[1]徐凯捷 欧阳桂林△ 肖涟波 聂智兴 韩大鹏 姚捷.加味桃红四物汤联合那曲肝素钙预防单侧膝关节置换术后深静脉血栓的疗效观察[J].中国中医骨伤科杂志,2022,30(04):21-24.
　XU Kaijie OUYANG Guilin XIAO Lianbo NIE Zhixing HAN Dapeng YAO Jie.Efficacy of Jiawei Taohong Siwu Decoction Combined with Nadroparin Calcium in Preventing Deep Vein Thrombosis after Total Knee Arthroplasty[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2022,30(04):21-24.
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加味桃红四物汤联合那曲肝素钙预防单侧膝关节置换术后深静脉血栓的疗效观察()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第30卷
期数:
2022年04期
页码:
21-24
栏目:
临床研究
出版日期:
2022-04-15

文章信息/Info

Title:
Efficacy of Jiawei Taohong Siwu Decoction Combined with Nadroparin Calcium in Preventing Deep Vein Thrombosis after Total Knee Arthroplasty
文章编号:
1005-0205(2022)04-0021-04
作者:
徐凯捷1; 2 欧阳桂林1△ 肖涟波1 聂智兴1 韩大鹏1 姚捷1
1上海中医药大学附属光华医院(上海,200052)2上海市嘉定区中医医院
Author(s):
XU Kaijie1; 2 OUYANG Guilin1△ XIAO Lianbo1 NIE Zhixing1 HAN Dapeng1 YAO Jie1
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200052,China; 2Jiading Hospital of Traditional Chinese Medicine,Shanghai 201800,China.
关键词:
桃红四物汤; 那曲肝素钙; 深静脉血栓; 膝骨关节炎; 膝关节置换术
Keywords:
Taohong Siwu decoction;  nadroparin calcium;  deep vein thrombosis;  knee osteoarthritis;  total knee replacement
分类号:
R543.6
文献标志码:
A
摘要:
目的:观察加味桃红四物汤联合那曲肝素钙预防膝关节置换术后深静脉血栓的临床疗效。方法:将2019年1月至2020年6月收治的96例行单侧全膝关节置换手术的膝骨关节炎患者,随机分为中西联合组、方药组和西药组,每组32例。方药组术后第1天开始口服加味桃红四物汤,西药组术后第1天开始注射那曲肝素钙,中西联合组术后口服加味桃红四物汤联合注射那曲肝素钙。3组均观察治疗2周,比较3组术后深静脉血栓(DVT)形成情况,术后D-二聚体、血红蛋白、视觉模拟疼痛评分(VAS)、运动范围(ROM)、膝关节功能评分(HSS)、血瘀证候积分等。结果:术后2周中西联合组D-二聚体值低于西药组和方药组(P<0.05),术后1周中西联合组血瘀症状明显轻于西药组和方药组(P<0.05),术后1周中西联合组、方药组贫血改善优于西药组(P<0.05),术后2周中西联合组VAS疼痛评分明显轻于西药组和方药组(P<0.05)。3组术后ROM活动度较术前明显改善,3组术后HSS功能评分明显优于术前(P<0.05)。结论:加味桃红四物汤与那曲肝素钙联合治疗能改善膝关节置换术后临床症状,预防DVT效果好,利于术后康复。
Abstract:
Objective:To observe the clinical efficacy of Jiawei Taohong Siwu decoction combined with nadroparin calcium in preventing deep vein thrombosis after knee arthroplasty.Methods:96 patients with knee osteoarthritis from January 2019 to June 2020 underwent total knee arthroplasty and were randomly divided into Chinese and western combined group,prescription group and western medicine group,with 32 cases in each group.Jiawei Taohong Siwu decoction was started to take in the prescription group on the first day after the operation; the Nadroparin calcium was started to inject in the western medicine group on the first day after the operation,and the Jiawei Taohong Siwu decoction combined with the injection of nadroparin calcium was taken in the Chinese and western combination group after the operation.The three groups were observed and treated for 2 weeks,and the deep vein thrombosis,D-dimer,hemoglobin,VAS,ROM,HSS,blood stasis syndrome scores and so on were compared among the three groups.Results:The D-dimer value of the Chinese-western combined group was lower than that of the western medicine group and the prescription group 2 weeks after the operation(P<0.05),and the blood stasis symptoms in the Chinese-western combined group were lighter than that of the western medicine group and the prescription group 1 week after the operation(P<0.05).The improvement of anemia in the Chinese-western combined group and the prescription group was better than that of the western medicine group in the last 1 week(P<0.05),and the VAS pain score in the Chinese-western combined group was lighter than the western medicine group and the prescription group 2 weeks after the operation(P<0.05).The postoperative ROM activity of the three groups was better than the preoperative ROM activity.The postoperative HSS was better than the preoperative HSS in the three groups(P<0.05).Conclusion:The combined treatment of Jiawei Taohong Siwu decoction,and nadroparin calcium can effectively improve the clinical symptoms after knee arthroplasty.And it can effectively prevent DVT and facilitate postoperative recovery.

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备注/Memo

备注/Memo:
基金项目:上海市十三五重点专科-中西医结合骨关节病科(shslczdzk04801)上海市长宁区卫生和健康委员会科研项目(20191003)
△通信作者 E-mail:oyglmd@hotmail.com
更新日期/Last Update: 1900-01-01