[1]史长龙 孟州令 刘劲松 张威 吕光 王建楠 郭长青 邵帮伟 李路广△ 张学思.改良型双乌祛痛膏治疗急性踝关节扭伤的疗效观察[J].中国中医骨伤科杂志,2020,28(08):26-30.
　SHI Changlong MENG Zhouling LIU Jingsong ZHANG Wei LYN Guang WANG Jiannan GUO Changqing SHAO Bangwei LI Luguang ZHANG Xuesi.Effect of Modified Shuangwu Qutong Ointment on Acute Ankle Sprain[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2020,28(08):26-30.
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改良型双乌祛痛膏治疗急性踝关节扭伤的疗效观察()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第28卷
期数:
2020年08期
页码:
26-30
栏目:
临床研究
出版日期:
2020-08-10

文章信息/Info

Title:
Effect of Modified Shuangwu Qutong Ointment on Acute Ankle Sprain
文章编号:
1005-0205(2020)08-0026-05
作者:
史长龙1 孟州令2 刘劲松1 张威1 吕光3 王建楠3 郭长青3 邵帮伟3 李路广1△ 张学思2
1中国中医科学院望京医院(北京,100102) 2北京中医药大学 3河北固安县中医院骨科联合病房
Author(s):
SHI Changlong1△ MENG Zhouling2 LIU Jingsong1 ZHANG Wei1 LYN Guang3 WANG Jiannan3 GUO Changqing3 SHAO Bangwei3 LI Luguang1 ZHANG Xuesi2
1Wangjing Hospital,China Academy of Chinese Medical Sciences,Beijing 100102,China; 2Beijing University of Chinese Medicine,Beijing 100029,China; 3Combined Orthopedic Ward of Gu'an Hospital of Traditional Chinese Medicine,Langfang 065500,Hebei China.
关键词:
改良型双乌祛痛膏;  氮酮;  急性踝关节扭伤;  疗效观察
Keywords:
modified Shuangwu Qutong ointment;  azone;  acute ankle sprain;  curative effect observation
分类号:
R684.7
文献标志码:
A
摘要:
目的:观察改良型双乌祛痛膏治疗急性踝关节扭伤的临床疗效。方法:选取急性踝关节扭伤患者120例,采用随机数字表法随机分为A组(改良型双乌祛痛膏)和B组(双乌祛痛膏)和C组(冰敷联合扶他林软膏)。每组各40例,疗程14 d,1个月后随访。对三组患者治疗前、第7天、第14天及随访期的VAS,AOFAS踝-后足评分及临床疗效进行比较。结果:治疗后和随访期三组的VAS及AOFAS踝-后足评分与治疗前差异均有统计学意义(P<0.017)。治疗后第7天VAS及AOFAS踝-后足评分比较,A和B组分别与C组差异均有统计学意义(P<0.05),A组与B组差异无统计学意义(P>0.05)。治疗后第14天VAS及AOFAS踝-后足评分比较,三组间两两比较差异均有统计学意义(P<0.05)。随访期三组间VAS评分两两比较差异无统计学意义(P>0.05),随访期AOFAS踝-后足评分比较,A和B组分别与C组比较,差异均无统计学意义(P>0.05),A组与C组比较差异有统计学意义(P<0.05)。治疗14 d后三组间的临床疗效两两比较,差异均有统计学意义(P<0.017); 随访期A和C组分别与B组的临床疗效两两比较,差异均无统计学意义(P>0.017),A与C组的临床疗效比较差异有统计学意义(P<0.017)。结论:改良型双乌祛痛膏治疗急性踝关节扭伤,在缓解疼痛和恢复踝关节功能等方面疗效更显著,安全性好,随访期疗效更稳定。
Abstract:
Objective:To observe the clinical efficacy of modified Shuangwu Qutong ointment on the treatment of acute ankle sprain. Methods:120 patients with acute ankle sprain were randomly divided into group A(modified Shuangwu Qutong ointment),group B(Shuangwu Qutong ointment),group C(ice application combined with Futalin ointment)with 40 cases in each group. The course of treatment was 14 d with followed up one month later. The VAS,AOFAS scores and clinical efficacy of the three groups were documented before treatment and the 7th,14th and 30th day after treatment. Results:There were significant differences in VAS and AOFAS scores between the three groups after treatment and before treatment(P<0.017).There were significant differences in VAS and AOFAS scores between group A and group B and group C 7 d after treatment(P<0.05),but there was no significant difference between group A and group B(P>0.05). There were significant differences in VAS and AOFAS scores among three groups on the 14th day after treatment(P<0.05). During the follow-up period,there was no significant difference in VAS score between the two groups(P>0.05),and no significant difference in AOFAS score was found among group A and C(P>0.05),and there was significant difference between group A and group C(P<0.05).There was statistically significant difference in clinical efficacy between each two groups(P<0.017),during the follow-up period,there was no significant difference between A,B and C groups(P>0.017),and there was statistically significant difference in clinical efficacy between group A and C(P<0.017). Conclusion:The improved Shuangwu Qutong ointment is more effective and safe on the treatment of acute ankle sprain in the aspects of pain relief and ankle function recovery,and has more stable effect in the follow-up period.

