[1]朱立国 银河 魏戌 冯敏山△ 刘劲松 张淳 李智尧 马佳.宣痹洗剂治疗膝骨关节炎的疗效观察[J].中国中医骨伤科杂志,2016,24(03):9-13.
　ZHU Liguo YIN He WEI Xu FENG Minshan LIU Jingsong ZHANG Chun LI Zhiyao MA Jia.Curative Effect of Xuanbi Lotion on Treating Knee Osteoarthritis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2016,24(03):9-13.
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宣痹洗剂治疗膝骨关节炎的疗效观察
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第24卷
期数:
2016年03期
页码:
9-13
栏目:
临床研究
出版日期:
2016-03-03

文章信息/Info

Title:
Curative Effect of Xuanbi Lotion on Treating Knee Osteoarthritis
文章编号:
1005-0205(2016)03-0009-05
作者:
朱立国1 银河1 魏戌1 冯敏山1△ 刘劲松1 张淳1 李智尧1 马佳1
1.中国中医科学院望京医院(北京,100102)
△.通信作者 E-mail:milkywaymoon@163.com
Author(s):
ZHU Liguo1 YIN He1 WEI Xu1 FENG Minshan1△ LIU Jingsong1 ZHANG Chun1 LI Zhiyao1 MA Jia1
1.Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China.
关键词:
膝骨关节炎;  宣痹洗剂;  热敷熏洗;  临床疗效
Keywords:
knee osteoarthritis;  xuanbi lotion;  heat fumigation;  clinical efficacy
分类号:
R274.39
文献标志码:
A
摘要:
目的:评价宣痹洗剂治疗膝骨关节炎(Knee Osteoarthritis,KOA)的临床疗效。方法:采用随机对照的研究方法,纳入早中期KOA患者(寒湿痹阻,瘀血阻络型)120例,试验组60例,对照组60例。试验组接受宣痹洗剂患膝热敷熏洗,每日2次,每次20 min,疗程为2周。对照组接受双氯芬酸二乙胺乳胶剂患膝擦涂,每日2次,疗程为2周。在治疗的第3,7,14天,及疗程结束后2周应用VAS疼痛积分及HSS膝关节积分、膝关节活动范围评价疗效。结果:治疗结束后2周,试验组总有效率为85%,对照组总有效率为59%(P<0.01)。HSS膝关节评分、VAS疼痛积分、膝关节活动范围评价,均在治疗第14天开始差异有统计学意义(P<0.01),且试验组均优于对照组。试验组有1例患者外敷药物处皮肤周缘出现红疹,停药后症状自行消失,未发现其它不良反应。结论:宣痹洗剂可有效改善早、中期KOA的临床症状,其短期疗效稳定,安全性较高。
Abstract:
Objective: To evaluate the curative effect of Xuanbi lotion on treating knee osteoarthritis. Methods: The randomized controlled methods were used,the 120 patients with early and middle stage of KOA were randomly divided into test group and control group(60 cases in each group). The patients of test group were accepted the hot compress on knee by Xuanbi lotion, 2 times a day, 20 minutes each time, for 2 weeks. The patients of control group were received the Didofenac Diethylamine Gel brushing coated the knee, 2 times a day, for 2 weeks. The functional evaluation were performed by the VAS pain score, the HSS score, and the integral movable degree of knee at the 3rd, 7th, 14th days and 2 weeks after treatment(at 28 th days). Results: The total effective rate of test group and control group were 85% and 59% in the 28th days respectively(P<0.01). The VAS pain score, the HSS score, and the integral movable degree of knee were significantly different between the two groups at 14th days and 28th days(P<0.01). Adverse reaction was not found except one patient in the test group got skin rash, and this symptom resolved spontaneously when the treatment was stopped. Conclusion: Xuanbi lotion can effectively and safely improve the clinical symptoms of early and middle stage of KOA.

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备注/Memo

备注/Memo:
基金项目:北京市中医药科技项目(YNZJ2011-06)
更新日期/Last Update: 2016-03-15