[1]廖州伟 陈达 马笃军 肖伟 彭力平△.消瘀散及其拆方治疗急性软组织挫伤的实验研究[J].中国中医骨伤科杂志,2016,24(11):1-5.
　LIAO Zhouwei CHEN Da MA Dujun XIAO Wei PENG Liping.Experimental Research of Xiaoyusan and Its Decomposition for Treating Acute Soft Tissue Injury[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2016,24(11):1-5.
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消瘀散及其拆方治疗急性软组织挫伤的实验研究
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第24卷
期数:
2016年11期
页码:
1-5
栏目:
实验研究
出版日期:
2016-11-01

文章信息/Info

Title:
Experimental Research of Xiaoyusan and Its Decomposition for Treating Acute Soft Tissue Injury
文章编号:
1005-0205(2016)11-0001-05
作者:
廖州伟1 陈达1 马笃军2 肖伟2 彭力平2△
1.广州中医药大学第四临床医学院(广州,510006)
2.深圳市中医院
△.通信作者 E-mail:plp001@sina.com
Author(s):
LIAO Zhouwei1 CHEN Da1 MA Dujun2 XIAO Wei2 PENG Liping2△
1.Guangzhou University of Traditional Chinese Medicine,Guangzhou 510006,China;
2.Shenzhen Hospital of Traditional Chinese Medicine,Shenzhen 518033,Guangdong China.
关键词:
消瘀散;  拆方研究;  急性软组织挫伤
Keywords:
Xiaoyusan;  decomposition;  acute soft tissue injury
分类号:
R-33
文献标志码:
A
摘要:
目的:观察消瘀散及其拆方对急性软组织挫伤的疗效差异,选取治疗急性软组织挫伤最优的中药复方。方法:通过正交t值法主药分析表将消瘀散拆方分为12组(其中拆方组11组为A～E和G～L组,全方组为F组),将72只新西兰大白兔造成急性软组织挫伤模型后,随机分配到12组中,各组用药后第3,5天做大体观察评分、光镜下组织病理评分、血液流变检测和血清IL-1β及IL-6含量测定,评分数据用SPSS 17.0统计软件统计。结果:第3,5天各组间的大体观察评分、光镜下组织病理评分、血液流变检测和血清IL-1β及IL-6含量测定均有不同程度的降低,其中B组、K组及全方F组明显优于其余拆方组(P<0.01),K组、F组优于B组(P<0.05),K组、F组比较差异无统计学意义(P>0.05)。结论:B组、K组及全方组对治疗急性软组织挫伤均有较好的疗效,其中K组及全方F组疗效更佳。
Abstract:
Objective:To observe the therapeutic efficacy of Xiaoyusan ointment and its decomposition for treating acute soft tissue injury,in order to choose the optimization of Chinese herbal compound.Methods:Using orthogonal t value design to decompose Xiaoyusan ointment into 12 groups(including 11 decomposition groups A～E and G～L,and Xiaoyusan ointment group F).All 72 New Zealand rabbits,which were made the model of acute soft tissue injury,were divided into above 12 groups randomly.The general observation scores,histopathology scores under microscope,blood rheology,and levels of serum IL-1β and IL-6 were detected at the third and the fifth day after the treatment.The score data were statistical by SPSS 17.0 statistical software.Results:The general observation scores,the histopathology scores,each index of blood rheology,and levels of IL-1β and IL-6 were decreased in each group at the third and the fifth day.The group B,group K and group F were obviously better than the other decomposition groups(P<0.01).The group K and group F were obviously better than the group B(P<0.05).There was no statistical difference between group K and group F(P>0.05).Conclusion:Group B,group K and group F have great therapeutic effect in treating acute soft tissue injury,and group K and group F are better.

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更新日期/Last Update: 2016-11-15