[1]汪青,黄昊强,陈勇,等.女性骨质疏松性椎体骨折患者肌少症的危险因素分析[J].中国中医骨伤科杂志,2023,31(06):52-55.[doi:10.20085/j.cnki.issn1005-0205.230609]
　WANG Qing,HUANG Haoqiang,CHEN Yong,et al.Analysis of the Prevalence and Risk Factors of Sarcopenia in Female Patients with Osteoporotic Vertebral Fracture[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2023,31(06):52-55.[doi:10.20085/j.cnki.issn1005-0205.230609]
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女性骨质疏松性椎体骨折患者肌少症的危险因素分析()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第31卷
期数:
2023年06期
页码:
52-55
栏目:
临床研究
出版日期:
2023-06-15

文章信息/Info

Title:
Analysis of the Prevalence and Risk Factors of Sarcopenia in Female Patients with Osteoporotic Vertebral Fracture
文章编号:
1005-0205(2023)06-0052-04
作者:
汪青1; 黄昊强1; 陈勇1; 彭志坚1△
1江苏昆山市中医医院(江苏 昆山,215300)
Author(s):
WANG Qing1; HUANG Haoqiang1; CHEN Yong1; PENG Zhijian1△
1Kunshan Traditional Chinese Medicine Hospital,Kunshan 215300,Jiangsu China.
关键词:
骨质疏松性椎体骨折;  肌少症;  25羟维生素D;  体重指数
Keywords:
osteoporotic vertebral fractures;  sarcopenia;  25(OH)D;  body mass index(BMI)
分类号:
R681.5
DOI:
10.20085/j.cnki.issn1005-0205.230609
文献标志码:
A
摘要:
目的:研究女性骨质疏松性椎体骨折患者肌少症的患病率及危险因素。方法:共纳入286名患有骨质疏松性椎体骨折的女性患者,分为肌少症组与非肌少症组,评估临床及实验室因素,测量骨密度(BMD)、体成分及握力。采用多元Logistic回归分析肌少症的危险因素。结果:286例女性骨质疏松性椎体骨折患者肌少症的患病率为27.97%(86/286)。与无肌少症相比,肌少症组的体重指数(BMI)、前白蛋白、白蛋白、血红蛋白、25(OH)D、骨密度(L1～L4、全髋关节及股骨颈)较低(P<0.05)。二元多因素Logistic逻辑回归分析显示,髋关节骨密度(OR=0.007,95%CI=0.000～0.133)、体重指数(OR=0.762,95%CI=0.678～0.872)及25(OH)D(OR=0.933,95%CI=0.891～0.978)是肌少症发生的保护因素。结论:在女性骨质疏松性椎体骨折患者中,肌少症的发生率较高,其中低体重指数、低25(OH)D及低全髋关节骨密度是肌少症的危险因素,增加营养、维持正常的体重、纠正维生素D不足可能有利于减少肌少症的发生。
Abstract:
Objective:To study the prevalence and risk factors of sarcopenia in female patients with osteoporotic vertebral fracture.Methods:A total of 286 female patients with osteoporotic vertebral fracture were divided into sarcopenia group and non-sarcopenia group.Clinical and laboratory factors were evaluated,and bone mineral density(BMD)and body composition were measured.Multiple Logistic regression was used to analyze the risk factors of sarcopenia.Results:The prevalence of sarcopenia in 286 female patients with osteoporotic vertebral fracture was 27.97%(86/286).Body mass index(BMI),prealbumin,albumin,hemoglobin,25(OH)D,bone mineral density(L1 to L4,total hip and femoral neck)in the sarcopenia group were lower compared with the non-sarcopenia(P<0.05).Binary multivariate Logistic regression analysis showed that hip BMD(OR=0.007,95%CI=0.000-0.133),BMI(OR=0.762,95%CI=0.678-0.872)and 25(OH)D(OR=0.933,95%CI=0.891-0.978)were the protective factors for the occurrence of sarcopenia.Conclusion:The incidence of sarcopenia is higher in female patients with osteoporotic vertebral fractures.Low BMI,low 25(OH)D,and low total hip joint BMD are risk factors for sarcopenia.Increasing nutrition,maintaining normal weight,and correcting vitamin D deficiency may help reduce the occurrence of sarcopenia.

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备注/Memo

备注/Memo:
基金项目:江苏省老年健康项目(LK2021044)
△通信作者 E-mail:13912690058@163.com
更新日期/Last Update: 2023-06-10