[1]李克嵩 巩勋 姜泉△ 王建 刘蔚翔 李延婷 翟争 刘岩.863例女性类风湿关节炎患者不同证候与相关指标关系探讨[J].中国中医骨伤科杂志,2020,28(10):10-12,16.
　LI Kesong GONG Xun JIANG Quan WANG Jian LIU Weixiang LI Yanting ZHAI Zheng LIU Yan.Study on the Relationship between Different Syndromes and Related Indexes in 863 Female Patients with Rheumatoid Arthritis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2020,28(10):10-12,16.
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863例女性类风湿关节炎患者不同证候与相关指标关系探讨()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第28卷
期数:
2020年10期
页码:
10-12,16
栏目:
临床研究
出版日期:
2020-10-10

文章信息/Info

Title:
Study on the Relationship between Different Syndromes and Related Indexes in 863 Female Patients with Rheumatoid Arthritis
文章编号:
1005-0205(2020)10-0010-03
作者:
李克嵩1 巩勋1 姜泉1△ 王建1 刘蔚翔1 李延婷1 翟争1 刘岩2
Author(s):
LI Kesong1 GONG Xun1 JIANG Quan1△ WANG Jian1 LIU Weixiang1 LI Yanting1 ZHAI Zheng1 LIU Yan2
1Guang'anmen Hospital,Chinese Academy of Traditional Chinese Medicine,Beijing 100053,China; 2Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China.
关键词:
类风湿关节炎;  女性患者;  炎性指标
Keywords:
rheumatoid arthritis;  female patients;  inflammatory index
分类号:
R684.3
文献标志码:
A
摘要:
目的:探讨女性类风湿关节炎(RA)患者不同证候与相关指标的关系。方法:采用横断面调查研究方法,分析全国18家研究中心女性RA患者的证型和实验室指标(PLT,HGB及ESR,CRP)的特点及关系。结果:纳入863例女性RA患者,湿热痹阻证占比最高(40.90%); PLT值组间比较差异有统计学意义(F=2.434,P=0.033),湿热痹阻证与寒湿痹阻证比较差异有统计学意义(P<0.05); HGB值组间比较差异有统计学意义(F=15.924,P<0.001),湿热痹阻证、肝肾不足证分别与其他证型比较差异有统计学意义(P<0.05); ESR值组间比较差异有统计学意义(F=2.821,P=0.016),湿热痹阻证与其他证型比较差异有统计学意义(P<0.05),风湿痹阻证与气血两虚证比较差异有统计学意义(P<0.05); CRP值组间比较差异无统计学意义(F=2.166,P=0.056)。结论:湿热痹阻证是女性RA的主要证型,RA活动期PLT,ESR及CRP均升高,HGB降低,与湿热痹阻证具有较高的相关性。
Abstract:
To explore the relationship between different syndromes and related indexes in female patients with rheumatoid arthritis(RA).Methods:The characteristics and relationship of syndrome types and laboratory indexes(PLT,HGB,ESR,CRP)of female RA patients in 18 research centers of China were analyzed by cross-sectional investigation.Results:There were 863 female RA patients with different syndrome types,the percentage of damp-heat obstruction syndrome was the highest(40.90%); there were significant differences in PLT values between the groups(F=2.434,P=0.033).The difference between damp heat syndrome and cold damp obstruction syndrome was statistically significant(P<0.05).The difference of HGB value between groups was statistically significant(F=15.924,P<0.001),there were significant differences between the syndrome of damp-heat obstruction and the syndrome of liver and kidney deficiency(P<0.05).The difference in ESR values was statistically significant(F=2.821,P=0.016),the difference between the damp-heat obstruction syndrome and other syndrome types was statistically significant(P<0.05),and the difference between the syndromes of dampness and the deficiency of Qi and blood was statistically significant(P<0.05).There was no significant difference in CRP between groups(F=2.166,P=0.056).Conclusion:Damp-heat obstruction syndrome is the main symptom of female RA.PLT,ESR and CRP in the active period of RA all increase,and HGB decrease,which has a high correlation with damp-heat obstruction syndrome.

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备注/Memo

备注/Memo:
(收稿日期:2020-04-12)基金项目:国家重点研发计划—中医药治疗类风湿关节炎的临 床队列及疗效评价研究(2018YFC1705202) 国家自然科学基金资助项目(81704063) 1中国中医科学院广安门医院(北京,100053) 2北京中医药大学东直门医院 △通信作者 E-mail:doctorjq@126.com
更新日期/Last Update: 2020-10-10