[1]杨思红 张寅 关英杰 白雪 陈薇△.活血止痛软胶囊治疗骨伤疾病临床疗效分析[J].中国中医骨伤科杂志,2021,29(02):31-36.
　YANG Sihong ZHANG Yin GUAN Yingjie BAI Xue CHEN Wei.Clinical Effect Analysis of Huoxue Zhitong SoftCapsule in the Treatment of Bone Injury[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2021,29(02):31-36.
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活血止痛软胶囊治疗骨伤疾病临床疗效分析()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第29卷
期数:
2021年02期
页码:
31-36
栏目:
文献研究
出版日期:
2021-02-15

文章信息/Info

Title:
Clinical Effect Analysis of Huoxue Zhitong SoftCapsule in the Treatment of Bone Injury
文章编号:
1005-0205(2021)02-0031-06
作者:
杨思红1 张寅2 关英杰1 白雪1 陈薇1△
1北京中医药大学循证医学中心(北京,100029)2首都医科大学附属北京佑安医院
Author(s):
YANG Sihong1 ZHANG Yin2 GUAN Yingjie1 BAI Xue1 CHEN Wei1△
1Centre for Evidence-Based Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China; 2Beijing You’an Hospital,Capital Medical University,Beijing 100069,China.
关键词:
活血止痛软胶囊;  临床研究;  骨伤疾病;  疗效分析
Keywords:
Huoxue Zhitong soft capsule;  clinical research;  bone fracture;  clinical efficacy analysis
分类号:
R274.39
文献标志码:
A
摘要:
目的:综合分析活血止痛软胶囊治疗骨伤疾病的临床研究,了解活血止痛软胶囊治疗骨伤疾病的临床疗效及应用现状,对该药的临床研究提出思考和建议,以期为该药未来的临床研究设计和方向提供参考。方法:通过系统全面检索了国内外的数据库,其中中文数据库为中国知网数据库(CNKI)、万方数据库、重庆维普中文科技期刊数据库(VIP)、中国生物医学文献数据库(CBM),英文数据库为美国国立医学图书馆(PubMed)及Cochrane图书馆,检索时间为各数据库建库至2019年7月。纳入活血止痛软胶囊的临床研究,并对其临床疗效进行相应的分析。结果:共纳入随机对照试验(RCT)10项,临床对照试验(CCT)1项,病例报告1项,队列研究1项。目前活血止痛软胶囊在临床主要应用于软组织损伤、膝关节骨性关节炎、腰腿痛,具有改善疼痛、肿胀及功能障碍的疗效,且未发现肝肾功能及血、尿、便常规异常,无严重不良反应。结论:活血止痛软胶囊主要应用于软组织损伤、膝关节骨性关节炎、腰腿痛疾病的治疗,但是针对该药物开展的临床研究数量仍然较少,应严谨地开展临床试验来提高证据质量,为指导活血止痛软胶囊运用于临床实践提供有力的证据支撑。
Abstract:
Comprehensively analyzed all the clinical studies on the treatment of bone injury diseases with Huoxue Zhitong soft capsule,and understood the clinical efficacy and application status of the treatment of bone injury diseases with Huoxue Zhitong soft capsule,and put forward thoughts and suggestions on the clinical research the drug,so as to provide references for the future clinical research design and direction of the drug.Methods:4 Chinese databases(CNKI,VIP,Wanfang Data,CBM)and 2 English databases(PubMed,Cochrane Library)were retrieved from the establishment of each database to July 2019.The clinical research of Huoxue Zhitong soft capsule was included,and the corresponding clinical efficacy was analyzed.Results:A total of 10 randomized controlled trials(RCTs),1 CCT,1 case report and 1 cohort study were included.At present,Huoxue Zhitong soft capsule were mainly used for soft tissue injury,osteoarthritis of knee joint,pain in low back and legs.It had effect on improving pain,swelling and dysfunction.No abnormalities were found in liver and kidney function,blood,urine or stool routine,and no serious adverse reactions were observed.Conclusion:Huoxue Zhitong soft capsule were mainly used for soft tissue injury,osteoarthritis of knee joint,pain in low back and legs.However,the number of clinical studies on the drug was still small,and clinical trials should be carried out rigorously to improve the quality of evidence and provide strong evidence support for guiding the application of Huoxue Zhitong soft capsule in clinical practice.

参考文献/References:

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备注/Memo

备注/Memo:
△杨思红,张寅为共同第一作者
△通信作者 E-mail:chenweibucm@163.com
更新日期/Last Update: 2021-02-15