[1]张莉莹,陈建锋△,李浩,等.独活寄生汤联合富血小板血浆治疗关节镜清理术后肝肾亏虚型膝骨关节炎[J].中国中医骨伤科杂志,2022,30(12):72-75.
　ZHANG Liying,CHEN Jianfeng,LI Hao,et al.Efficacy of Duhuo Jisheng Decoction Combined with PRP in TreatingKnee Osteoarthritis with Liver and Kidney Deficiency after Arthroscopic Debridement[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2022,30(12):72-75.
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独活寄生汤联合富血小板血浆治疗关节镜清理术后肝肾亏虚型膝骨关节炎()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第30卷
期数:
2022年12期
页码:
72-75
栏目:
临床报道
出版日期:
2022-12-15

文章信息/Info

Title:
Efficacy of Duhuo Jisheng Decoction Combined with PRP in TreatingKnee Osteoarthritis with Liver and Kidney Deficiency after Arthroscopic Debridement
文章编号:
1005-0205(2022)12-0072-04
作者:
张莉莹1; 陈建锋1; 2△; 李浩2; 陈大伟2; 杨傲飞2; 葛梦涛1
1湖北中医药大学(武汉,430061) 2湖北省中医院骨伤科
Author(s):
ZHANG Liying1; CHEN Jianfeng1; 2△; LI Hao2; CHEN Dawei2; YANG Aofei2; GE Mengtao1
1Hubei University of Chinese Medicine, Wuhan 430061,China; 2Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430061,China.
关键词:
膝骨关节炎;  独活寄生汤;  肝肾亏虚型;  富血小板血浆;  关节镜术
Keywords:
knee osteoarthritis;  Duhuo Jisheng decoction;  liver and kidney deficiency;  platelet-rich plasma;  arthroscopes
分类号:
R684.3
文献标志码:
B
摘要:
目的:观察独活寄生汤口服联合富血小板血浆(PRP)注射治疗关节镜下清理术后肝肾亏虚型膝骨关节炎(KOA)的临床疗效。方法:回顾性分析自2019年7月至2021年3月治疗的肝肾亏虚型膝骨关节炎患者49例,所有患者均采用常规关节镜下清理术后注射富血小板血浆,术后当天及术后1周共注射2次; 术后第2天开始口服以独活寄生汤为主方的中药,治疗周期为28 d。分别记录患者术前、术后1周、1个月、3个月、1年及末次随访时的疼痛视觉模拟量表(VAS)评分、西安大略和麦克马斯特大学骨关节炎指数(WOMAC),并统计并发症发生的情况。结果:患者术后1周、1个月、3个月、1年及末次随访的VAS评分和WOMAC与术前相比差异均有统计学意义(P<0.05),且末次随访时疗效观察指标VAS评分(2.34±0.64)、WOMAC(24.04±6.30)与术后1周VAS评分(3.02±0.42)、WOMAC(31.61±3.16)相比差异有统计学意义(P<0.05),总有效率达到97.96%。结论:对于肝肾亏虚型膝骨关节炎患者,在关节镜下清理术后配合独活寄生汤口服联合注射富血小板血浆治疗,可提高关节镜手术的远期疗效。
Abstract:
Objective:To observe the clinical efficacy of Duhuo Jisheng decoction combined with platelet-rich plasma(PRP)on the treatment of knee osteoarthritis(KOA)with liver and kidney deficiency after arthroscopic debridement.Methods:49 patients with liver and kidney deficiency KOA from July 2019 to March 2021 were retrospectively analyzed.All patients were injected with PRP twice after routine arthroscopic debridement on the same day and 1 week after operation.On the second day after operation, they were taken with duhuo jisheng decoction, and the treatment period was 28 d.The visual analogue scale(VAS)score and Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)were recorded before operation, after operation 1 week, 1 month, 3 months, 1 year and last follow-up.And the complications were recorded.Results:There were significant differences in VAS score and WOMAC index after operation 1 week, 1 month, 3 months, 1 year and at last follow-up compared with those before operation(P<0.05).There was significant difference in the last follow-up(the VAS score=2.34±0.64,the WOMAC index=24.04±6.30)and the first week after operation(the VAS score=3.02±0.42,the WOMAC index=31.61±3.16)(P<0.05).The total effective rate was 97.96%.Conclusion:For the KOA patients with liver and kidney deficiency, arthroscopic debridement combined with duhuo jisheng decoction combined with PRP can effectively improve the long-term efficacy of arthroscopic surgery.

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备注/Memo

备注/Memo:
基金项目:国家中医药管理局“熊昌源名老中医药专家传承 工作室”建设项目(国中医药人教函〔2022〕75号) △通信作者 E-mail:chenjianfeng@hbhtcm.com
更新日期/Last Update: 2022-12-10