[1]曾俊 李春根△ 柳根哲 陈超 祝永刚 赵思浩 郭雨霞.术前关节突关节退变与颈椎前路杂合手术后异位骨化形成的相关性研究[J].中国中医骨伤科杂志,2021,29(12):37-42.
 ZENG Jun LI Chungen LIU Genzhe CHEN Chao.Study on the Correlation between Facet Joint Degeneration and Heterotopic Ossification after Anterior Cervical Hybrid Operation[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2021,29(12):37-42.
点击复制

术前关节突关节退变与颈椎前路杂合手术后异位骨化形成的相关性研究()
分享到:

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第29卷
期数:
2021年12期
页码:
37-42
栏目:
临床研究
出版日期:
2021-12-15

文章信息/Info

Title:
Study on the Correlation between Facet Joint Degeneration and Heterotopic Ossification after Anterior Cervical Hybrid Operation
文章编号:
1005-0205(2021)12-0037-06
作者:
曾俊1 李春根2△ 柳根哲2 陈超2 祝永刚2 赵思浩2 郭雨霞1
Author(s):
ZENG Jun1 LI Chungen2△ LIU Genzhe2 CHEN Chao2
1Beijing University of Chinese Medicine,Beijing 100029,China; 2Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University,Beijing 100010,China.
关键词:
颈椎病 杂合手术 异位骨化 关节突关节退变
Keywords:
spondylopathy hybrid surgery heterotopic ossification facet joint degeneration
分类号:
R681.
文献标志码:
A
摘要:
目的:分析术前关节突关节的退变与前路杂合术后异位骨化形成的相关性。方法:纳入2017年7月至2019年12月行颈椎前路杂合手术的患者72例,收集患者术前、术后3个月、6个月、12个月、末次随访的VAS评分、JOA评分、NDI评分及Odom’s评分,总体评价神经功能和临床症状改善情况。测量术前及末次随访时置换节段活动度,关节突关节退变采用Park标准分级,异位骨化采用McAfee标准分级。进行相关系数检验,明确二者有无相关性。结果:72例患者随访时间为12~36个月,平均(23.0±3.8)个月。末次随访时,16例发生异位骨化患者中,7例发生退变(Ⅰ度2例,Ⅱ度2例,Ⅲ度3例),退变率43.75%; 56例未发生异位骨化患者中,9例术前发生关节突关节退变(Ⅰ级5例,Ⅱ级4例),退变率16.07%; 两者比较差异有统计学意义(χ2=4.98,P=0.026)。关节突关节术前退变与术后异位骨化形成正相关(r=0.683,P=0.033)。结论:颈椎前路杂合术前关节突关节退变和末次随访时异位骨化的发生正相关,关节突关节术前退变程度越高,术后产生异位骨化的概率及分级也越高。
Abstract:
Objective:To explore the relationship between the degree of degeneration of the facet joints before operation and the formation of heterotopic ossification after the anterior hybrid operation of the cervical spine.Methods:72 patients underwent anterior hybrid surgery were included from July 2017 to December 2019.VAS score,JOA score,NDI score and Odom’s score of patients before operation,3,6,12 and 24 months after operation were selected to evaluate postoperative clinical symptoms and neurological improvement.The segmental range of motion was measured before surgery and at the last follow-up; the Park grading standard was used to classify the degree of degeneration of the facet joints before the operation,and the McAfee standard was used to classify the heterotopic ossification at the last follow-up.Correlation coefficient test were performed to clarify the correlation between them.Results:The follow-up time of 72 patients ranged from 12 to 36 months(23.0±3.8).All patients underwent anterior cervical hybrid surgery.At the last follow-up,there were 7 patients had degeneration(2 cases of grade Ⅰ,2 cases of grade Ⅱ,3 cases of grade Ⅲ)in 16 patients with heterotopic ossification,and the degeneration rate was 43.75%.Among the 56 patients without heterotopic ossification,9 patients had facet joint degeneration(grade Ⅰ in 5 cases,grade Ⅱ in 4 cases),and the degeneration rate was 16.07%.The difference was statistically significant(χ2=4.98,P=0.026).Preoperative degeneration of facet joint was positively correlated with postoperative heterotopic ossification(r=0.683,P=0.033).Conclusion:There is a positive correlation between heterotopic ossification and facet joint degeneration at the last follow-up.The higher the degree of degeneration of facet joint before operation,the higher the probability and grade of heterotopic ossification after operation.

