumbar and back pain(P<0.05).After 1 year of follow-up, the observation group had a longer effect on the symptoms of traditional Chinese medicine.2)By comparing the curative effect of TCM symptoms, it was found that the curative effect of the observation group was better than that of the control group(P<0.05).3)There were significant differences between the two groups before and after treatment in physical pain(BP), vitality(VT), physiological function(PF), general health(GH), mental health(MH), and social function(SF), especially in the improvement of physical pain and vitality(P<0.05).4)Before and after treatment, there was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion:In postmenopausal osteoporosis patients, the administration of bone dense scour decoction can relieve the sense of low back pain, and significantly improve the quality of life of patients, clinical effect is significant, worthy of clinical application and promotion.

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备注/Memo

备注/Memo:
基金项目:上海市长宁区科委课题(ZY3-FWMS-1-1001) 上海市长宁区天山中医医院重点专科项目 (2017ZDZK-01) △通信作者 E-mail:gjh2091@hotmail.com
更新日期/Last Update: 2019-04-12