[1]田雪梅,年芳红,王海东,等.“瘀方”治疗中晚期类风湿关节炎(痰瘀痹阻证)临床疗效观察[J].中国中医骨伤科杂志,2017,25(05):22-25，29.
　TIAN Xuemei NIAN Fanghong WANG Haidong YANG Delong LI Weiqing JIN Fangmei.Clinical Efficacy of “Blood Stasis” Prescription for Treating with Rheumatoid Arthritis of Middle-late Stage[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2017,25(05):22-25，29.
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“瘀方”治疗中晚期类风湿关节炎(痰瘀痹阻证)临床疗效观察()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第25卷
期数:
2017年05期
页码:
22-25，29
栏目:
临床研究
出版日期:
2017-05-08

文章信息/Info

Title:
Clinical Efficacy of “Blood Stasis” Prescription for Treating with Rheumatoid Arthritis of Middle-late Stage
文章编号:
1005-0205(2017)05-0022-04
作者:
田雪梅1;  年芳红2;  王海东1;  杨德龙2;  李伟青1;  金芳梅1
1.甘肃省中医院(兰州,730050)
2.甘肃中医药大学
Author(s):
TIAN Xuemei1 NIAN Fanghong2 WANG Haidong1 YANG Delong2 LI Weiqing1 JIN Fangmei1
1.Gansu Hospital of Traditional Chinese Medicine,Lanzhou 730050,China;
2.Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China.
关键词:
瘀方;  类风湿关节炎;  临床疗效
Keywords:
“Blood stasis” prescription;  rheumatoid arthritis(RA);  clinical efficacy
分类号:
R684.3
文献标志码:
A
摘要:
目的:观察武威汉代医简“瘀方”治疗中晚期类风湿关节炎(痰瘀痹阻证)的安全性及临床疗效。方法:将2016年1月至2016年6月就诊于甘肃省中医院风湿骨病科门诊及住院部中晚期类风湿关节炎(痰瘀痹阻证)患者100例,采用简单随机分组的方法分为治疗组与对照组,每组各50例。治疗组予基础治疗联用“瘀方”,对照组予基础治疗,每组治疗周期均为3个月,观察两组治疗前后中医证侯疗效及相关理化指标变化,评估其安全性及有效性。结果:两组疗效比较,治疗组总有效率96.0%,优于对照组的总有效率84.0%,差异有统计学意义(P<0.05)。治疗组中医证侯疗效的总有效率92.0%,明显优于对照组的总有效率80.0%,差异有统计学意义(P<0.05)。两组关节压痛数、关节肿胀数、晨僵时间、双手平均握力四项均有明显改善,差异有统计学意义(P<0.05),且治疗组对于上述主要症状、体征的改善优于对照组,差异有统计学意义(P<0.05)。实验室指标ESR,CRP,RF,IgG及双手X线片等治疗组也优于对照组,差异有统计学意义(P<0.05)。结论:“瘀方”治疗中晚期类风湿关节炎(痰瘀痹阻证)安全有效。
Abstract:
Objective:To observe the safety and the clinical efficacy of Wuwei Medical Jane “blood stasis” prescription in Han dynasty in the treatment of rheumatoid arthritis of middle-late stage(phlegm and blood stasis syndrome).Methods:From January 2016 to June 2016,100 cases of outpatients and inpatients with rheumatoid arthritis of middle-late stage(phlegm and blood stasis syndrome)were enrolled from the department of rheumatoid bone disease of Gansu hospital of traditional Chinese medicine.The patients were divided into treatment group and control group by simple randomized grouping method,50 cases in each group.The treatment group were given the basic treatment combined with the “blood stasis”,and the control group were given the basic treatment.The treatment period of each group was 3 months.The curative effect of Chinese medical syndrome and the changes of the related physical and chemical indexes were observed before and after treatment to evaluate the safety and the efficacy.Results:Comparison of the efficacy of the two groups:the total effective rate was 96.0% in the treatment group,better than the total effective rate of 84.0% in the control group(P<0.05).The total effective rate of Chinese medical syndrome was 92.0% in the treatment group,obviously better than that of the control group(80.0%)(P<0.05).The joint tenderness counts,joint swelling counts,morning stiffness time and average hands grip strength of both hands in two groups were improved significantly(P<0.05),while the improvement of the main symptoms and signs above in the treatment group was superior to that of the control group(P<0.05),so were the laboratory indicators ESR,CRP,RF,IgG and hands X-ray and so on(P<0.05).Conclusion:“Blood stasis” prescription are safe and effective drugs for treating rheumatoid arthritis of middle-late stage(phlegm and blood stasis syndrome).

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备注/Memo

备注/Memo:
基金项目:甘肃省中医药管理局科研项目(GZK-2015-28)
更新日期/Last Update: 2017-05-01