[1]李月轩,王晓东,陈玮玮,等.靶点射频热凝术联合臭氧消融术治疗 椎间盘源性腰痛的临床研究[J].中国中医骨伤科杂志,2025,33(01):65-68+73.[doi:10.20085/j.cnki.issn1005-0205.250114]
　LI Yuexuan,WANG Xiaodong,CHEN Weiwei,et al.Clinical Study of Target Radiofrequency Thermocoagulation Combined with Ozone Ablation for the Treatment of Discogenic Lower Back Pain[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2025,33(01):65-68+73.[doi:10.20085/j.cnki.issn1005-0205.250114]
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靶点射频热凝术联合臭氧消融术治疗 椎间盘源性腰痛的临床研究()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第33卷
期数:
2025年01期
页码:
65-68+73
栏目:
临床论著
出版日期:
2025-01-15

文章信息/Info

Title:
Clinical Study of Target Radiofrequency Thermocoagulation Combined with Ozone Ablation for the Treatment of Discogenic Lower Back Pain
文章编号:
1005-0205(2025)01-0065-04
作者:
李月轩1; 王晓东1; 陈玮玮1; 田晓阳1; 闫鑫1; 李士学1; 裴世深1
1衡水市第四人民医院(河北 衡水,053000)
Author(s):
LI Yuexuan1; WANG Xiaodong1; CHEN Weiwei1; TIAN Xiaoyang1; YAN Xin1; LI Shixue1; PEI Shishen1
1The No.4 People's Hospital of Hengshui,Hengshui 053000,Hebei China.
关键词:
椎间盘源性腰痛;  靶点射频热凝术;  臭氧消融术
Keywords:
discogenic low back pain;  targeted radiofrequency thermocoagulation;  ozone ablation
分类号:
R681.5
DOI:
10.20085/j.cnki.issn1005-0205.250114
文献标志码:
A
摘要:
目的:探讨靶点射频热凝术与臭氧消融用于椎间盘源性腰痛(DLBP)的效果。方法:选择2022年1月至2023年12月收治的椎间盘源性腰痛患者104例,随机分为观察组和对照组(各52例)。对照组采用靶点射频热凝术治疗,在此基础上观察组加用臭氧消融术。比较两组患者术后总有效率、Oswestry功能障碍指数(ODI)、腰部功能评分、疼痛程度及炎症因子水平。结果:术后观察组总有效率(90.38%)较对照组(75.00%)显著提升,差异有统计学意义(P<0.05); 观察组ODI评分显著低于对照组,下腰疼痛日本骨科协会(JOA)评分显著高于对照组,差异有统计学意义(P<0.05); 两组患者疼痛视觉模拟量表(VAS)评分均逐渐下降,且观察组下降速度更快,术后1个月和3个月VAS评分显著低于对照组,差异有统计学意义(P<0.05); 两组患者炎症因子水平均逐渐降低,且观察组术后1周和术后1个月白细胞介素-6(IL-6)、白细胞介素-8(IL-8)水平显著低于对照组,差异有统计学意义(P<0.05)。结论:对椎间盘源性腰痛患者采用靶点射频热凝术+臭氧消融治疗,可明显缓解患者疼痛情况,抑制炎症发生,临床应用价值较高。
Abstract:
Objective:Exploring the effects of targeted radiofrequency thermocoagulation and ozone ablation on discogenic lower back pain(DLBP).Methods:A total of 104 patients with DLBP from January 2022 to December 2023 were randomly separated into observation group of 52 cases and control group of 52 cases.The control group was treated with targeted radiofrequency thermocoagulation,and the observation group was treated with ozone ablation.The total effective rate,Oswestry disability index(ODI),lumbar function score,pain degree and levels of inflammatory factors were compared between the two groups.Results:After surgery,the total effective rate of the observation group(90.38%)was obviously improved compared to the control group(75.00%)(P<0.05); the ODI score of the observation group was obviously lower than that of the control group,while the Japanese orthopaedic association(JOA)score was obviously higher than that of the control group(P<0.05); the visual analogue scale(VAS)scores of both groups gradually decreased,and the observation group showed a faster decline,the VAS scores at 1 and 3 months after surgery were obviously lower than those of the control group(P<0.05); the levels of inflammatory factors in both groups gradually decreased,and the levels of interleukin-6(IL-6)and interleukin-8(IL-8)in the observation group were obviously lower than those in the control group 1 week and 1 month after surgery(P<0.05).Conclusion:Targeted radiofrequency thermocoagulation plus ozone ablation for DLBP patients can effectively relieve pain and inhibit inflammation,and has high clinical application value.