参考文献/References:

[1] 张如云,张奇,杨宗酉,等.成人踝关节损伤的流行病学分析[J]. 中国骨科临床与基础研究杂志,2014,6(3):139-143.
[2] PETERSEN W,REMBITZKI I V,KOPPENBURG A G,et al. Treatment of acute ankle ligament injuries:a systematic review[J]. Archives of Orthopaedic and Trauma Surgery,2013,133(8):1129-1141.
[3] LINS M,STEFFENS C C,BASTIAN A,et al. Association between patient history and physical examination and osteoarthritis after ankle sprain[J]. International Journal of Sports Medicine,2017,38(9):717-724.
[4] 徐琼,来栓栓,杨梅,等理筋手法联合五味双柏膏治疗急性踝关节扭伤的临床报道[J].中国中医骨伤科杂志,2018,26(9):73-74.
[5] 李永恒,洪茂,张岩峰,等.中医骨伤科对踝关节扭伤的认识及治疗方法[J].中国中医骨伤科杂志,2017,25(3):70-71.
[6] 胥少汀.实用骨科学[M].4版.北京:人民军医出版社,2012:1059-1062.
[7] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:64-65.
[8] SIMON R R,SHERMEN S C,KOENIGSKNECHT S J.急诊骨科学—四肢骨折和损伤的急救处置[M]. 戴国锋,译.5版.北京:人民军医出版社,2012:327.
[9] 於滔,丰伟,刘意.马钱子巴布剂体外透皮实验及促透剂的筛选[J].中国医院药学杂志,2018,38(3):229-233.
[10] VISHWANATHAN K,BRAITHWAITE I. Comparative responsiveness of four visual analogue scales in microdiscectomy for lumbar disc herniation[J]. European Journal of Orthopaedic Surgery & Traumatology,2019,29(6):1199-1204.
[11] NELSON F S,MICHAEL S,LAMAR L F.Evaluation of the validity of the AOFAS clinical rating systems by correlation to the SF-36[J].Foot & Ankle International,2003,24(1):50-55.
[12] 邬昌求,陈敏.巨刺疗法配合推拿治疗急性踝关节扭伤的临床观察[J].针灸临床杂志,2017,33(2):25-27.
[13] 李应志,张吉,邵长丽,等.冰敷与热敷分别联合推拿对家兔急性骨骼肌损伤修复作用的比较[J].广州中医药大学学报,2019,36(8):1188-1194.
[14] 高景华.筋伤疾病诊疗经验[M].北京:中国中医药出版社,2014:55-56.
[15] VUURBERG G,HOORNTJE A,WINK L M,et al. Diagnosis,treatment and prevention of ankle sprains:update of an evidence-based clinical guideline[J]. British Journal of Sports Medicine,2018,52(15):956-970.
[16] 姜仁建,蒲萍,曹洪辉,等.中医理筋手法加中药外敷对急性踝关节扭伤患者静脉血SOD及MDA水平的影响[J].中国中医急症,2019,28(8):1408-1410.
[17] 龚志兵,庄至坤,张焕堂,等.骨散外敷治疗急性踝关节扭伤气滞血瘀证的临床研究[J].中医正骨,2018,30(12):13-17.
[18] 余翔,金志超,梁德,等.急性踝关节扭伤的中医药治疗进展[J].中国中医急症,2017,26(12):2169-2172.
[19] 张岁玲,史亚军,汤丽芝,等.骨伤科外用传统中药剂型的应用探析[J].陕西中医,2017,38(6):789-790.
[20] 吴师机.理瀹骈文[M].北京:中国中医药出版社,2007:14.
[21] 陈军,李钰,苏曼.中药经皮给药脂质体的研究与展望[J].南京中医药大学学报,2019,35(5):623-630.
[22] 周楠,曹欢,笔雪艳,等.中药传统剂型:黑膏药的研究进展[J].中国药品标准,2018,19(6):433-436.
[23] 王丹丹,李无阴.黑膏药制剂工艺存在的问题及改良研究的现状[J].中国医药导报,2019,16(4):30-33.
[24] 徐蕴杰,张云亮,李鞠,等.自拟舒筋活血方熬制黑膏药贴敷治疗气滞血瘀型腰椎间盘突出症的临床研究[J].中国医药导报,2019,16(1):130-133.

备注/Memo

备注/Memo:
(收稿日期:2019-12-11) 基金项目:中国中医科学院望京医院院级课题(WJYY2018-03) △通信作者 E-mail:20160935128@bucm.edu.cn
更新日期/Last Update: 2020-08-10