[1]木定海,杜祖耀,林祥宋.补肾活血汤联合中药蜡疗治疗绝经后肾虚血瘀型膝骨关节炎[J].中国中医骨伤科杂志,2022,30(01):35-38+44.
　MU Dinghai,DU Zuyao,LIN Xiangsong.Clinical Study of Bushen Huoxue Decoction Combined with Chinese Herbal Wax Therapy on the Treatment of Postmenopausal Knee Osteoarthritis of Kidney Deficiency and Blood Stasis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2022,30(01):35-38+44.
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补肾活血汤联合中药蜡疗治疗绝经后肾虚血瘀型膝骨关节炎()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第30卷
期数:
2022年01期
页码:
35-38+44
栏目:
临床研究
出版日期:
2022-01-15

文章信息/Info

Title:
Clinical Study of Bushen Huoxue Decoction Combined with Chinese Herbal Wax Therapy on the Treatment of Postmenopausal Knee Osteoarthritis of Kidney Deficiency and Blood Stasis
文章编号:
1005-0205(2022)01-0035-04
作者:
木定海1; 杜祖耀1; 林祥宋1
1浙江瑞安市中医院(浙江 温州,325200)
Author(s):
MU Dinghai1; DU Zuyao1; LIN Xiangsong1
1Ruian Hospital of Traditional Chinese Medicine,Wenzhou 325200,Zhejiang China.
关键词:
补肾活血汤;  中药蜡疗;  绝经后;  肾虚血瘀型;  膝骨关节炎
Keywords:
Bushen Huoxue decoction;  Chinese herbal wax therapy;  postmenopausal;  kidney deficiency and blood stasis type;  knee osteoarthritis
分类号:
R684.3
文献标志码:
A
摘要:
目的:观察补肾活血汤联合中药蜡疗治疗绝经后肾虚血瘀型膝骨关节炎的临床有效性。方法:选取2020年3月至2021年3月接受治疗的绝经后膝骨关节炎患者64例,将其随机分为治疗组(32例)和对照组(32例)。治疗组使用补肾活血汤并联合中药蜡疗,治疗1个月,并记录其治疗15 d后和治疗30 d后的WOMAC评分; 对照组使用塞来昔布胶囊,治疗1个月,同样记录其治疗15 d后和治疗30 d后的WOMAC评分。采用膝关节功能量表WOMAC及《中医病证诊断疗效标准》来评估两组临床症状改善情况,并对其疗效进行评定。结果:治疗15 d后及治疗30 d后统计的WOMAC评分,相较于治疗前的数值有明显的降低,且治疗组的WOMAC数值降低幅度大于对照组。经《中医病证诊断疗效标准》疗效分析,治疗组有效率大于对照组。结论:补肾活血汤联合中药蜡疗在绝经后肾虚血瘀型膝骨关节炎的治疗中疗效显著,能很好地改善绝经后肾虚血瘀型膝骨关节炎的临床症状。
Abstract:
Objective:To observe the clinical efficacy of Bushen Huoxue decoction combined with traditional Chinese medicine wax therapy on the treatment of postmenopausal knee osteoarthritis of kidney deficiency and blood stasis.Methods:64 patients with postmenopausal knee osteoarthritis treated from March 2020 to March 2021 were selected and randomly divided into experimental group(32 cases)and control group(32 cases).The experimental group was given Bushen Huoxue decoction combined with Chinese herbal wax therapy for 1 month,and the WOMAC value after 15 d and 30 d of treatment were recorded respectively.The control group was given celecoxib capsules for 1 month,and the WOMAC value after 15 d and 30 d of treatment also were recorded.The WOMAC and TCM diagnosis and treatment of disease standard were used to evaluate the improvement of clinical symptoms in the two groups,and the efficacy was assessed.Results:The values of WOMAC after treatment of 15 d and 30 d were significantly lower than those before treatment,and the experimental group's WOMAC was more decreased than that of the control group.The effective rate of experimental group was higher than that in control group according to the efficacy analysis of TCM diagnosis and treatment of disease standard.Conclusion:Bushen Huoxue decoction combined with traditional Chinese medicine wax therapy has a significant efficacy on the treatment of postmenopausal knee osteoarthritis of kidney deficiency and blood stasis,and can well improve the clinical symptoms of postmenopausal knee osteoarthritis of kidney deficiency and blood stasis.