参考文献/References:

[1] 谢兴文,王春晓,李宁.颈椎病发病特征与影响因素的流行病学调查[J].中国中医骨伤科杂志,2012,20(7):46-47.
[2] MILLER J,SASSO R,ANDERSON P,et al.Adjacent level degeneration:bryan total disc arthroplasty versus anterior cervical discectomy and fusion[J].Clin Spine Surg,2018,31(2):E98-E101.
[3] 齐英娜,李春根,柳根哲,等.颈椎前路混杂手术治疗颈椎退行性疾病35例[J].中国中医骨伤科杂志,2020,28(1):52-56.
[4] 李广州,刘浩,陈华,等.单节段人工颈椎间盘置换术后异位骨化对相邻节段影响的临床观察[J].中华医学杂志,2020,100(1):26-31.
[5] 赵学千,李晋玉,刘楚吟,等.双节段人工颈椎间盘置换术治疗颈椎病后颈椎矢状位参数的变化研究[J].中国中医骨伤科杂志,2020,28(12):21-25.
[6] POINTILLART V,CASTELAIN J E,COUDERT P,et al.Outcomes of the Bryan cervical disc replacement:fifteen year follow-up[J].International Orthopaedics,2018,42(4):851-857.
[7] 田伟,阎凯,韩骁,等.Bryan人工间盘置换与前路减压融合治疗颈椎退行性疾病的中期随访研究[J].中华骨科杂志,2013,33(2):97-104.
[8] QI M,CHEN H,CAO P,et al.Incidence and risk factors analysis of heterotopic ossification after cervical disc replacement[J].Chin Med J(Engl),2014,127(22):3871-3875.
[9] 周智毅,王建伟,张亚峰,等.关节突关节退变与腰椎不稳症关系的研究进展[J].中国中医骨伤科杂志,2018,26(7):81-83.
[10] 杨子明,李放,陈华江.颈椎病的分型、诊断及非手术治疗专家共识(2018)[J].中华外科杂志,2018,56(6):401-402.
[11] PARK M S,LEE Y B,MOON S H,et al.Facet joint degeneration of the cervical spine:a computed tomographic analysis of 320 patients[J].Spine(Phila Pa 1976),2014,39(12):713-718.
[12] MCAFEE P C,CUNNINGHAM B W,DEVINE J,et al.Classification of heterotopic ossification in artificial disk replacement[J].J Spinal Disord Tech,2003,16(4):384-389.
[13] POINTILLART V,CASTELAIN J E,COUDERT P A,et al.Outcomes of the Bryan cervical disc replacement:fifteen year follow-up[J].International Orthopaedics,2018,42(4):E759-E763.
[14] NUNLEY P D,CAVANAUGH D A,KERR E J,et al.Heterotopic ossification after cervical total disc replacement at 7 years-prevalence,progression,clinical implications,and risk factors[J].International Journal of Spine Surgery,2018,12(3):352-361.
[15] 董桂贤,刘玉民,张宁.Hybrid手术与颈椎前路融合手术治疗多节段颈椎病的临床比较[J].颈腰痛杂志,2018,39(3):369-370.
[16] 何鹏,杜俊伟,马拓.颈椎前路Hybrid术对脊髓型颈椎病患者颈椎矢状位参数及颈椎功能恢复的影响[J].陕西医学杂志,2020,49(12):1593-1596.
[17] 赵思浩,柳根哲,尹辛成,等.颈椎矢状位序列参数在评估脊髓型颈椎病治疗效果中的临床价值[J].中国医学前沿杂志(电子版),2020,12(3):155-160.
[18] 张先莉,朱利峰.ACCF、ACDF及Hybrid三种手术方案对连续双节段脊髓型颈椎病患者的疗效与安全性比较[J].中国医学前沿杂志(电子版),2018,10(12):104-109.
[19] 姚冀,高杨,周俊杰,等.前路Hybrid减压固定融合术与后路椎板切除固定融合术治疗多节段脊髓型颈椎病的疗效比较[J].中国骨与关节损伤杂志,2020,35(7):722-724.
[20] 齐英娜,李春根,柳根哲,等.颈椎前路Hybrid术治疗颈椎退行性疾病[J].中国骨伤,2021,34(1):80-85.
[21] GELLHORN A C,KATZ J N,SURI P.Osteoarthritis of the spine:the facet joints[J].Nature Reviews Rheumatology,2013,9(4):216-224.
[22] 刘路,王星,康小燕,等.7~12岁儿童颈椎关节突关节的数字化三维形态研究[J].中国组织工程研究,2020,24(6):877-881.
[23] 郭冲,王秋安,孟强,等.成人颈椎关节突关节螺旋CT三维参数的测定[J].中国微创外科杂志,2021,21(2):145-149.

备注/Memo

备注/Memo:
1北京中医药大学(北京,100029)2首都医科大学附属北京中医医院通信作者 E-mail:leechungen@126.com
更新日期/Last Update: 1900-01-01