[1]梅其杰 徐文飞 段戡 叶永生 袁长深郭锦荣 延伟伟 毛德文 姚弘毅△.十一方药酒涂擦结合艾瑞昔布片治疗膝骨关节炎的临床疗效观察[J].中国中医骨伤科杂志,2021,29(10):43-46.
　MEI Qijie XU Wenfei DUAN Kan YE Yongsheng YUAN ChangshenGUO Jinrong YAN Weiwei MAO Dewen YAO Hongyi.Clinical Observation of Shiyifang Medicinal Wine Rubbing Combinewith Imrecoxib Tablets in Treating Knee Osteoarthritis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2021,29(10):43-46.
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十一方药酒涂擦结合艾瑞昔布片治疗膝骨关节炎的临床疗效观察()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第29卷
期数:
2021年10期
页码:
43-46
栏目:
临床论著
出版日期:
2021-10-15

文章信息/Info

Title:
Clinical Observation of Shiyifang Medicinal Wine Rubbing Combinewith Imrecoxib Tablets in Treating Knee Osteoarthritis
文章编号:
1005-0205(2021)10-0043-04
作者:
梅其杰1 徐文飞2 段戡1 叶永生2 袁长深1郭锦荣1 延伟伟2 毛德文1 姚弘毅3△
1广西中医药大学第一附属医院(南宁,530023)2广西中医药大学3华中科技大学同济医学院附属梨园医院
Author(s):
MEI Qijie1 XU Wenfei2 DUAN Kan1 YE Yongsheng2 YUAN Changshen1GUO Jinrong1 YAN Weiwei2 MAO Dewen1 YAO Hongyi3△
1The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning 530023,China; 2Guangxi University of Traditional Chinese Medicine, Nanning 530200,China; 3The Hospital of Liyuan Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430077,China.
关键词:
十一方药酒;  涂擦;  非甾体类抗炎药;  骨关节炎
Keywords:
Shiyifang medicated wine;  inunction;  non-steroidal anti-inflammatory drugs;  osteoarthritis
分类号:
R681.5
文献标志码:
A
摘要:
目的:通过观察十一方药酒涂擦联合艾瑞昔布片治疗膝骨关节炎(KOA)的临床效果,分析其有效性、安全性。方法:纳入100例KOA门诊患者,采取随机数字表法随机分成2组(各50例),A组予十一方药酒涂擦联合艾瑞昔布口服治疗,B组应用艾瑞昔布片口服,观察期为2周,分别于治疗前、治疗后1周、2周3个时段,采用VAS、WOMAC、中医临床症状评分等指标评定疗效。结果:A组有效率为94%,优于B组的86%,差异有统计学意义(P<0.05); 治疗1周、2周后,两组在VAS、WOMAC、中医临床症状评分上均优于治疗前,差异有统计学意义(P<0.05),组间比较提示治疗组(A组)较观察组(B组)好,差异有统计学意义(P<0.05)。结论:十一方药酒联合艾瑞昔布片中西医结合治疗KOA患者,较单纯西药疗法疗效更好,值得临床推广应用。
Abstract:
Objective:To observe and analyze the efficacy and safety of combination of Shiyifang medicinal wine rubbing and imrecoxib tablets in treating knee osteoarthritis(KOA). Methods:A total of 100 patients with KOA were randomly divided into 2 groups with 50 patients in each group by random number table method. Patients in group A were treated with Shiyifang medicinal wine combined with imrecoxib tablets, and patients in group B were treated with imrecoxib tablets. The observation course was 2 weeks. The VAS, WOMAC, TCM clinical symptom score were used to evaluate the therapeutic efficacy before treatment, 1 week and 2 weeks after treatment respectively. Results:The effective rate of group A was 94%, which was better than that in group B(86%)(P<0.05). After 1 week and 2 weeks of treatment, the scores of VAS, WOMAC and TCM clinical symptoms scores in group A and B were better than those before treatment(P<0.05), and the ratio between groups indicated that the scores in group A were better than those in group B(P<0.05). Conclusion:Shiyifang medicinal wine rubbing combined with imrecoxib tablets on the treatment of KOA patients is more significant than western medicine therapy alone, and it is worthy for further clinical promotion.

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备注/Memo

备注/Memo:
基金项目:广西科技重大专项(广西创新驱动发展专项资金项目)
(桂科AA17202036)
△通信作者 E-mail:yaohongyi168@163.com
更新日期/Last Update: 1900-01-01