[1]赵长伟 王国臣 安璐 刘浪 雷雨擎 赵文海△.吉林地区围绝经期膝骨性关节炎人群中医体质的相关因素分析[J].中国中医骨伤科杂志,2022,30(03):17-20.
　ZHAO Changwei WANG Guochen AN Lu LIU LangLEI Yuqing ZHAO Wenhai.Related Factors Analysis for TCM Constitution in Perimenopausal Patients with Knee Osteoarthritis in Jilin[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2022,30(03):17-20.
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吉林地区围绝经期膝骨性关节炎人群中医体质的相关因素分析()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第30卷
期数:
2022年03期
页码:
17-20
栏目:
临床研究
出版日期:
2022-03-15

文章信息/Info

Title:
Related Factors Analysis for TCM Constitution in Perimenopausal Patients with Knee Osteoarthritis in Jilin
文章编号:
1005-0205(2022)03-0017-04
作者:
赵长伟1 王国臣2 安璐2 刘浪2 雷雨擎2 赵文海1△
1长春中医药大学附属医院(长春,130021)2长春中医药大学
Author(s):
ZHAO Changwei1 WANG Guochen2 AN Lu2 LIU Lang2LEI Yuqing2 ZHAO Wenhai1△
1Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130021, China; 2Changchun University of Chinese Medicine, Changchun 130021, China.
关键词:
围绝经期;  膝骨性关节炎;  中医体质;  危险因素;  规律分析
Keywords:
perimenopause;  knee osteoarthritis;  TCM constitution;  risk factors;  regular analysis
分类号:
R684.3
文献标志码:
A
摘要:
目的:系统分析围绝经期膝骨性关节炎人群中医体质与相关风险因素。方法:采用随机抽签现场面访法,选取围绝经期女性患者352例,通过调查问卷与体质辨识,并对年龄、体质量指数、文化程度及中医体质等进行分析。结果:年龄、体质量指数、文化程度、平和质、气虚质、阳虚质、阴虚质、痰湿质、湿热质、血瘀质、气郁质为影响围绝经期女性膝骨性关节炎发生的因素; 围绝经期女性膝骨性关节炎发病的独立危险因素为年龄、体质量指数、文化程度、气虚质、气郁质、阴虚质、阳虚质; 围绝经期女性膝骨性关节炎的保护性因素为平和质。结论:吉林地区围绝经期女性膝骨性关节炎人群多以气虚质、气郁质、阴虚质、阳虚质为独立危险因素,且与年龄、文化程度、体质量指数密切相关。
Abstract:
Objective:To analyze the TCM constitution and related risk factors of perimenopausal knee osteoarthritis systematically.Methods:A total of 352 cases of perimenopausal female patients were randomly selected by on-site interview.Age, body mass index, education level and TCM constitution were analyzed through questionnaire and physical identification.Results:Age, body mass index, education level, peace quality, Qi-deficiency quality, Yang-deficiency quality, Yin-deficiency quality, phlegm-dampness quality, damp-heat quality, blood stasis quality and Qi-stagnation quality were the factors influencing the occurrence of knee osteoarthritis in perimenopausal women.The independent risk factors for knee osteoarthritis in perimenopausal women were age, body mass index, education level, Qi-deficiency, Qi-stagnation, Yin-deficiency and Yang-deficiency.The protective factor of knee osteoarthritis in perimenopausal women was placidosis.Conclusion:Qi-deficiency, Qi-stagnation, Yin-deficiency and Yang-deficiency were the independent risk factors for knee osteoarthritis in perimenopausal women in Jilin, and were closely related to age, education level and body mass index.

参考文献/References:

[1] 中华医学会骨科学分会关节外科学组.骨关节炎诊疗指南(2018年版)[J].中华骨科杂志,2018,38(12):705-715.
[2] SALVE H,GUPTA V,PALANIVEL C,et al.Prevalence of knee osteoarthritis amongst perimenopausal women in an urban resettlement colony in South Delhi[J].Indian J Public Health,2010,54(3):155-157.
[3] SUN X,ZHEN X,HU X,et al.Osteoarthritis in the middle-aged and elderly in china:prevalence and influencing factors[J].International Journal of Environmental Research and Public Health,2019,16(23):4701.
[4] 梁比记,陈志强,周枭,等.不同中医证型围绝经期膝骨关节炎的X线表现及IL-1、TNF-α、E2 水平的比较[J].广东医学,2018,39(16):2513-2534.
[5] 叶超,陈婧,刘向春,等.不同证候膝骨关节炎患者证候程度评分与关节液炎性指标的典型相关分析[J].中国中医骨伤科杂志,2021,29(3):17-20.
[6] 黄明辉,宋进良,陈彦军,等.膝骨性关节炎(骨痹)患者中医体质与临床证型的调查研究[J].世界中医药,2017,12(7):1580-1586.
[7] 中华医学会骨科学分会.中医骨伤科临床诊疗指南·膝痹病(膝骨性关节炎)[J].康复学报,2019,29(3):1-7.
[8] 中华中医药学会.中医体质分类与判定(ZYYXH/T157-2009)[J].世界中西医结合杂志,2009,4(4):303-304.
[9] LOESER R F,COLLINS J A,DIEKMAN B O.Ageing and the pathogenesis of osteoarthritis.Nat Rev Rheumatol[J].Nat Rev Rheumatol,2016,12(7):412-420.
[10] 刘芳,黄俊山,魏海茵,等.围绝经期综合征患者性激素水平与体质学说阴虚质、气郁质关系研究[J].中国临床研究,2015,7(18):98-100.
[11] LAVOCAT F,OSTA B,MIOSSEC P.Increased sensitivity of rheumatoid synoviocytes to Schnurri-3 expression in TNF-α and IL-17A induced osteoblastic differentiation[J].Bone,2016,87:89-96.
[12] 李盛华,周明旺,潘文,等.阳虚质膝骨性关节炎软骨组织Sox9、Col2al基因表达的研究[J].西部中医药,2016,29(12):1-4.
[13] 周明旺,王小萍,李盛华,等.膝关节骨性关节炎患者中医体质类型与血清转化生长因子TGF-β1表达水平的相关性[J].中国中医药信息杂志,2016,29(12):1-4.
[14] 肖延成,王培民,徐波,等.异常代谢网络调控膝骨关节炎的研究进展[J].中国中医骨伤科杂志,2019,27(6):79-82.
[15] 何栩,罗小兵,虞亚明,等.中老年女性膝骨关节炎患者中医体质类型与膝股四头肌肌力、身体骨骼肌含量的相关性分析[J].四川中医,2017,35(9):39-41.

备注/Memo

备注/Memo:
基金项目:国家中医药管理局天池伤科流派工作室建设项目(第二轮建设)国家重点研发计划项目(2019YFC1709905)吉林省发展和改革委员会产业技术研究与开发项目(2020C033-6)
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更新日期/Last Update: 1900-01-01