[1]何海军 王荣田 陈卫衡△ 李泰贤 陈志伟 刘道兵 谢斌 王均玉.健脾通络方治疗发作期髋骨关节炎的临床研究[J].中国中医骨伤科杂志,2017,25(01):9-13.
　HE Haijun WANG Rongtian CHEN Weiheng LI Taixian CHEN Zhiwei LIU Daobing XIE Bin WANG Junyu.Clinical Research on Jianpitongluo Formula in the Treatment of Hip Arthritis in Attack Stage[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2017,25(01):9-13.
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健脾通络方治疗发作期髋骨关节炎的临床研究()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第25卷
期数:
2017年01期
页码:
9-13
栏目:
临床研究
出版日期:
2017-01-15

文章信息/Info

Title:
Clinical Research on Jianpitongluo Formula in the Treatment of Hip Arthritis in Attack Stage
文章编号:
1005-0205(2017)01-0009-05
作者:
何海军1 王荣田1 陈卫衡1△ 李泰贤1 陈志伟1 刘道兵1 谢斌1 王均玉1
1中国中医科学院望京医院(北京,100102)
Author(s):
HE Haijun1 WANG Rongtian1 CHEN Weiheng1△ LI Taixian1 CHEN Zhiwei1 LIU Daobing1 XIE Bin1 WANG Junyu1
1Wangjing Hospital of China Academy of Chinese Medical Sciences,Beijing 100102,China.
关键词:
健脾通络方;  髋骨关节炎;  发作期;  临床研究
Keywords:
Jianpitongluo formula;  hip arthritis;  attack stage;  clinical research
分类号:
R684.3
文献标志码:
A
摘要:
目的:通过观察健脾通络方治疗发作期髋骨关节炎的疗效,为发作期髋骨关节炎的治疗提供一种有效的方法。方法:采用随机对照的设计方案,将2012年10月至2015年1月于中国中医科学院望京医院骨关节三科因髋骨关节炎住院治疗的患者120例,随机分为对照组和治疗组,每组各60例。对照组采用关节腔冲洗联合注射玻璃酸钠,治疗组采用健脾通络方联合关节腔冲洗及关节腔玻璃酸钠治疗。对患者分别在治疗后1个月和6个月进行疗效随访,脱落5例,其中治疗组3例,对照组2例。以VAS疼痛评分、Harris评分及髋关节积液作为疗效评价指标,数据统计运用SPSS16.0统计软件,组内比较采用配对t检验,组间计数资料比较采用χ2检验,计量资料比较采用t检验。结果:治疗组和对照组治疗后VAS评分均低于治疗前,差异有统计学意义(P＜0.001),治疗后1个月、6个月治疗组均低于对照组,差异有统计学意义(P＜0.001,P＜0.05)。治疗组和对照组治疗后Harris评分均高于治疗前,差异有统计学意义(P＜0.001),治疗后1个月、6个月治疗组均高于对照组,差异有统计学意义(P＜0.001),优良率两组均为100%.治疗组和对照组治疗后关节积液均少于治疗前,差异有统计学意义(P＜0.001),治疗后1个月、6个月治疗组均显著低于对照组,差异有统计学意义(P＜0.001),且治疗后1个月、6个月关节积液小于5 mm者比例高于对照组(P＜0.05,P＜0.001)。结论:健脾通络方联合关节腔冲洗可以有效缓解发作期髋骨关节炎患者疼痛症状,改善关节功能,延缓病情发展,是一种简单、有效、可行的髋骨关节炎保髋治疗方法,值得推广。
Abstract:
Objective:To observe the effect of Jianpitongluo formula in the treatment of hip arthritis in the attack stage,and to provide an effective method for treating hip arthritis in the attack stage.Methods:Randomized controlled design was used.From October 2012 to January 2015,in the third department of orthopedic in Wangjing hospital of China academy of Chinese medical sciences,120 cases of hospitalized patients with hip osteoarthritis were randomly divided into control group and treatment group,60 cases in each group.The control group was taken joint cavity flushing combined with sodium hyaluronate injection.And the treatment group was taken Jianpitongluo formula combined with joint cavity flushing and intra-articular sodium hyaluronate injection.The patients were followed up for 1 month to 6 months after treatment respectively.There were 5 cases fell off,3 in treatment group and 2 in control group.The VAS pain score,Harris score and hip effusion were used as the curative effect evaluation index.The data were analyzed with SPSS16.0 software.Paired t test was used to compare the data in groups,the χ2 test was used to compare the data between groups,and the t test was used to compare the measurement data.Results:The VAS score in both treatment group and control group after treatment were lower than that of before treatment(P＜0.001).The VAS score in the treatment group at 1 month and 6 months after treatment were lower than the control group(P＜0.001,P＜0.05).Harris score in both treatment group and control group after treatment were higher than that of before treatment(P＜0.001).Harris score in the treatment group at 1 month and 6 months after treatment were higher than the control group(P＜0.001,P＜0.05).The good rate was 100% for both groups.After treatment,joint effusion in both two groups were less than that of before treatment(P＜0.001).Joint effusion in the treatment group was significant lower than that of control group at 1 month and 6 months after treatment(P＜0.001).And the proportion of joint effusion less than 5 mm in the treatment group was higher than that of the control group at 1 month and 6 months after treatment(P＜0.05,P＜0.001).Conclusion:Jianpitongluo formula combined with joint cavity flushing can alleviate the pain of the patient with hip arthritis in the attack stage effectively,improve joint function,and delay the progression of the disease.It is a simple,effective and feasible hip salvage method for treating hip osteoarthritis,and it is worth for promoting.

