[1]程后庆,张永,刘刚,等.抗生素骨水泥表面置入在四肢感染创面治疗中的应用[J].中国中医骨伤科杂志,2023,31(09):50-53+57.[doi:10.20085/j.cnki.issn1005-0205.230909 ]
　CHENG Houqing,ZHANG Yong,LIU Gang,et al.Application of Antibiotic Bone Cement Surface Placement in Infected Wounds of Extremities[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2023,31(09):50-53+57.[doi:10.20085/j.cnki.issn1005-0205.230909 ]
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抗生素骨水泥表面置入在四肢感染创面治疗中的应用 ()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第31卷
期数:
2023年09期
页码:
50-53+57
栏目:
临床报道
出版日期:
2023-09-15

文章信息/Info

Title:
Application of Antibiotic Bone Cement Surface Placement in Infected Wounds of Extremities
文章编号:
1005-0205(2023)09-0050-04
作者:
程后庆1; 张永1; 刘刚1; 陈时雨1; 胡韬1; 黄宇1
1芜湖市中医医院骨科(安徽 芜湖,241000)
Author(s):
CHENG Houqing1; ZHANG Yong1; LIU Gang1; CHEN Shiyu1; HU Tao1; HUANG Yu1
1Department of Orthopedics,Wuhu Hospital of Traditional Chinese Medicine,Wuhu 241000,Anhui China.
关键词:
抗生素;  骨水泥置入;  清创;  感染创面
Keywords:
antibiotic;  bone cement surface implantation;  debridement;  infected wound
分类号:
R681.2
DOI:
10.20085/j.cnki.issn1005-0205.230909
文献标志码:
B
摘要:
目的:探索治疗四肢感染性创面的简单方法。方法:收集2021年1月至2022年11月共26例四肢感染病例,创面清创后采用抗生素骨水泥表面置入,待降钙素原(PCT)、C-反应蛋白(CRP)、红细胞沉降率(ESR)炎症指标转阴后根据创面软组织条件,分别给予植皮或者皮瓣移植覆盖创面。结果:26例感染创面经抗生素水泥覆盖后平均(2.00±0.50)d降钙素原转阴,平均(4.00±1.75)d C-反应蛋白转阴,平均(8.50±2.50)d红细胞沉降率转阴,16例采用游离植皮覆盖创面,6例局部转移或近距离带蒂皮瓣移植覆盖创面,4例创面较小换药后痊愈。随访6个月未见伤口再次溃破。结论:抗生素骨水泥表面置入能有效控制伤口的感染,诱导创面软组织再生,为下一步创面覆盖提供较好的基床,无须游离皮瓣或远距离带蒂皮瓣移植覆盖创面,操作简便,便于推广应用。
Abstract:
Objective:To explore the simple therapeutic method in treating infectious wound of limbs.Methods:A total of 26 cases of limbs infection from January 2021 to November 2022 were collected.After wound debridement,antibiotic bone cement was implanted on the surface.When the inflammatory indexes of procalcitonin(PCT),C reactive protein(CRP),erythrocyte sedimentation rate(ESR)became negative,skin grafting or flap transplantation was given to cover the wound according to the conditions of the soft tissue.Results:26 infected wounds were covered with antibiotic cement,and PCT became negative in(2.00±0.50)d,CRP became negative in(4.00±1.75)d,ESR became negative in(8.50±2.50)d.16 cases were covered with free skin grafting,and 6 cases were covered with local metastasis or proximal pedicled flap transplantation,and 4 cases were cured after minor wound dressing change.No wound burst again in 6 months of follow-up.Conclusion:Surface implantation of antibiotic bone cement can effectively control wound infection,induce wound soft tissue regeneration,and provide a better base for the next step of wound coverage,without free flap or remote pedicled flap transplantation to cover the wound,easy to operate and easy to popularize.

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备注/Memo

备注/Memo:
基金项目:2019 年度安徽高校自然科学研究项目( KJ2019A1088)
2022年安徽中医药大学临床科研项目(2021LCWH02)
更新日期/Last Update: 2023-09-01