[1]张斌青 张国庆 刘玉珂 秦晓飞 郭会利.原发性骨淋巴瘤影像学表现与病理特征[J].中国中医骨伤科杂志,2019,27(04):23-27.
　ZHANG Binqing ZHANG Guoqing LIU Yuke QIN Xiaofei GUO Huili.Pathological Features and Imaging Analysis of Primary Bone Lymphoma[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2019,27(04):23-27.
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原发性骨淋巴瘤影像学表现与病理特征()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第27卷
期数:
2019年04期
页码:
23-27
栏目:
临床研究
出版日期:
2019-04-12

文章信息/Info

Title:
Pathological Features and Imaging Analysis of Primary Bone Lymphoma
文章编号:
1005-0205(2019)04-0023-05
作者:
张斌青1 张国庆1 刘玉珂1 秦晓飞1 郭会利1
1河南洛阳正骨医院(河南省骨科医院)(河南 洛阳,471002)
Author(s):
ZHANG Binqing1 ZHANG Guoqing1 LIU Yuke1 QIN Xiaofei1 GUO Huili1
1Luoyang Orthopedic Hospital of Henan Province(Orthopedic Hospital of Henan Province), Luoyang 471002, Henan China.
关键词:
淋巴瘤;  骨肿瘤;  影像学;  病理学;  诊断
Keywords:
lymphoma;  bone tumors;  imaging;  pathology;  diagnosis
分类号:
R738.1
文献标志码:
A
摘要:
目的:探讨总结原发性骨淋巴瘤的影像学表现及病理特征,以提高其诊断准确性。方法:回顾性分析2012年1月至2017年12月经病理证实的21例原发性骨淋巴瘤患者的X线片,CT,MRI及SPECT的影像学资料,仔细复习其影像学征象并与病理特征作参照。结果:21例患者,单发18例,多发3例。单发18例中,椎骨6例,股骨4例,肱骨及髂骨各2例,肋骨、腓骨、尺骨、肩胛骨各1例。多发3例中,多节段椎骨1例,累及椎骨、髂骨1例,累及下颌骨、股骨、胫骨、左腕骨及双足跗骨1例。X线和CT显示溶骨型19例,混合型2例,病理骨折11例,有明显的软组织肿块11例。MRI检查9例,信号均匀7例,信号不均匀2例; 病灶T1WI呈等信号或稍低信号,T2WI呈稍高信号2例、高信号7例。MRI增强扫描7例,肿瘤不均匀强化3例,均匀强化4例。SPECT显像8例,病灶均表现为核素异常浓聚。病理类型均为弥漫性非霍奇金淋巴瘤,其中B细胞19例,T细胞2例。结论:原发性骨淋巴瘤可发生于全身骨骼各个部位,有一定影像学特征,综合应用多种影像学检查可增加病变显示的信息量,但最终确诊仍需要病理学检查。
Abstract:
Objective:To summarize the imaging and pathological features of primary bone lymphoma(PBL), in order to improve its diagnostic accuracy.Methods:The imaging data of 21 cases with PBL confirmed by pathology were retrospectively analyzed and compared with corresponding pathological results.Results:Of these 21 cases, single bone involved in 18 cases and multiple bones involved in 3 cases.Of these 18 cases, 6 cases involved in vertebrae, 4 cases of femurs, 2 cases of humerus and iliums respectively, 1 case of ulnar, rib, tibia and scapular respectively.Of these 3 cases, 1 cases involved in vertebrae, 1 case vertebrae and ilium,1 case mandible, femur, tibia, left carpal bone and bilateral tarsal.X-ray and CT showed osteolytic destruction type in 19 cases, mixed destruction type in 2 cases, pathological fracture in 11 cases, obvious soft tissue mass in 11 cases.MRI examination in 9 cases showed homogeneous signal in 7 cases, heterogeneous signal in 2 cases, isointense signal on T1WI in 2 cases, high signal on T2WI in 7 cases.Enhanced scanning in 7 cases, 3 cases of tumor showed nonuniform enhanced, 4 cases uniform enhanced.SPECT imaging in 8 cases, the cases showed abnormal concentration of nuclides.Pathological types were diffuse non-Hodgkin's lymphoma, including 19 cases of B cells, 2 cases of T cells.Conclusion:PBL can occur in all parts of the body skeleton, imaging features have some characteristics, comprehensive application of a variety of imaging can fully display the disease, but the final diagnosis still requires pathological examination.

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更新日期/Last Update: 2019-04-12