[1]黄中华 张淑云.糖化血红蛋白对全髋关节置换术后感染的影响[J].中国中医骨伤科杂志,2020,28(09):44-47.
　HUANG Zhonghua ZHANG Shuyun.Effect of Glycated Hemoglobin on Infection after Total Hip Arthroplasty[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2020,28(09):44-47.
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糖化血红蛋白对全髋关节置换术后感染的影响()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第28卷
期数:
2020年09期
页码:
44-47
栏目:
临床论著
出版日期:
2020-09-10

文章信息/Info

Title:
Effect of Glycated Hemoglobin on Infection after Total Hip Arthroplasty
文章编号:
1005-0205(2020)09-0044-04
作者:
黄中华1 张淑云1
1长沙市第四医院骨二科(长沙,410006)
Author(s):
HUANG Zhonghua1 ZHANG Shuyun1
1The Fourth Hospital of Changsha,Changsha 410006,China.
关键词:
糖化血红蛋白;  全髋关节置换术;  感染率;  糖尿病
Keywords:
glycated hemoglobin;  total hip arthroplasty;  infection rate;  diabetes
分类号:
R658.3
文献标志码:
A
摘要:
目的:探究糖化血红蛋白对全髋关节置换术后感染的影响。方法:选取本院2007年3月至2016年5月收治的2 444例进行初次全髋关节置换术患者的资料,按照糖化血红蛋白高低进行分组。将糖化血红蛋白在4%～6%之间的患者作为对照组,高于6.5%的患者作为研究组。统计两组患者在进行关节置换术后的感染率、手术后的切口愈合时间、入院时和术后6个月的健康状况,并使用SF-36量表进行评分及对比。结果:患者平均随访时间为(48±10)个月,研究组共575例患者,出现14个确诊感染病例,感染率为2.435%; 对照组共1 869例患者,出现12个确诊感染病例,感染率为0.642%。经SPSS软件分析,研究组患者的术后感染率明显高于对照组,两组间差异有统计学意义(P=0.021)。研究组平均切口愈合时间(19.876±6.403)d,对照组平均切口愈合时间(10.221±3.135)d,研究组患者的切口愈合时间明显高于对照组,两组间差异有统计学意义(P=0.030)。研究组患者入院时SF-36量表平均评分(86.903±7.981),对照组患者入院时SF-36量表平均评分(95.415±10.827),两组间差异无统计学意义(P=0.152); 研究组术后6个月SF-36量表平均评分(107.303±6.516),对照组术后6个月SF-36量表平均评分(126.889±8.733),两组间差异有统计学意义(P=0.011)。研究组患者术后6个月的SF-36量表评分明显低于对照组。结论:对于进行关节置换手术的患者来说,糖化血红蛋白高于6.5%,患者术后感染的概率明显增加,切口愈合时间明显延长,术后身体健康情况不佳,因此,进行关节置换手术的病人一定要严格控制血糖和糖化血红蛋白水平。
Abstract:
Objective:To investigate the effect of glycated hemoglobin on infection after total hip arthroplasty.Methods:The data of 2 444 patients who underwent the first total hip arthroplasty in our hospital from March 2007 to May 2016 were retrospectively analyzed and divided into two groups according to the level of glycated hemoglobin.Patients with glycated hemoglobin between 4%～6% were regarded as the control group,and patients higher than 6.5% were regarded as the study group.The infection rates of patients in the two groups after artificial joint replacement were documented and compared.The wound healing time after surgery was compared.The health status of the two groups at the time of admission and 6 months after surgery were calculated and SF-36 scales were scored and compared.Results:The average follow-up time of patients was(48±10)months.A total of 575 patients in the study group had 14 confirmed infections with an infection rate of 2.435%.The control group had a total of 1 869 patients with 12 confirmed infections with the infected rate of 0.642%.The postoperative infection rate of patients in the study group was significantly higher than that in the control group(P=0.021).The average incision healing time in the study group was(19.876±6.403)d,and the average incision healing time in the control group was(10.221±3.135)d(P=0.030).The average score of the SF-36 scale was 86.903±7.981 when the patients in the study group were admitted,and the average score of the SF-36 scale was 95.415±10.827 when the patients in the control group were admitted.There was no statistical difference between the two groups(P=0.152).The average score of the SF-36 scale was 107.303±6.516,and the average score of the SF-36 scale in the control group 6 months after operation was 126.889±8.733.There was a statistical difference between the two groups.The SF-36 scale score of the study group patients in 6 months after operation was significantly lower than that of the control group(P=0.011).Conclusion:The glycated hemoglobin of patientis higher than 6.5%,which is likely to significantly increase the probability of postoperative infection,the healing time and effect the postoperative physical health.Therefore blood glucose and glycated hemoglobin levels need to be reasonably controlled for artificial joint replacement patients.

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备注/Memo

备注/Memo:
(收稿日期:2019-11-04)
更新日期/Last Update: 2020-09-10