[1]张建林 任睿双△.加味益肾强骨汤联合三步推拿点穴手法治疗膝骨性关节炎的临床研究[J].中国中医骨伤科杂志,2018,26(01):34-38.
　ZHANG Jianlin REN Ruishuang.Clinical Study of Modified Yishenqianggu Soup Combined with Three-step Massage in the Treatment of Knee Osteoarthritis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2018,26(01):34-38.
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加味益肾强骨汤联合三步推拿点穴手法治疗膝骨性关节炎的临床研究()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第26卷
期数:
2018年01期
页码:
34-38
栏目:
临床研究
出版日期:
2018-01-15

文章信息/Info

Title:
Clinical Study of Modified Yishenqianggu Soup Combined with Three-step Massage in the Treatment of Knee Osteoarthritis
文章编号:
1005-0205(2018)01-0034-05
作者:
张建林1 任睿双1△
1陕西宝鸡市中医医院骨关节二科(陕西 宝鸡,721000) △通信作者 E-mail:49290051@163.com
Author(s):
ZHANG Jianlin1 REN Ruishuang1
1The Second Department of Joint Surgery, Baoji Traditional Chinese Medicine Hospital, Baoji 721000,Shaanxi China.
关键词:
加味益肾强骨汤;  三步推拿点穴手法;  膝骨性关节炎
Keywords:
Keywords: modified Yishenqianggu soup;  three-step massage;  knee osteoarthritis
分类号:
R684.3
文献标志码:
A
摘要:
目的:探究加味益肾强骨汤联合三步推拿点穴手法对膝骨性关节炎患者的临床效果。方法:选取2015年8月至2017年2月本院82例膝骨性关节炎患者,依据随机数表法分为观察组与对照组,各41例。对照组41例予以玻璃酸钠+三步推拿点穴手法治疗,观察组41例予以加味益肾强骨汤+三步推拿点穴手法治疗。治疗时间为4个疗程,统计观察两组治疗效果及不良反应发生情况,并对比治疗前及疗程结束后两组血清炎性因子[肿瘤坏死因子-α(TNF-α),白细胞介素-6(IL-6)及白细胞介素-1(IL-1)]水平、膝关节活动度、功能评分变化情况。结果:观察组治疗总有效率95.12%(39/41)远高于对照组78.05%(32/41),差异有统计学意义(P<0.05); 两组治疗前膝关节活动度及功能评分差异均无统计学意义(P>0.05); 与对照组相比,观察组治疗后膝关节活动度及功能评分均较高,差异有统计学意义(P<0.05); 与对照组相比,观察组治疗后TNF-α,IL-1及IL-6水平均较低,差异有统计学意义(P<0.05); 治疗过程中,两组均未出现恶心呕吐、皮肤过敏等不良反应。结论:加味益肾强骨汤与三步推拿点穴手法联合治疗膝骨性关节炎,可有效改善患者膝关节活动度及功能,减轻炎症反应症状,治疗效果较为显著,且安全性较高,在临床治疗中具有推广价值。
Abstract:
Abstract Objective:To explore the clinical effect of modified Yishenqianggu soup combined with Three-step massage in the treatment of knee osteoarthritis. Methods:We select 82 patients with knee osteoarthritis in our hospital from August 2015 to February 2017, and they were divided into observation group and control group according to the random number table, 41 cases in each group. The control group was treated with sodium hyaluronate combined with the Three-step massage, while the observation group was treated with modified Yishenqianggu soup combined with Three-step massage. During four courses of treatment time, the therapeutic effect and the occurrence of adverse reactions were observed.(TNF-α), interleukin-6(IL-6)and interleukin-1(IL-1)levels, Knee mobility, functional score and changes of life quality were measured before and after treatment. Results: The total effective rate of observation group 95.12%(39/41)is much higher than that of the control group 78.05%(32/41), and the difference was statistically significant(P<0.05). There was no statistically significant difference between the activity and function scores of the two groups(P<0.05). Compared with the control group, the activity and function score of the knee joint was higher in observation group, and the difference was statistically significant(P<0.05). Compared with the control group, the levels of TNF-α, Il-1 and Il-6 were lower in the observation group after treatment, and the difference was statistically significant(P<0.05). During the treatment, neither group showed any adverse reactions such as nausea, vomiting, and skin irritation. Results:The total effective rate was 95.12%(39/41)in the observation group, which was much higher than that in the control group(78.05%, 32/41), and the difference was statistically significant(P<0.05).There was no significant difference in knee mobility and functional score between the two groups(P>0.05).Compared with the control group, the activity and function scores of the knee in the observation group were higher than those in the control group, the difference was statistically significant(P<0.05).Compared with the control group, the levels of TNF-, IL-1 and IL-6 in the observation group were lower, the difference was statistically significant(P<0.05).Compared with the control group, the quality of life scores of the observation group after treatment were higher, the difference was statistically significant(P<0.05).During the course of treatment, there were no adverse reactions such as nausea and vomiting, skin allergy and so on. Conclusion:Modified Yishenqianggu soup combined with Three-step massage can effectively improve the knee joint activity and function, reduce the inflammatory response and improve the quality of life. The treatment effect is obvious, and the safety is much higher.

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备注/Memo

备注/Memo:
基金项目:陕西省社会发展科技攻关项目(2015SF078)
更新日期/Last Update: 2018-01-15