[1]马涉,于栋△.化痹右归颗粒治疗肝肾亏虚型腰椎间盘突出症的临床观察[J].中国中医骨伤科杂志,2024,32(03):65-69.[doi:10.20085/j.cnki.issn1005-0205.240313]
　MA She,YU Dong.Clinical Study of Huabi Yougui Granule on the Treatment of Liver and Kidney Deficiency Type of Lumbar Disc Herniation[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2024,32(03):65-69.[doi:10.20085/j.cnki.issn1005-0205.240313]
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化痹右归颗粒治疗肝肾亏虚型腰椎间盘突出症的临床观察()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第32卷
期数:
2024年03期
页码:
65-69
栏目:
临床研究
出版日期:
2024-03-15

文章信息/Info

Title:
Clinical Study of Huabi Yougui Granule on the Treatment of Liver and Kidney Deficiency Type of Lumbar Disc Herniation
文章编号:
1005-0205(2024)03-0065-05
作者:
马涉1; 2; 于栋1; 2△
1北京中医药大学(北京,100029)
2北京中医药大学第三附属医院
Author(s):
MA She1; 2; YU Dong1; 2△
1Beijing University of Chinese Medicine,Beijing 100029,China; 2Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing 100029,China.
关键词:
腰椎间盘突出症;  化痹右归颗粒;  清宫正骨流派;  阳化气;  肝肾亏虚
Keywords:
lumbar disc herniation;  Huabi Yougui granule;  Qinggong orthopedic school;  Yang Hua Qi;  liver and kidney deficiency
分类号:
R681.5
DOI:
10.20085/j.cnki.issn1005-0205.240313
文献标志码:
A
摘要:
目的:基于“阳化气”理论,观察清宫正骨流派化痹右归颗粒治疗肝肾亏虚型(偏于阳虚型)腰椎间盘突出症的临床疗效,初步评价其有效性及安全性。方法:选取肝肾亏虚型腰椎间盘突出症患者60例,随机分为中药组和对照组,中药组给予化痹右归颗粒治疗,对照组给予艾瑞昔布片治疗,收集治疗前后的相关资料,对视觉模拟量表(VAS)评分、日本骨科协会(JOA)评分、中医症状分级量化表评分、血清炎症因子(肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6))水平及临床疗效进行统计分析。结果:治疗2周及4周后,两组患者VAS评分均降低,JOA评分均升高,中医证候评分均降低。治疗2周后,对照组VAS评分、JOA评分改善效果优于中药组,中药组的中医证候评分改善优于对照组,差异有统计学意义(P<0.05)。治疗4周后,中药组的VAS评分、JOA评分、中医证候评分、血清学炎症因子的改善效果均优于对照组,差异有统计学意义(P<0.05)。治疗周期中,未见药物过敏反应、胃肠道不适症状等不良反应。结论:基于“阳化气”理论,化痹右归颗粒治疗肝肾亏虚型腰椎间盘突出症可明显减轻腰腿部疼痛,改善生活质量,缓解炎症反应。
Abstract:
Objective:To observe the clinical efficacy of Huabi Yougui granule of Qinggong orthopedic school on the treatment of lumbar disc herniation of liver and kidney deficiency type(inclined to Yang deficiency type)based on the theory of “Yang Hua Qi”,and to evaluate its efficacy and safety.Methods:60 patients with lumbar disc herniation of liver and kidney deficiency were randomly divided into the traditional Chinese medicine(TCM)group and the control group.The patients in the TCM group were given Huabi Yougui granules,and the patients in the control group were given imrecoxib tablets.Visual analogue scale(VAS)score,Japanese orthopaedic association(JOA)score,TCM symptom grading quantitative table score,serum inflammatory factors(tumor necrosis factor-α(TNF-α),interleukin-6(IL-6))levels and clinical efficacy were statistically analyzed.Results:After 2 and 4 weeks of treatment,VAS scores were decreased,JOA scores were increased,and TCM syndrome scores were decreased in the two groups.After 2 weeks of treatment,the improvement of VAS score and JOA score in the control group was better than that in the TCM group,and the improvement of TCM syndrome score in the TCM group was better than that in the control group(P<0.05).After 4 weeks of treatment,the improvement of VAS score,JOA score,TCM syndrome score and serum inflammatory factors in the TCM group were better than those in the control group(P<0.05).During the treatment period,no adverse reactions such as allergic reactions and gastrointestinal symptoms were observed.Conclusion:Huabi Yougui granule can significantly reduce waist and leg pain,improve the quality of life,and relieve inflammatory response on the treatment of lumbar disc herniation with liver and kidney deficiency based on the theory of “Yang Hua Qi”.

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备注/Memo

备注/Memo:
基金项目:北京中医药大学第三附属医院2022年度院内培育项目(BZYSY-2022-PYMS-18)
△通信作者 E-mail:yu_dong01@126.com
更新日期/Last Update: 2024-03-15