参考文献/References:

[1] 陈卫衡.膝骨关节炎中医诊疗专家共识(2015年)[J].中医正骨,2015,27(7):4-5.
[2] 中华医学会骨科学分会.骨关节炎诊治指南(2007年版)[J].中华骨科杂志,2007,27(10):793-796.
[3] 国家食品药品监督管理局.中药新药临床研究指导原则(试行)[M] 北京:中国医药科技出版社,2002:351.
[4] Lawrence JS.Rheumatism in population[M].London:Wiliam Heinemann MedBooks LTD,1997:153.
[5] Harris WH.Arthritis of the hip after dislocation and acetabular fracture:treatment by mold arthroplasty:an end-result study using a new method of result evaluation[J].J Bone Joint Surg Am,1969,51(4):737-755.
[6] Weiss PF,Arabshahi B,Johnson A,et al.High prevalence oftemporomandibular joint arthritis at disease onset in children withjuvenile idiopathic arthritis,as detected by magnetic resonance imagingbut not by ultrasound[J].Arthritis Rheum,2008,58(4):1189-1196.
[7] 刘玉杰,李众利,王志刚,等.关节镜在诊断和治疗髋关节疾患中的应用[J].中华外科杂志,2002,40(12):912-915.
[8] Kotlarz H,Gunnarsson CL,Fang H,et al.Insurer and out-of-pocket costs of osteoarthritis in the US:evidence from national survey data[J].Arthritis Rheum,2009,60(12):3546-3553.
[9] 朱军璇,王敏智,刘彪,等.活络效灵丹加减方治疗骨性关节炎的药效研究[J].中国中医基础医学杂志,2012,18(4):389-391.
[10] 周红梅,金亮,吴斌,等.独活寄生汤治疗骨关节炎疗效的Meta分析[J].中国中医急症,2015,24(12):2099-2102.
[11] 郭跃,杨青梅,鲁超,等.膝骨性关节炎的中医证候特点研究[J].中医临床研究,2015,7(4):1-4.
[12] 万晓旭,王均玉,周宇,等.健脾通络方治疗膝关节骨性关节炎临床观察[J].中医临床研究,2013,5(5):7-10.
[13] 何海军,王荣田,陈志伟,等.关节腔冲洗联合注射玻璃酸钠治疗髋骨关节炎的临床研究[J].中国中医骨伤科杂志,2016,24(2):9-13.
[14] 李龑,刘道兵,何海军,等.中西医结合治疗髋关节骨性关节炎临床研究[J].中医临床研究,2014,6(8):6-9.
[15] 陈卫衡,于海洋,邹海鹏,等.玻璃酸钠治疗髋关节疾病的临床疗效研究[J].中国骨与关节损伤杂志,2010,25(4):322-323.

备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81373801) 北京市自然科学基金资助项目(7142170) △通信作者 E-mail:drchenweiheng@163.com
更新日期/Last Update: 2017-01-15