[1]许岳 戴小宇△ 应璞 周烨 路通 薛燚 王强.膝关节骨性关节炎患者血脂与行全膝关节置换术后下肢深静脉血栓的相关性研究[J].中国中医骨伤科杂志,2021,29(05):38-42.
　XU Yue DAI Xiaoyu YING Pu ZHOU Ye LU Tong XUE Yi WANG Qiang.Correlation between Blood Lipid and DVT of LowerExtremities after TKA in Patients with KOA[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2021,29(05):38-42.
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膝关节骨性关节炎患者血脂与行全膝关节置换术后下肢深静脉血栓的相关性研究()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第29卷
期数:
2021年05期
页码:
38-42
栏目:
临床研究
出版日期:
2021-05-15

文章信息/Info

Title:
Correlation between Blood Lipid and DVT of LowerExtremities after TKA in Patients with KOA
文章编号:
1005-0205(2021)05-0038-05
作者:
许岳1 戴小宇2△ 应璞1 周烨1 路通1 薛燚1 王强1
1南京中医药大学常熟附属医院(江苏 常熟,215500)2常州市第一人民医院骨科
Author(s):
XU Yue1 DAI Xiaoyu2△ YING Pu1 ZHOU Ye1 LU Tong1 XUE Yi1 WANG Qiang1
1Changshu Affiliated Hospital to Nanjing University of Chinese Medicine,Changshu 215500,Jiangsu China; 2The First People’s Hospital of Changzhou,Changzhou 213000,Jiangsu China.
关键词:
血脂;  骨性关节炎;  全膝关节置换术;  深静脉血栓
Keywords:
blood lipid;  osteoarthritis;  total knee arthroplasty;  deep vein thrombosis
分类号:
R684.3
文献标志码:
A
摘要:
目的:分析原发性膝关节骨性关节炎(KOA)患者术前血脂水平与全膝关节置换(TKA)术后下肢深静脉血栓(DVT)发生风险的潜在相关性。方法:纳入从2013年8月至2020年1月因原发性KOA行TKA的患者共431例,所有患者均在术后第3天行双下肢静脉B超。根据检查结果分为DVT组(男14例,女81例,平均年龄67.36岁)和非DVT组(男68例,女268例,平均年龄68.25岁),通过多变量Logistic回归分析两组患者血清甘油三酯(TG),总胆固醇(TC),高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A1、载脂蛋白B水平与术后DVT的相关性。结果:女性KOA患者中,DVT组LDL-C值明显高于非DVT组(P=0.043),且高LDL-C值与DVT的发生风险增加显著相关(P=0.037)。结论:高LDL-C水平是女性原发性KOA患者行TKA术后DVT发生的危险因素。
Abstract:
To analyze the potential correlation between the preoperative lipid level of patients with primary knee osteoarthritis(KOA)and the risk of deep vein thrombosis(DVT)after total knee arthroplasty(TKA).Methods:431 patients who has undergone TKA for primary KOA from August 2013 to January 2020 were included into this study,and all patients received bilateral lower limb vein B-ultrasound on the 3rd day after the operation.The patients were divided into DVT group(14 males and 81 females with an average age of 67.36 years old)and non-DVT group(68 males and 268 females with an average age of 68.25 years old)according to the examination results.The correlation of levels of triglyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),Apolipoprotein A1 and Apolipoprotein B with postoperative DVT were analyzed by multivariate Logistic regression.Results:In female patients with KOA,LDL-C value in DVT group was significantly higher than that in non-DVT group(P=0.043),and high LDL-C value was significantly correlated with the increased risk of DVT(P=0.037).Conclusion:High LDL-C level is a risk factor for DVT after total knee arthroplasty in female patients with primary knee osteoarthritis.

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备注/Memo

备注/Memo:
基金项目:苏州市“科教兴卫”科技项目(KJXW202068)
△通信作者 E-mail:dxyiverson3@163.com
更新日期/Last Update: 2021-05-15