[1]张乐,杨嘉△,黄承军.针刀压敏点联合芍药甘草汤治疗气血两虚兼血瘀型神经根型颈椎病的疗效[J].中国中医骨伤科杂志,2022,30(09):31-35+42.
　ZHANG Le,YANG Jia,HUANG Chengjun.Efficacy Analysis of Acupuncture Pressure-Sensitive Points Combined with Shaoyao Gancao Decoction on the Treatment of Cervical Spondylotic Radiculopathy of Qi and Blood Deficiency and Blood Stasis Type[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2022,30(09):31-35+42.
点击复制

针刀压敏点联合芍药甘草汤治疗气血两虚兼血瘀型神经根型颈椎病的疗效()
分享到：

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第30卷
期数:
2022年09期
页码:
31-35+42
栏目:
临床研究
出版日期:
2022-09-15

文章信息/Info

Title:
Efficacy Analysis of Acupuncture Pressure-Sensitive Points Combined with Shaoyao Gancao Decoction on the Treatment of Cervical Spondylotic Radiculopathy of Qi and Blood Deficiency and Blood Stasis Type
文章编号:
1005-0205(2022)09-0031-05
作者:
张乐1; 杨嘉1△; 黄承军1
1广西中医药大学第三附属医院(柳州市中医医院)(广西 柳州,545001)
Author(s):
ZHANG Le1; YANG Jia1△; HUANG Chengjun1
1The Third Affiliated Hospital of Guangxi University of Chinese Medicine(Liuzhou Hospital of Traditional Chinese Medicine),Liuzhou 545001,Guangxi China.
关键词:
神经根型颈椎病;  芍药甘草汤;  针刀;  压敏点
Keywords:
cervical spondylotic radiculopathy;  Shaoyao liquorice decoction;  needle knife;  pressure sensitive point
分类号:
R255.3; R255.6
文献标志码:
A
摘要:
目的:探讨针刀压敏点联合芍药甘草汤治疗气血两虚兼血瘀型神经根型颈椎病(CSR)的疗效。方法:选择2019年10月至2021年7月本院收治的130例气血两虚兼血瘀型神经根型颈椎病患者,随机分为两组,对照组采用芍药甘草汤治疗,观察组采用针刀压敏点联合芍药甘草汤治疗。比较两组颈肩痛疼痛程度、颈椎症状和功能障碍程度、睡眠和生活质量、炎症因子以及不良反应。结果:最终120例完成治疗,进入结果分析,每组各60例。两组患者疼痛视觉模拟量表(VAS)评分、Northwick Park颈痛问卷(NPQ)评分、颈椎功能障碍指数(NDI)评分、匹茨堡睡眠质量指数量表(PSQI)评分、血清白细胞介素(IL)-6、IL-1β、肿瘤坏死因子-α(TNF-α)水平较治疗前降低,差异有统计学意义(P<0.05); 颈椎病临床评价量表(CASCS)评分及健康状况调查简表(SF-36)评分较治疗前增高,差异有统计学意义(P<0.05)。观察组治疗后VAS评分、NPQ评分、NDI评分、PSQI评分、血清IL-6、IL-1β、TNF-α水平低于对照组,差异有统计学意义(P<0.05); CASCS评分、SF-36评分高于对照组,差异有统计学意义(P<0.05)。结论:与芍药甘草汤治疗比较,针刀压敏点联合芍药甘草汤可显著改善神经根型颈椎病疼痛程度和临床症状,降低颈椎障碍程度,提高睡眠和生活质量,可能与针刀压敏点联合芍药甘草汤显著的抗炎效果有关。
Abstract:
Objective:To explore the efficacy of acupuncture pressure-sensitive points combined with Shaoyao gancao decoction on the treatment of cervical spondylotic radiculopathy(CSR)of Qi and blood deficiency and blood stasis type.Methods:A total of 130 CSR patients with Qi and blood deficiency and blood stasis type from October 2019 to July 2021 were selected and randomly divided into two groups.The control group were treated with Shaoyao liquorice decoction,and the observation group were treated with acupotomy pressure sensitive point combined with Shaoyao liquorice decoction.The degree of neck and shoulder pain,cervical symptoms and dysfunction,sleep and quality of life,inflammatory factors and adverse reactions were compared between the two groups.Results:120 cases were treated and entered the results analysis,with 60 cases in each group.The visual analog scale(VAS)and northwick park neck pain questionnaire(NPQ)scores,cervical spine dysfunction index(NDI)scores,Pittsburgh sleep quality index(PSQI)scores,serum interleukin(IL-6),IL-1β,tumor necrosis factor -α(TNF-α)levels in both groups decreased than those before treatment(P<0.05); CASCS scores and SF-36 scores increased than those before treatment(P<0.05).After treatment,VAS scores,NPQ scores,NDI scores,PSQI scores,serum IL-6,IL-1β and TNF-α levels in observation group were lower than those in control group(P<0.05); CASCS scores and SF-36 scores were higher than those in control group(P<0.05).Conclusion:Compared with Shaoyao liquorice decoction,acupotomy pressure sensitive point combined with Shaoyao liquorice decoction can significantly improve the degree of CSR pain and clinical symptoms,reduce the degree of cervical spine disorder,improve sleep and life quality,which may be related to the significant anti-inflammatory effect of acupotomy pressure sensitive point combined with Shaoyao liquorice decoction.