参考文献/References:

[1] 王静,张晓丹,张森,等.硬膜外腔前侧间隙置管连续阻滞联合腰椎低温等离子消融术治疗椎间盘源性腰痛的效果观察[J].实用临床医药杂志,2020,24(5):36-39.
[2] 周雄元,刘芳.椎间盘源性腰痛患者应用经皮射频热凝消融术结合腰痹通胶囊的临床效果[J].首都食品与医药,2022,29(10):123-125.
[3] ZHAO L,MANCHIKANTI L,KAYE A D,et al.Treatment of discogenic low back pain:current treatment strategies and future options-a literature review[J].Curr Pain Headache Rep,2019,23(11):86.
[4] 李翔,任昊芹,孙亮,等.腰痹通胶囊联合塞来昔布胶囊治疗椎间盘源性腰痛的疗效及对血清炎性因子和疼痛介质的影响[J].现代生物医学进展,2023,23(13):2450-2453.
[5] 王楠,窦智,倪家骧.低温等离子汽化消融术和射频热凝术治疗蝶腭神经痛的病例对照研究[J].中国医药,2021,16(8):1185-1189.
[6] 刘杰,王玉贵.CT引导下经皮穿刺椎间盘臭氧消融术联合中药熏洗与牵引治疗椎间盘突出的临床疗效分析[J].检验医学与临床,2023,20(17):2602-2606.
[7] 胥少汀,葛宝丰,徐印坎.实用骨科学[M].4版.北京:人民军医出版社,2005:2086-2095.
[8] 蒋协远,王大伟.骨科临床疗效评价标准[M].北京:人民卫生出版社,2005:168.
[9] ZHAO W,YANG L,DENG A,et al.Long-term outcomes and predictors of percutaneous radiofrequency thermocoagulation of Gasserian ganglion for maxillary trigeminal neuralgia:a retrospective analysis of 1 070 patients with minimum 2-year follow-up[J].Ann Med,2022,54(1):2420-2430.
[10] WANG Z,SU X,YU Y,et al.A review of literature and meta-analysis of one-puncture success rate in radiofrequency thermocoagulation with different guidance techniques for trigeminal neuralgia[J].Eur J Med Res,2022,27(1):141.
[11] 张青.臭氧消融术联合射频热凝靶点术治疗腰椎间盘突出症患者的效果[J].中国民康医学,2021,33(14):35-37.
[12] 黄锦益,韦克,邓军,等.靶点射频热凝术联合臭氧消融术治疗腰椎间盘突出症的临床疗效[J].中国临床医生杂志,2021,49(3):281-284.
[13] 杨庆法,于红光,王勇,等.CT引导下射频热凝联合臭氧消融术治疗腰椎间盘源性髋关节疼痛的临床研究[J].现代医用影像学,2018,27(3):770-771.
[14] 崔涛,李健,王健秀.经皮射频靶点热凝联合臭氧消融对腰椎间盘突出症患者炎性因子及临床疗效的影响[J].颈腰痛杂志,2018,39(3):316-319.
[15] DJURIC N,YANG X,OSTELO R W J G,et al.Disc inflammation and Modic changes show an interaction effect on recovery after surgery for lumbar disc herniation[J].Eur Spine J,2019,28(11):2579-2587.
[16] 陈林,李波,冉胜强,等.骨科微创技术对腰椎间盘突出症的疗效及血清炎性因子水平的影响[J].贵州医科大学学报,2019,44(3):369-372.
[17] JOHNSON Z I,SCHOEPFLIN Z R,CHOI H,et al.Disc in flames:roles of TNF-α and IL-1β in intervertebral disc degeneration[J].Eur Cell Mater,2015,30:104-116.
[18] 林磊,李般若,王青平,等.腰椎间盘突出物中IL-8、IL-10表达与神经根性疼痛相关性分析[J].临床军医杂志,2017,45(5):514-516.

备注/Memo

备注/Memo:
基金项目:衡水市2023年度科技计划项目(2023014047Z)
更新日期/Last Update: 2025-01-15