[1]胡志勇 程文会 刘清磊 王文娟 周然然 王金榜 杨燕兵.国医大师李士懋发汗法(寒痉汤)治疗寒凝证型颈椎病的多中心随机对照临床研究[J].中国中医骨伤科杂志,2026,34(05):25-31.[doi:10.20085/j.cnki.issn1005-0205.260504]
　HU Zhiyong,CHENG Wenhui,LIU Qinglei,et al.A Multi-Center Randomized Controlled Clinical Study on the Treatment of Cervical Spondylopathy of Cold-Congealing Pattern with National Master of Traditional Chinese Medicine Li Shimao's Diaphoresis Method(HJD)[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2026,34(05):25-31.[doi:10.20085/j.cnki.issn1005-0205.260504]
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国医大师李士懋发汗法(寒痉汤)治疗寒凝证型颈椎病的多中心随机对照临床研究()

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第34卷
期数:
2026年05期
页码:
25-31
栏目:
临床研究
出版日期:
2026-05-10

文章信息/Info

Title:
A Multi-Center Randomized Controlled Clinical Study on the Treatment of Cervical Spondylopathy of Cold-Congealing Pattern with National Master of Traditional Chinese Medicine Li Shimao's Diaphoresis Method(HJD)
文章编号:
1005-0205(2026)05-0025-07
作者:
胡志勇 程文会 刘清磊 王文娟 周然然 王金榜 杨燕兵
1河北省沧州中西医结合医院,河北省中西医结合骨关节病研究重点实验室(筹)(河北 沧州,061000)
2河北省中医院
3衡水市第二人民医院
Author(s):
HU Zhiyong1; CHENG Wenhui1; LIU Qinglei1; WANG Wenjuan1; ZHOU Ranran1; WANG Jinbang2△; YANG Yanbing3
1Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine in Hebei Province,Hebei Key Laboratory of Integrated Traditional and Western Medicine in Osteoarthrosis Research(Preparing),Cangzhou 061000,Hebei China; 2Hebei Provincial Hospital of Traditional Chinese Medicine,Shijiazhuang 050011,China; 3The Second People's Hospital of Hengshui,Hengshui 053000,Hebei China.
关键词:
发汗法;  寒痉汤;  颈椎病;  寒凝证;  颈椎前凸角;  血液流变学;  随机对照试验
Keywords:
diaphoretic method;  Hanjing decoction;  cervical spondylosis;  cold-congealing pattern;  cervical lordosis angle;  hemorheology;  randomized controlled trial
分类号:
R681.5
DOI:
10.20085/j.cnki.issn1005-0205.260504
文献标志码:
A
摘要:
目的:观察国医大师李士懋应用发汗法(寒痉汤)治疗寒凝证型颈椎病的临床效果。方法:选取寒凝证型颈椎病患者480例,随机分为对照组(4个)和观察组,每组96例,4个对照组分别给予颈椎牵引、颈复康颗粒、颈椎针灸、颈椎推拿治疗,观察组给予寒痉汤治疗。观察五组患者治疗后的视觉模拟量表(VAS)评分、田中靖久颈椎病症状量表(20分法)评分、颈椎前凸角(CLA)、血浆黏度(PV)、红细胞压积(HCT)及临床疗效。结果:与4个对照组治疗前比较,五组患者治疗后VAS评分、颈椎病症状、颈椎前凸角、血浆黏度、红细胞压积等明显改善,差异均有统计学意义(P<0.05)。观察组总有效率为94.79%,4个对照组总有效率分别为82.29%,79.17%,84.38%和85.42%,观察组总有效率明显高于4个对照组,与4个对照组比较总有效率差异有统计学意义(P<0.05)。观察组颈椎前凸角改善幅度不及牵引组、推拿组,差异有统计学意义(P<0.05),但在疼痛缓解、血液流变学指标改善方面优势显著,差异有统计学意义(P<0.05)。观察组不良反应发生率为6.25%(6/96),对照组总不良反应发生率为7.50%(29/384),组间差异无统计学意义(P>0.05),所有不良反应经对症处理后均缓解,未出现严重不良事件。结论:发汗法能够有效治疗寒凝证型颈椎病,缓解临床症状,减轻疼痛,改善颈椎前凸角及血液流变学指标,而且安全性高,值得临床推广应用。
Abstract:
Objective:To observe the clinical efficacy of the diaphoretic method developed by Li Shimao in treating cervical spondylosis with the cold-congealing pattern.Methods:A total of 480 patients with cervical spondylosis of cold-congealing pattern were randomly assigned to four control groups and one observation group,with 96 cases in each group.The four control groups received cervical traction,Jingfukang granules,cervical acupuncture,and cervical tuina manipulation,respectively.The observation group was treated with Hanjing decoction(HJD)administered according to the diaphoretic method.Visual analogue scale(VAS)scores,Tanaka cervical spondylotic radiculopathy symptom score(20-point),cervical lordosis angle(CLA),plasma viscosity(PV),hematocrit(HCT),and clinical efficacy were evaluated before and after treatment in all five groups.Results:Compared with baseline,all five groups showed significant improvement after treatment in VAS scores,cervical spondylosis symptom scores,CLA,PV,and HCT(all P<0.05).The overall response rate was 94.79% in the observation group,and 82.29%,79.17%,84.38%,and 85.42% in the four control groups,respectively.The overall response rate in the observation group was significantly higher than that in each control group(P<0.05).The observation group showed a smaller improvement in CLA than the traction and tuina manipulation groups(P<0.05),but demonstrated significant advantages in pain relief and hemorheological improvement.The incidence of adverse reactions in the observation group was 6.25%(6/96),while the total incidence of adverse reactions in the control groups was 7.50%(29/384).The difference between the groups was not statistically significant(P>0.05).All adverse reactions resolved spontaneously or were alleviated with symptomatic treatment,and no serious adverse events occurred.Conclusion:The diaphoretic method is effective for the treatment of cervical spondylosis of cold-congealing pattern.It alleviates clinical symptoms,reduces pain,improves cervical lordosis angle and hemorheological indices,and demonstrates good safety,suggesting that it warrants broader clinical application.

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(收稿日期:2025-10-21)

备注/Memo

备注/Memo:
基金项目:“十二五”国家科技支撑计划项目(2013BAI13B02)
河北省中医药管理局项目(2022258)
△通信作者 E-mail:wjbshjzh138@sina.com
更新日期/Last Update: 2026-05-15