[1]吴荣蕾 何洁 王晓琼 祝雪花△ 方苏亭.隔药饼灸治疗膝关节骨性关节炎临床观察[J].中国中医骨伤科杂志,2021,29(04):32-34.
　WU Ronglei HE Jie WANG Xiaoqiong ZHU Xuehua FANG Suting.Clinical Observation of Herbal Cake-Separated Moxibustion inTreatment of Patients with Knee Osteoarthritis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2021,29(04):32-34.
点击复制

隔药饼灸治疗膝关节骨性关节炎临床观察()
分享到：

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第29卷
期数:
2021年04期
页码:
32-34
栏目:
临床研究
出版日期:
2021-04-15

文章信息/Info

Title:
Clinical Observation of Herbal Cake-Separated Moxibustion inTreatment of Patients with Knee Osteoarthritis
文章编号:
1005-0205(2021)04-0032-03
作者:
吴荣蕾1; 2 何洁2 王晓琼2 祝雪花1△ 方苏亭3
1浙江中医药大学(杭州,310053)
2浙江瑞安市中医院重症医学科
3台州博爱医院骨科
Author(s):
WU Ronglei1; 2 HE Jie2 WANG Xiaoqiong2 ZHU Xuehua1△ FANG Suting3
1Zhejiang University of Traditional Chinese Medicine,Hangzhou 310053,China; 2Traditional Chinese Medicine Hospital of Ruian City,Ruian 325200,Zhejiang China; 3Department of Orthopaedics,Taizhou Boai Hospital,Taizhou 318000,Zhejiang China.
关键词:
隔药饼灸;  膝关节骨性关节炎;  骨关节炎指数;  临床疗效
Keywords:
medicinal cake moxibustion;  knee osteoarthritis pain;  osteoarthritis index;  clinical efficacy
分类号:
R684.3
文献标志码:
A
摘要:
目的:观察隔药饼灸治疗膝关节骨性关节炎的有效性、安全性。方法:我院2015年1月至2017年1月收治的80例膝关节骨性关节炎患者按随机数字表法分入两组。对照组(40例)给予双氯芬酸钠缓释片治疗,观察组(40例)给予隔药饼灸治疗,观察并比较两组患者临床疗效、WOMAC骨关节炎指数、VAS评分以及不良反应的具体情况。结果:观察组患者治疗后临床总有效率显著高于对照组(97.50%对85.00%),差异有统计学意义(χ2=3.914,P=0.048); 治疗前,观察组与对照组WOMAC骨关节炎指数比较差异无统计学意义(P>0.05); 治疗第1、2、3、4周,两组患者WOMAC骨关节炎指数均较治疗前显著降低,且观察组低于对照组,差异有统计学意义(t=2.282,P=0.023; t=2.889,P=0.005; t=3.846,P<0.001; t=5.509,P<0.001); 治疗前,观察组与对照组VAS评分比较差异无统计学意义(P>0.05); 治疗后,两组患者VAS评分均较治疗前显著降低,且观察组低于对照组,差异有统计学意义(t=3.462,P<0.001); 观察组不良反应发生率低于对照组,差异有统计学意义(2.50%对15.00%; χ2=3.914,P=0.048)。结论:隔药饼灸治疗对膝关节骨性关节炎具有良好的临床疗效,能明显改善患者骨关节炎指数以及VAS评分,且安全性高,值得进一步推广应用。
Abstract:
To observe the efficacy and safety of herbal cake separated moxibustion in the treatment of knee osteoarthritis.Methods:80 patients with knee osteoarthritis from January 2015 to January 2017 were randomly divided into control group and study group(40 cases in each group)according to random number table method.The cases in the control group were treated with diclofenac sodium sustained-release tablets,while the cases in the study group were treated with cake-separated moxibustion.The clinical efficacy,WOMAC osteoarthritis index,VAS score and adverse reactions of the two groups were observed and compared.Results:The total clinical effective rate of the study group was significantly higher than that of the control group(97.50% vs 85.00%; χ2=3.914,P=0.048).Before treatment,there was no significant difference in WOMAC Osteoarthritis Index between the study group and the control group(P>0.05).After treatment for 1,2,3 and 4 weeks,the WOMAC Osteoarthritis Index of the study group and the control group were significantly higher than that before treatment,and the degree of reduction in the study group was higher than that in the control group(t=2.282,P=0.023; t=2.889,P=0.005; t=3.846,P<0.001; t=5.509,P<0.001).Before treatment,there was no significant difference in the VAS score between the study group and the control group(P>0.05).After treatment,the VAS score in the study group and the control group was significantly lower than that before treatment,and the VAS score in the study group was lower than that in the control group(t=3.462,P<0.001).The incidence of adverse reactions in the study group was lower than that in the control group(2.50% vs 15.00%; χ2=3.914,P=0.048).Conclusion:Medicinal cake moxibustion has good clinical efficacy for knee osteoarthritis patients.It can significantly improve the patients’ Osteoarthritis Index and VAS score,and has high safety,which is worthy of further promotion and application.

