[1]徐晓艳,郑佳乐,竺闻雷,等.肺癌脊柱转移患者中医证素及证型分布特征研究[J].中国中医骨伤科杂志,2023,31(05):18-23.[doi:10.20085/j.cnki.issn1005-0205.230504]
 XU Xiaoyan,ZHENG Jiale,ZHU Wenlei,et al.Distribution Characteristics Study on TCM Syndrome Elements and Syndrome Types of Spinal Metastasis of Lung Cancer[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2023,31(05):18-23.[doi:10.20085/j.cnki.issn1005-0205.230504]
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肺癌脊柱转移患者中医证素及证型分布特征研究()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第31卷
期数:
2023年05期
页码:
18-23
栏目:
临床研究
出版日期:
2023-05-15

文章信息/Info

Title:
Distribution Characteristics Study on TCM Syndrome Elements and Syndrome Types of Spinal Metastasis of Lung Cancer
文章编号:
1005-0205(2023)05-0018-06
作者:
徐晓艳12郑佳乐13竺闻雷4马俊明1尹萌辰1△
1上海中医药大学附属龙华医院(上海,200032)
2上海市普陀区人民医院
3山西省晋城大医院
4上海交通大学附属第六人民医院
Author(s):
XU Xiaoyan12ZHENG Jiale13ZHU Wenlei4MA Junming1YIN Mengchen1△
1Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China;
2Putuo District People's Hospital of Shanghai,Shanghai 200060,China;
3Jincheng University Hospital of Shanxi Province,Jincheng 048006,Shanxi China;
4The Sixth People's Hospital Affiliated to Shanghai Jiao Tong University,Shanghai 200233,China.
关键词:
肺癌脊柱转移 肺癌骨转移 证素 聚类分析 证素辨证学
Keywords:
spinal metastasis in lung cancer bone metastasis in lung cancer syndrome elements cluster analysis syndrome differentiation
分类号:
R274.39
DOI:
10.20085/j.cnki.issn1005-0205.230504
文献标志码:
A
摘要:
目的:探讨肺癌脊柱转移中医证素、证型分布特征,以期为肺癌脊柱转移的中医临床辨证论治提供参考。方法:选择2020年1月至2022年2月就诊,符合入组标准的患者105例,收集患者病历资料及四诊信息,参考《证素辨证学》中的简化计量方法,对患者的证素进行统计分析,并聚类出证型分布特征。结果:肺癌脊柱转移病位证素以肺、脾、肾多见,病性证素以气虚、阳虚、湿邪多见。病位证素筋骨在不同病理类型的分布中差异有统计学意义(P<0.05),其余各证素基于性别、年龄段、病理类型、化疗时间的分布差异均无统计学意义(P>0.05)。证素经聚类分析得出常见中医证型为阳气亏虚证、痰湿内阻证、脾肾亏虚证、阴虚血瘀证、肝郁气滞证。结论:肺癌脊柱转移常见病位证素为肺、脾、肾,常见病性证素为气虚、阳虚、湿,常见中医证型为阳气亏虚证、痰湿内阻证、脾肾亏虚证、阴虚血瘀证、肝郁气滞证,为肺癌脊柱转移患者的临床辨证论治提供了理论基础。
Abstract:
Objective:To explore the distribution characteristics about traditional Chinese medicine(TCM)syndrome elements and syndrome types of spinal metastasis of lung cancer,then provide guidance for clinical diagnosis and treatment.Methods:105 patients during January 2020 to February 2022 who met the inclusion criteria were selected.The medical information and the basic symptoms in terms of TCM of patients were collected by using the TCM clinical case questionnaire of spinal metastasis of lung cancer designed by this research,and the syndrome elements of patients were statistically analyzed with reference to the simplified measurement method in syndrome differentiation,and cluster the distribution characteristics of syndrome types.Results:Lung,spleen and kidney were the most common location elements in patients of spinal metastasis of lung cancer.Qi deficiency,Yang deficiency and dampness-evil were the most common symptom elements.There were significant differences in the distribution of tendon and bone about different pathologic types,and there were no significant differences in the distribution of other syndrome elements based on different gender,age,pathological type and chemotherapy treating time.Cluster analysis of syndrome elements showed that the common TCM syndrome types were Yang deficiency syndrome,phlegm and dampness stagnation syndrome,spleen and kidney deficiency syndrome,Yin deficiency and blood stasis syndrome,liver depression and Qi stagnation syndrome.Conclusion:Lung,spleen and kidney are the most common location elements in patients of spinal metastasis of lung cancer.Qi deficiency,Yang deficiency and dampness-evil are the most common symptom elements.The common TCM syndrome types are Yang deficiency syndrome,phlegm and dampness stagnation syndrome,spleen and kidney deficiency syndrome,Yin deficiency and blood stasis syndrome,liver depression and Qi stagnation syndrome.It provides a theoretical basis for the clinical dialectical treatment of lung cancer patients with spinal metastasis.

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备注/Memo

备注/Memo:
基金项目:上海市卫计委临床行业专项(20224Y0165)
国家自然科学基金项目(82205145)
通信作者 E-mail:yinmengcheng0513@126.com
更新日期/Last Update: 2023-05-10