参考文献/References:

[1] 张学思,高景华,王宝剑,等.引火汤治疗椎动脉型颈椎病56例[J].中国中医骨伤科杂志,2020,28(4):41-43.
[2] 中华外科杂志编辑部.颈椎病的分型、诊断及非手术治疗专家共识(2018)[J].中华外科杂志,2018,56(6):401-402.
[3] 国家中医药管理局.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:74-79.
[4] SCOTT J,HUSKISSON E C.Graphic representation of pain[J].Pain,1976,2(2):175-184.
[5] LEAK A M,COOPER J,DYER S,et al.The Northwick Park neck pain questionnaire,devised to measure neck pain and disability[J].Br J Rheumatol,1994,33(5):469-474.
[6] 张鸣生,许伟成,林仲民,等.颈椎病临床评价量表的信度与效度研究[J].中华物理医学与康复杂志,2003,25(3):151-154.
[7] 伍少玲,马超,伍时玲,等.颈椎功能障碍指数量表的效度与信度研究[J].中国康复医学杂志,2008,23(7):625-628.
[8] BUYSSE D J,REYNOLDS 3rd C F,MONK T H,et al.The Pittsburgh Sleep Quality Index:a new instrument for psychiatric practice and research[J].Psychiatry Res,1989,28(2):193-213.
[9] 万崇华,方积乾,汤学良,等.SF-36 量表用于肝癌患者生活质量测定的效果评价[J].肿瘤,2005,25(5):492-494.
[10] 谢瑞,于杰,尹逊路,等.神经根型颈椎病的现代中医治疗研究进展[J].海南医学院学报,2019,25(17):1356-1360.
[11] 钟远鸣,何炳坤,吴卓檀,等.芍药甘草汤治疗腰椎间盘突出症早期疼痛作用机制的网络药理学分析[J].中国组织工程研究,2021,25(20):3194-3201.
[12] 杨昭,张岚.芍药甘草汤加减对中晚期结肠癌癌性疼痛患者生活质量及生存率的影响[J].辽宁中医杂志,2020,47(1):99-102.
[13] 宜娟娟,曹玉举,郭永昌.芍药甘草汤联合针刺治疗急性踝关节扭伤疗效观察[J].中国中医急症,2020,29(2):326-328.
[14] 熊哲,谢家璇,朱鲲博,等.芍药苷调控酸敏感离子通道发挥镇痛作用[J].医药导报,2019,38(11):1403-1407.
[15] 陈进城,林荣,张圆芳,等.基于miR-146a调控NF-κB信号通路探讨芍药甘草汤治疗颈型颈椎病兔颈后肌炎症损伤的作用机制[J].康复学报,2020,30(3):206-211.
[16] 杨芳洁,吴大伟,何坚.基于NLRP3炎性小体探讨芍药甘草汤对神经根型颈椎病大鼠的抗炎镇痛机制[J].福建中医药,2021,52(5):53-54.
[17] JIANG L,LIU H,LI H,et al.Ultrasound-guided needle-knife for de Quervain's disease:a protocol for systematic review and meta-analysis[J].Medicine(Baltimore),2021,100(14):e24877.
[18] XIE K,PAN X,HUANG F,et al.Needle knife therapy plus sodium hyaluronate injection for knee osteoarthritis:a protocol for a systematic review and meta-analysis[J].Medicine(Baltimore),2020,99(46):e23242.
[19] 张义,张莉,郭长青,等.针刀干预对大鼠触发点肌组织P物质和缓激肽的影响[J].中华中医药杂志,2020,35(1):97-100.
[20] 黄京华,何保深,黄伟阳,等.小针刀激痛点治疗颈肩肌筋膜疼痛综合征的临床研究[J].内蒙古中医药,2020,39(6):90-92.
[21] 冯涛,张丽萍.针刀松解法对腰椎间盘突出症根性神经痛模型大鼠镇痛与抗炎效果分析[J].广州中医药大学学报,2019,36(8):1213-1218.

备注/Memo

备注/Memo:
基金项目:广西壮族自治区卫生厅中医药科技专项课题(GZKZ-Z1106)
△通信作者 E-mail:yj1985152@163.com
更新日期/Last Update: 2022-09-10