[1]周志航 郑广程 刘元梅.富血小板血浆联合康复训练治疗肱骨外上髁炎[J].中国中医骨伤科杂志,2021,29(02):37-40.
 ZHOU Zhihang ZHENG Guangcheng LIU Yuanmei.Efficacy of Platelet-Rich Plasma Combined with RehabilitationTraining on Lateral Epicondylitis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2021,29(02):37-40.
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富血小板血浆联合康复训练治疗肱骨外上髁炎()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第29卷
期数:
2021年02期
页码:
37-40
栏目:
临床论著
出版日期:
2021-02-15

文章信息/Info

Title:
Efficacy of Platelet-Rich Plasma Combined with RehabilitationTraining on Lateral Epicondylitis
文章编号:
1005-0205(2021)02-0037-04
作者:
周志航1 郑广程1 刘元梅1
1山东青州市中医院(山东 青州,262500)
Author(s):
ZHOU Zhihang1 ZHENG Guangcheng1 LIU Yuanmei1
1Qingzhou Hospital of Traditional Chinese Medicine,Qingzhou 262500,Shandong China.
关键词:
富血小板血浆 康复训练 糖皮质激素 肱骨外上髁炎 疗效
Keywords:
platelet-rich plasma(PRP) rehabilitation training glucocorticoid lateral epicondylitis curative effect
分类号:
R686
文献标志码:
A
摘要:
目的:探讨自体富血小板血浆(PRP)局部注射联合康复训练治疗肱骨外上髁炎的临床疗效。方法:选取2016年1月至2019年1月收治的肱骨外上髁炎患者48例,随机分为治疗组和对照组(各24例),治疗组采用PRP局部注射,对照组采用糖皮质激素(使用同等剂量的醋酸泼尼松龙注射液和利多卡因)局部注射,两组患者均在术后进行康复训练治疗,分别在治疗前、治疗后1个月、3个月及12个月,对两组患者进行疼痛视觉模拟量表(VAS)评分、Mayo肘关节功能(MEPS)评分及上肢功能障碍(DASH)评分,同时观察不良反应及并发症。结果:两组VAS,MEPS和DASH评分比较,治疗前差异无统计学意义(P>0.05); 治疗后1个月两组评分均较治疗前明显改善,对照组优于治疗组,差异有统计学意义(P<0.05); 治疗后3个月两组评分均较治疗前明显改善,但组间比较差异无统计学意义(P>0.05); 治疗后12个月两组评分均较治疗前明显改善,治疗组优于对照组,差异有统计学意义(P<0.05)。结论:自体富血小板血浆局部注射联合康复训练治疗肱骨外上髁炎,能减轻患者疼痛,改善患肘关节功能,安全性较高,较糖皮质激素组远期效果更好,值得临床推广应用。
Abstract:
To investigate the effect of platelet-rich plasma(PRP)combined with rehabilitation training on lateral epicondylitis.Methods:48 patients with the lateral epicondylitis were divided into treatment group(n=24)and control group(n=24)by random number table method from January 2016 to January 2019.The treatment group was given PRP,and the control group was given glucocorticoid(prednisolone acetate and lidocaine).All the patients were given the same rehabilitation training after treatment.The visual analogue scale(VAS),Mayo elbow performance score(MEPS),and disabilities of the arm shoulder and hand(DASH)score were compared between the two groups before treatment and 1st,3rd,12th month after treatment,and adverse reactions and complications were observed at the same time.Results:There was no significantly different between VAS,MEPS and DASH before treatment(P>0.05).After 1 month,the patient in the two groups were better than before treatment,but patients in the control group were better than those in the treatment group(P<0.05).After 3 months treatment,there was no significantly different between VAS,MEPS and DASH,but the patients in the two groups were better than before treatment(P>0.05).After 12 months,the patients in the two groups were better than before treatment,but the patients in the treatment group were better than those in the control group(P<0.05).Conclusion:PRP combined with rehabilitation training can relieve pain,imoprove the function of elbow joint,have good safety,the long-term effect of the PRP is better than that of the glucocorticoid,it is worth promoting in the clinic.

参考文献/References:

[1] CANALEST.坎贝尔骨科学[M].王岩,译.12版.北京:人民军医出版社,2013:2085-2088.
[2] LANDESBERG R,ROY M,GLICKMAN R S.Quantification of growth factor levels using a simplified method of platelet-rich plasma gel pre paration[J].J Oral Maxillofac Surg,2000,58(3):297-300.
[3] 谭冠先.疼痛诊疗学[M].北京:人民卫生出版社,2014:36-37.
[4] CUSICK M C,BONNAIG N S,AZAR F M,et al.Accuracy and reliability of the mayo elbow performance score[J].J Hand Surg Am,2014,39(6):1146-1150.
[5] DIXON D,JOHNSTON M,QUEEN M,et al.The disabilities of the arm,shoulder and hand questionnaire(DASH)can measure the impairment,activity limitations and participation restriction constructs from the international classification of functionning,disability and health(ICF)[J].BMC Musculoskelet Disord,2008,9:114.
[6] ALIZADEHKHAIYAT O,FROSTICK S P.Electromyographic assessment of forearm muscle function in tennis players with and without lateral epicondylitis[J].J Electromyogr Kinesiol,2015,25(6):876-886.
[7] CALANDRUCCIO J H,STEINER M M.Autologous blood and platelet-rich plasma injections for treatment of lateral epicondylitis[J].Orthop Clin North Am,2017,48(3):351.
[8] MARQUES L F,STESSUK T,CAMARGO I C,et al.Platelet-rich plasma:methodological aspects and clinical applications[J].Platelets,2015,26(2):101-113.
[9] 王皓楠,王继宏,温树正.富血小板血浆:在肌腱和韧带损伤修复中的应用[J].中国组织工程研究,2019,23(30):4875-4881.
[10] BOSWELL S G,COLE B J,SUNDMAN E A,et al.Platelet-rich plasma:a milieu of bioactive factors[J].Arthroscopy,2012,28(3):429-439.
[11] FOSTER T E,PUSKAS B L,MANDELBAUM B R,et al.Platelet-rich plasma:from basic science to clinical applications[J].Am J Spots Med,2009,37(11):2259-2272.
[12] 李方奇,杨睿,侯景义,等.富血小板血浆治疗腱病概况[J].中华关节外科杂志(电子版),2019,13(3):335-341.
[13] STASINOPOULOS D,STASINOPOULOS I,PANTELIS M,et al.Comparison of effects of a home exercise programme and a supervised exercise for the management of lateral elbow tendinopathy[J].Br J Sports Med,2010,44(8):579-583.
[14] 杨雨洁,朱毅.离心肌力训练在软组织损伤康复中的研究进展[J].中国康复医学杂志,2015,30(6):615-619.
[15] ?HBERG L,ALFREDSON H.Effects on neovascularisation behind the good results with eccentric training in chronic midportion Achilles tendinosis[J].Knee Surgery,Sports Traumatology,Arthroscopy,2004,12(5):465-470.

更新日期/Last Update: 2021-02-15