参考文献/References:
[1] GONZALEZ-MARISCAL L,TAPIA R,CHAMORRO D.Crosstalk of tight junction components with signaling pathways[J].Biochim Biophys Acta,2008,1778(3):729-756.
[2] 苑文超,张华,黄桂成,等.大黄对大鼠脊髓损伤后血-脊髓屏障的保护作用[J].广东医学,2017,38(10):1481-1484.
[3] RAHIMI N.Defenders and challengers of endothelial barrier function[J].Front Immunol,2017,8:1847-1857.
[4] 赵海君,钱易,崔毓桂,等.紧密连接的结构与功能[J].国际生殖健康/计划生育杂志,2013,32(5):384-386.
[5] VAN ITALLIE C M,ANDERSON J M.Architecture of tight junctions and principles of molecular composition[J].Semin Cell Dev Biol,2014,36:157-165.
[6] CITI S.The mechanobiology of tight junctions[J].Biophys Rev,2019,11(5):783-793.
[7] GUNZEL D,FROMM M.Claudins and other tight junction proteins[J].Compr Physiol,2012,2(3):1819-1852.
[8] 王希,廖吕钊,江荣林.肠上皮细胞紧密连接蛋白的结构功能及其调节[J].浙江医学,2018,40(8):895-898.
[9] 杨书香,谭效锋.紧密连接蛋白及其在肺癌中的异常表达[J].现代诊断与治疗,2016,27(9):1606-1608.
[10] 王雪岩,刘瑞霞,郭易楠,等.血管内皮通透性的细胞及信号转导调控机制[J].微循环学杂志,2018,28(4):61-66.
[11] MOENS E,VELDHOEN M.Epithelial barrier biology:good fences make good neighbours[J].Immunology,2012,135(1):1-8.
[12] GUL I S,HULPIAU P,SAEYS Y,et al.Evolution and diversity of cadherins and catenins[J].Exp Cell Res,2017,358(1):3-9.
[13] ISHIYAMA N,SARPAL R,WOOD M N,et al.Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions[J].Nat Commun,2018,9(1):5121-5138.
[14] KOMAROVA Y A,KRUSE K,MEHTA D,et al.Protein interactions at endothelial junctions and signaling mechanisms regulating endothelial permeability[J].Circ Res,2017,120(1):179-206.
[15] 杨柳,楚小玉,赵奇.RhoA对小鼠成釉细胞黏附连接的影响[J].北京大学学报(医学版),2018,50(3):521-526.
[16] TONKIN R S,MAO Y,O'CARROLL S J,et al.Gap junction proteins and their role in spinal cord injury[J].Frontiers in Molecular Neuroscience,2015,7:102-111.
[17] YIN X,FENG L,MA D,et al.Roles of astrocytic connexin-43,hemichannels,and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone[J].J Neuroinflammation,2018,15(1):97-121.
[18] 刘晓静,陶羽,夏玉凤,等.缝隙连接及其在细胞屏障中的作用[J].生理科学进展,2020,51(3):239-241.
[19] 曾山,洪葵.桥粒蛋白与离子转运相关通道[J].中国生物化学与分子生物学报,2015,31(10):1033-1037.
[20] 张轶,李龙江.桥粒在肿瘤侵袭和转移中的作用[J].国际口腔医学杂志,2009,36(2):208-210.
[21] DELVA E,TUCKER D K,KOWALCZYK A P.The desmosome[J].Cold Spring Harb Perspect Biol,2009,1(2):a2543-a2560.
[22] 张利平,王爽,徐屹.上皮细胞连接及其与口腔致病菌间的关系[J].国际口腔医学杂志,2012,39(3):368-372.
[23] VAFADARI B,SALAMIAN A,KACZMAREK L.MMP-9 in translation:from molecule to brain physiology,pathology,and therapy[J].J Neurochem,2016,139(Suppl 2):91-114.
[24] ZHOU Y,YE L,ZHENG B,et al.Phenylbutyrate prevents disruption of blood-spinal cord barrier by inhibiting endoplasmic reticulum stress after spinal cord injury[J].Am J Transl Res,2016,8(4):1864-1875.
[25] 吴小波,张轶行.Meth对大鼠SCI后神经细胞凋亡及wnt/β-catenin信号通路的影响[J].卒中与神经疾病,2019,26(3):261-265.
[26] CUI N,HU M,KHALIL R A.Biochemical and biological attributes of matrix metalloproteinases[J].Prog Mol Biol Transl Sci,2017,147:1-73.
[27] PARK C S,LEE J Y,CHOI H Y,et al.Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury[J].Neurobiol Dis,2020,145:105077-105092.
[28] LEE J Y,NA W H,CHOI H Y,et al.Jmjd3 mediates blood-spinal cord barrier disruption after spinal cord injury by regulating MMP-3 and MMP-9 expressions[J].Neurobiol Dis,2016,95:66-81.
[29] LEE J Y,CHOI H Y,BAIK H H,et al.Cordycepin-enriched WIB-801C from Cordyceps militaris improves functional recovery by attenuating blood-spinal cord barrier disruption after spinal cord injury[J].J Ethnopharmacol,2017,203:90-100.
[30] HUANG C,ZHANG W,CHU F,et al.Patchouli alcohol improves the integrity of the blood-spinal cord barrier by inhibiting endoplasmic reticulum stress through the Akt/CHOP/Caspase-3 pathway following spinal cord injury[J].Frontiers in Cell and Developmental Biology,2021,9:693533-683546.