参考文献/References:

[1] TANG X,WANG S F,ZHAN S Y,et al.The prevalence of symptomatic knee osteoarthritis in China:results from the china health and retirement longitudinal study[J].Arthritis & Rheumatology,2016,68(3):648-653.
[2] 刘亚平,杜凯月,郭洪敏,等.绝经后女性膝骨关节炎性激素水平及其与年龄 和病变程度的关系[J].实用骨科杂志,2018,24(2):139-152.
[3] 王欢,孙贺,张耀南,等.中国40岁以上人群原发性膝骨关节炎各间室患病状况调查[J].中华骨与关节外科杂志,2019,12(7):528-532.
[4] DAI Z L,NIU J B,ZHANG Y Q,et al.Dietary intake of fibre and risk of knee osteoarthritis in two US prospective cohorts[J].Annals of the Rheumatic Diseases,2017,76(8):1411-1419.
[5] 郑陶,许治国,许志宇,等.补肾活血方治疗膝骨关节炎临床疗效[J].中华中医药学刊,2019,37(6):1506-1509.
[6] 林巧璇,刘晶,卢莉铭,等.补肾活血汤对骨质疏松性椎体压缩性骨折PKP术后患者疼痛和骨代谢的影响[J].中国中医骨伤科杂志,2021,29(3):21-26.
[7] 许怀来,徐凡平,黄明华,等.中医外治法治疗膝骨关节炎的研究进展[J].中国中医骨伤科杂志,2018,26(11):85-88.
[8] 中华医学会骨科学分会.骨关节炎诊治指南(2007年版)[J].中国矫形外科杂志,2014,22(3):287-288.
[9] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:30-49.
[10] KELLGREN J H,LAWRENCE J S.Radiological assessment of osteo-arthrosis[J].Ann Rheum Dis,1957,16(4):494-502.
[11] 中国中西医结合学会骨伤科专业委员会.膝骨关节炎中西医结合诊疗指南[J].中华医学杂志,2018,98(45):3653-3657.
[12] 熊应宗,朱俊琛,王超,等.针刀联合塞来昔布治疗膝骨关节炎的临床疗效观察[J].中国中医骨伤科杂志,2020,28(2):19-23.
[13] PONKILAINEN V T,H?KKINEN A H,UIMONEN M M,et al.Validation of the Western Ontario and McMaster Universities Osteoarthritis Index in patients having undergone ankle fracture surgery[J].The Journal of Foot and Ankle Surgery,2019,58(6):1100-1107.
[14] 张正付,李萌,燕娟,等.药物临床试验中不良事件的案例收集与评判[J].中国临床药理学杂志,2020,36(23):3957-3961.
[15] CECIL R L,ARCHER B H.Classfication and treatment and chronic arthritis[J].The Journal of the American Medical Association,1926,87:741-746.
[16] 周逸敏,邱友利,张俐.膝骨关节炎合并骨质疏松症大鼠模型的建立与评估[J].中国中医骨伤科杂志,2017,25(9):1-4.
[17] 吴玖斌,李蒙,谢雁鸣,等.膝关节骨性关节炎当代中医学术团队研究[J].北京中医药大学学报,2016,39(6):518.
[18] 彭莎,姚楠,卢岩岩,等.补肾强筋胶囊对膝骨关节炎的治疗作用及分子机制研究[J].中国中医骨伤科杂志,2021,29(4):13-19.
[19] 牛彦强,颜春鲁,安方玉,等.膝骨关节炎基因表达及中医药干预机制的研究进展[J].中国骨质疏松杂志,2020,26(4):585-589.
[20] 卢敏,蒋梁,段航.基于瘀祛新生理论治疗膝骨关节炎的理论研究[J].中医正骨,2019,31(1):23-25.
[21] 王晶,闻锐.中药蜡疗止痛技术治疗风寒湿痹型类风湿关节炎的临床疗效及对血清MMP-3、OPG及RANKL的影响[J].中华中医药学刊,2018,36(8):1868-1871.
[22] 范惠霞,樊志丽,朱炜.中药蜡疗、熏蒸联合西药治疗膝骨关节炎临床研究[J].新中医,2021,53(10):76-80.
[23] 郭凤红,范鹏,张逊,等.蜡疗临床应用新进展[J].中华全科医学,2018,16(3):465-483.
[24] 叶海霞,温晓文,童艳青.中药蜡疗联合常规疗法与护理措施干预早中期膝关节骨性关节炎临床研究[J].新中医,2020,52(2):165-168.

更新日期/Last Update: 2022-01-18