[1]王雷 邢祯全.恒古骨伤愈合剂联合玻璃酸钠治疗膝关节骨关节炎的疗效分析[J].中国中医骨伤科杂志,2021,29(03):59-61.
 WANG Lei XING Zhenquan.Efficacy Analysis for Henggu Bone Wound Healing Agent Combined with Sodium Hyaluronate in the Treatment of Knee Osteoarthritis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2021,29(03):59-61.
点击复制

恒古骨伤愈合剂联合玻璃酸钠治疗膝关节骨关节炎的疗效分析()
分享到:

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第29卷
期数:
2021年03期
页码:
59-61
栏目:
临床报道
出版日期:
2021-03-15

文章信息/Info

Title:
Efficacy Analysis for Henggu Bone Wound Healing Agent Combined with Sodium Hyaluronate in the Treatment of Knee Osteoarthritis
文章编号:
1005-0205(2021)03-0059-03
作者:
王雷 邢祯全
1海南三亚市人民医院脊柱关节外科(海南 三亚,572000)通信作者 E-mail:laogao12@189.cn
Author(s):
WANG Lei XING Zhenquan
1Department of Spine and Joint Surgery,Sanya People’s Hospital,Sanya 572000,Hainan China.
关键词:
膝关节骨关节炎 玻璃酸钠 恒古骨伤愈合剂 退行性病变 关节腔注射
Keywords:
knee osteoarthritis sodium hyaluronate Henggu bone wound healing agent degenerative disease injection in the joint
分类号:
R684.3
文献标志码:
B
摘要:
目的:探讨恒古骨伤愈合剂联合玻璃酸钠治疗KL2/3级膝关节骨关节炎的疗效。方法:选取KL2/3级膝关节骨关节炎患者50例,给予玻璃酸钠关节腔注射加口服恒古骨伤愈合剂治疗。结果:治疗5周后,治疗总有效率为 96%,患者治疗后的疼痛视觉模拟(VAS)评分下降,Lysholm膝关节功能评分增高,与治疗前比较效果优良。结论:恒古骨伤愈合剂结合玻璃酸钠治疗膝关节骨关节炎能够有效缓解患者的疼痛,提升膝关节功能,提高治疗效果。
Abstract:
To investigate the efficacy of Henggu bone wound healing agent combined with sodium hyaluronate in the treatment of KL2/3 knee osteoarthritis.Methods:50 patients with knee osteoarthritis of KL2/3 degree were selected and treated with sodium hyaluronate injection in the joint cavity and oral taken Henggu bone healing agent.Results:The total effective rate of treatment was 96% after 5 weeks of treatment.The patient’s VAS(visual analogue scales)score decreased,and Lysholm score increased after treatment.The effect was better than that before treatment.Conclusion:Henggu bone wound healing agent combined with sodium hyaluronate in the treatment of knee osteoarthritis can effectively relieve the pain,improve knee joint function and enhance therapeutic effect.

参考文献/References:

[1] DEVEZA L A,KRAUS V B,COLLINS J E,et al.Is synovitis detected on non-contrast-enhanced magnetic resonance imaging associated with serum biomarkers and clinical signs of effusion data from the osteoarthritis initiative?[J].Scandinavian Journal of Rheumatology,2018,47(3):235-242.
[2] TURAJANE T,AMPHANSAP T,LABPIBOONPONG V,et al.Total knee replacement following repeated cycles of intra-articular sodium hyaluronate(500-730 Kda)in failed conservative treatment of knee osteoarthritis:a 54-month follow-up[J].Journal of the Medical Association of Thailand,2009,92(Suppl 6):S63-S68.
[3] 邬波,马旭,柳椰,等.膝关节骨关节炎患者软骨炎症因子表达与病变程度的相关性[J].中国组织工程研究,2020,24(2):236-241.
[4] 龚利,邵盛,李建华,等.名老中医手法治疗膝骨关节炎的经验荟萃[J].中国中医骨伤科杂志,2017,25(1):66-68.
[5] 中华医学会骨科分会.骨关节炎诊治指南(2007年版)[J].中华骨科杂志,2007,27(10):793.
[6] JENSEN M P,KAROLY P,BRAVER S.The measurement of clinic pain intensity:a comparison of six methods[J].Pain,1986,27(1):117-126.
[7] BIJLSMA J W,BERENBAUM F,LAFEBER F P.Osteoarthritis:an update with relevance for clinical practice[J].Lancet,2011,377(9783):2115-2126.
[8] XING D,GAO H,LIU Z,et al.Baicalin inhibits inflammatory responses to interleukin-1β stimulation in human chondrocytes[J].J Interferon Cytokine Res,2017,37(9):398-405.
[9] 周嵘,钱齐荣.软骨下骨在骨关节炎发病中作用的研究进展[J].中国矫形外科杂志,2014,22(21):1971-1973.
[10] FELSON D T.Clinical practice:osteoarthritis of the knee[J].N Engl J Med,2006,354(8):841-848.
[11] BOWDEN D J,BYRNE C A,ALKHAYAT A,et al.Injectable viscoelastic supplements:a review for radiologists[J].Am J Roentgenol,2017,209(4):883-888.
[12] 胡敏,王兵,赵宏斌,等.恒古骨伤愈合剂预防性给药对股骨颈骨折术后半年股骨头坏死发生率及负重髋疼痛程度的影响[J].中国临床康复,2005(14):158-159.
[13] LI G Y,YIN J M,GAO J J,et al.Subchondral bone in osteoarthritis:insight into risk factors and microstructural changes[J].Arthritis Research & Therapy,2013,15(6):223.
[14] JOSE J,PASQUOTTI G,SMITH M K,et al.Subchondral insufficiency fractures of the knee:review of imaging findings[J].Acta Radiol,2015,56(6): 714-719.
[15] 刘强,陈君长.重组转化因子Bl的表达及修复骨缺损的研究[J].中国骨伤,2000,13(12):715.
[16] 汤耿民,沈霖,涂意辉,等.补肾活血方对成骨细胞生长因子TGF-β1 mRNA表达的影响[J].中国中医骨伤科杂志,1999,7(5):7-9.
[17] 吴继昆.恒古骨伤愈合剂治疗157例骨关节炎疗效总结[J].中国现代药物应用,2018,12(24):196-197.

更新日期/Last Update: 2021-03-15