参考文献/References:

[1] 邬波,柳椰,马旭,等.壮骨片治疗肝肾亏虚型膝关节骨性关节炎的临床研究[J].中国中医骨伤科杂志,2019,27(10):35-38.
[2] 葛国芬,俞霞,章春红,等.复方透海散熏蒸治疗膝关节骨性关节炎的疗效观察及其对血清TNF-α、IL-6水平的影响[J].中国中医药科技,2017,20(9):544-546.
[3] 郑斌,梅伟,魏成建,等.中医治疗膝骨关节炎研究进展[J].湖北中医药大学学报,2016,18(2):114-117.
[4] 陆斌,李建武,杨艳,等.臭氧联合玻璃酸钠对膝关节骨性关节炎患者膝关节功能及疼痛症状的改善效果观察[J].临床和实验医学杂志,2018,17(11):70-73.
[5] 陈美仁,胡蓉,林健,等.隔附子饼灸治疗肾虚髓亏型膝关节骨性关节炎疗效观察[J].中国针灸,2018,38(1):45-49.
[6] 中华医学会骨科学分会.骨关节炎诊治指南(2007年版)[J].中华关节外科杂志(电子版),2007,1(4):287-291.
[7] 杨志奎,代加楠,曹熙,等.血尿酸对膝骨关节炎患者WOMAC指数变化的影响研究[J].实用骨科杂志,2017,23(1):28-31.
[8] 熊应宗,朱俊琛,王超,等.针刀联合塞来昔布治疗膝骨关节炎的临床疗效观察[J].中国中医骨伤科杂志,2020,28(2):19-23.
[9] 国家药品监督管理局.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:87-89.
[10] CARLESSO L C, NEOGI T.Identifying pain susceptibility phenotypes in knee osteoarthritis[J].Clin Exp Rheumatol,2019,120(5):96-99.
[11] PIUZZI N S, NG M, KANTOR A,et al.What is the price and claimed efficacy of platelet-rich plasma injections for the treatment of knee osteoarthritis in the united States?[J].J Knee Surg,2019,32(9):879-885.
[12] 郑伟康,张宏,王旭昀,等.中医药治疗膝骨关节炎研究进展[J].山西医药杂志,2018,47(9):1013-1016.
[13] 喻淑珍,曾虹丹.益肾宣痹汤配合西医疗法治疗膝骨性关节炎的效果及对炎症因子的影响[J].中国地方病防治杂志,2018,33(6):107-108.
[14] 黄丽强,季蓉.雷火灸对膝关节骨性关节炎患者VAS、WOMAC评分影响的临床研究[J].江苏中医药,2017,5(8):57-58.

备注/Memo

备注/Memo:
基金项目:浙江省医药卫生科技计划项目(2017KY716)
△通信作者 E-mail:snow_zxh@163.com
更新日期/Last Update: 2021-04-15