[31] ZHENG B,ZHOU Y,ZHANG H,et al.Dl-3-n-butylphthalide prevents the disruption of blood-spinal cord barrier via inhibiting endoplasmic reticulum stress following spinal cord injury[J].International Journal of Biological Sciences,2017,13(12):1520-1531.
[32] BHASKARAN N,SHUKLA S,KANWAL R,et al.Induction of heme oxygenase-1 by chamomile protects murine macrophages against oxidative stress[J].Life Sci,2012,90(25/26):1027-1033.
[33] YU D S,CAO Y,MEI X F,et al.Curcumin improves the integrity of blood-spinal cord barrier after compressive spinal cord injury in rats[J].J Neurol Sci,2014,346(1/2):51-59.
[34] 邹德峰,杨晓松,卜繁旺,等.蛇床子素激活wnt/β-catenin信号通路抑制急性脊髓损伤大鼠神经细胞凋亡[J].解剖科学进展,2020,26(3):303-306.
[35] ZHOU H,LIU Y,SUN L,et al.Salvianolic acid B activates Wnt/beta-catenin signaling following spinal cord injury[J].Exp Ther Med,2020,19(2):825-832.
[36] XIANG Z,ZHANG S,YAO X,et al.Resveratrol promotes axonal regeneration after spinal cord injury through activating Wnt/beta-catenin signaling pathway[J].Aging(Albany NY),2021,13(20):23603-23619.
[37] LEE J Y,CHOI H Y,NA W H,et al.Ghrelin inhibits BSCB disruption/hemorrhage by attenuating MMP-9 and SUR1/TrpM4 expression and activation after spinal cord injury[J].Biochimica et Biophysica Acta:Molecular Basis of Disease,2014,1842(12):2403-2412.
[38] 杨盛林,蒲兴魏,罗春山,等.汉防己甲素预处理对脊髓缺血再灌注损伤模型兔的神经保护[J].中国组织工程研究,2022,26(8):1223-1227.
[39] 曾欢欢,黄英如,李子健,等.大黄素对大鼠急性脊髓损伤后继发脊髓水肿的影响[J].中国康复理论与实践,2018,24(4):378-384.
[40] DU F,WANG X,SHANG B,et al.Gastrodin ameliorates spinal cord injury via antioxidant and anti-inflammatory effects[J].Acta Biochim Pol,2016,63(3):589-593.
[41] 胡伟,谢兴奇,屠冠军.骨髓间充质干细胞来源外泌体改善脊髓损伤后血脊髓屏障的完整性[J].中国组织工程研究,2022,26(7):992-998.
[42] WANG H,LIU C,MEI X,et al.Berberine attenuated pro-inflammatory factors and protect against neuronal damage via triggering oligodendrocyte autophagy in spinal cord injury[J].Oncotarget,2017,8(58):98312-98321.
[43] ZHANG D,TANG Q,ZHENG G,et al.Metformin ameliorates BSCB disruption by inhibiting neutrophil infiltration and MMP-9 expression but not direct TJ proteins expression regulation[J].J Cell Mol Med,2017,21(12):3322-3336.
[44] 曾日祥,马勇,赖玉灵.急性脊髓损伤患者外周血hs-CRP、TNF-α、IL-6和IL-10的动态表达及临床意义[J].河北医药,2016,38(10):1509-1511.
[45] ZHANG Q,WANG J,GU Z,et al.Effect of lycopene on the blood-spinal cord barrier after spinal cord injury in mice[J].Biosci Trends,2016,10(4):288-293.
[46] FAN Z K,LV G,WANG Y F,et al.The protective effect of salvianolic acid B on blood-spinal cord barrier after compression spinal cord injury in rats[J].J Mol Neurosci,2013,51(3):986-993.
[47] 刘雪华,周毅,杨晶,等.高压氧对急性脊髓损伤大鼠脊髓组织血管内皮生长因子及缝隙连接蛋白表达的影响[J].中华航海医学与高气压医学杂志,2015,22(6):426-430.
[48] ABOU-MRAD Z,ALOMARI S O,BSAT S,et al.Role of connexins in spinal cord injury:an update[J].Clinical Neurology and Neurosurgery,2020,197:106102-106107.
[49] HUANG C,HAN X,LI X,et al.Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury[J].J Neurosci,2012,32(10):3333-3338.
[50] ZHANG F F,MORIOKA N,KITAMURA T,et al.Lycopene ameliorates neuropathic pain by upregulating spinal astrocytic connexin 43 expression[J].Life Sci,2016,155:116-122.
[51] MAO Y,TONKIN R S,NGUYEN T,et al.Systemic administration of connexin43 mimetic peptide improves functional recovery after traumatic spinal cord injury in adult rats[J].J Neurotrauma,2017,34(3):707-719.
[52] 黄旭阳,王舒涵,韩冬,等.追风透骨胶囊对脊髓损伤模型大鼠脊髓神经细胞凋亡的影响及其机制研究[J].实用药物与临床,2018,21(10):1105-1108.
[53] 程田,闫立言,韩萧男,等.姜黄素通过Wnt/β-连环蛋白信号通路对脊髓损伤小鼠的神经保护作用[J].中华实验外科杂志,2021,38(5):894-896.