参考文献/References:
[1] 赵德伟.成人股骨头坏死临床诊疗指南(2016)[J].中华骨科杂志,2016,36(15):945-954.
[2] 王子华,赵德伟.基于显微灌注和三维数字成像的股骨头血供解剖学研究为青壮年股骨颈骨折治疗策略带来的新启示[J].中华显微外科杂志,2017,40(5):417-418.
[3] 徐西林,胡海,张晓峰,等.活骨注射液治疗股骨头坏死的扫描电镜观察[J].中国中医骨伤科杂志,2017,25(2):1-5.
[4] 曾平,陈金龙,李金溢,等.创伤性股骨头坏死血清差异蛋白质组学的研究[J].中国矫形外科杂志,2019,27(5):453-458.
[5] 张颖,张蕾蕾,柴玉娜,等.创伤性股骨头坏死中差异miRNA的筛选与验证[J].中华创伤骨科杂志,2017,19(11):978-985.
[6] 巫娟,张峰,郭莉.浅析不同原因所致缺血性坏死股骨头的病理改变及bFGF的表达[J].当代医药论丛,2018,16(21):65-67.
[7] SUN Z,CAO X,ZEBING L,et al.MiR-103 inhibits osteoblast proliferation mainly through suppressing Cav1.2 expression in simulated microgravity[J].Bone,2015,76:121-128.
[8] ZHOU G,ZHANG Y,ZENG L,et al.Should thorough debridement be used in fibular allograft with impaction bone grafting to treat femoral head necrosis:a biomechanical evaluation[J].BMC Musculoskeletal Disorders,2015,16(1):140.
[9] HU Z,WANG Y,SUN Z,et al.miRNA-132-3p inhibits osteoblast differentiation by targeting Ep300 in simulated microgravity[J].Scientific Reports,2015,5(2):18655.
[10] WU X,ZHANG Y,GUO X,et al.Identification of differentially expressed microRNAs involved in non-traumatic osteonecrosis through microRNA expression profiling[J].Gene,2015,565(1):22-29.
[11] 杨玉宝,刘洪亚,阚金庆,等.股骨头坏死患者坏死骨组织中miRNA 表达谱变化[J].山东医药,2015,55(34):74-75.
[12] OSKOWITZA Z,LU J,PENFORNIS P,et al.Human multipotent stromal cells from bone marrow and micro RNA:regulation of differentiation and leukemia inhibitory factor expression[J].Proceedings of the National Academy of Sciences of the United States of America,2008,105(47):18372-18377.
[13] 朱超,姜彦峰.股骨头坏死患者血清miRNA-210,miRNA-23检测的应用价值[J].现代检验医学杂志,2017,32(4):57-59.
[14] 彭俊,刘英杰,宗阳,等.miRNA-125b调控Runx2/Osx表达对骨髓间充质干细胞成骨机制的影响[J].东南国防医药,2019,21(2):124-129.
[15] 张颖,张蕾蕾,孙瑞波,等.补肾活血法对人骨髓间充质干细胞成骨能力的影响及miR-93-5p对其的抑制作用[J].中华中医药杂志,2018,33(2):667-671.
[16] ZENG Y,QU X,LI H,et al.MicroRNA-100 regulates osteogenic differentiation of human adipose-derived mesenchymal stem cells by targeting BMPR2[J].FEBS Letters,2012,586(16):2375-2381.
[17] ZHANG Y,XIE R L,GORDON J,et al.Control of mesenchymal lineage progression by MicroRNAs targeting skeletal gene regulators Trps1 and Runx2[J].Journal of Biological Chemistry,2012,287(3):21926-21935.
[18] LI Z,HASSAN M Q,VOLINIA S,et al.A microRNA signature for a BMP2-induced osteoblast lineage commitment program[J].PNAS,2008,105(1):13906-13911.
[19] 丁永利,陈星,赵明明,等.miR-133a对骨形态发生蛋白2诱导的鼠前成骨细胞分化的影响及其作用机制[J].中医正骨,2014,26(7):3-7.
[20] LIU H,SUN Q,WAN C,et al.MicroRNA-338-3p regulates osteogenic differentiation of mouse bone marrow stromal stem cells by targeting Runx2 and Fgfr2[J].Journal of Cellular Physiology,2014,229(10):1494-1502.
[21] 王运佳,张宏其,余洪贵,等.MicroRNA-30a通过Sox9调控骨髓间充质干细胞软骨分化的研究[J].中国矫形外科杂志,2018,26(20):69-74.
[22] BHUSHAN R,GRUNHAGE N,JOHANNE S,et al.miR-181a promotes osteoblastic differentiation through repression of TGF-β signaling molecules[J].The International Journal of Biochemistry & Cell Biology,2013,45(3):696-705.
[23] MIZUNO Y,TOKUZAWA Y,NINOMIYA Y,et al.miR-210 promotes osteoblastic differentiation through inhibition of AcvR1b[J].FEBS Letters,2009,583(1):2263-2268.
[24] JIA J,FENG X,XU W,et al.MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis[J].Experimental & Molecular Medicine,2014,46(46):e107.
[25] LIU Y,LIU G,ZHANG H,et al.MiRNA-199a-5p influences pulmonary artery hypertension via downregulating Smad3[J].Biochemical and Biophysical Research Communications,2016,473(4):859-866.
[27] LI Z,HASSAN M Q,VOLINIA S,et al.A microRNA signature for a BMP2-induced osteoblast lineage commitment program[J].Proceedings of the National Academy of Sciences of the United States of America,2008,105(37):13906-13911.
[28] SHI L,FENG L,LIU Y,et al.MicroRNA-218 promotes osteogenic differentiation of mesenchymal stem cells and accelerates bone fracture healing[J].Calcified Tissue International,2018,103(3):1-10.
[29] 孙璇,魏泽全,布文奂,等.聚乙烯亚胺递送miR-218及miR-26a对骨髓间充质干细胞成骨分化的影响[J].中国组织工程研究,2017,21(25):3964-3970.
[30] SU X,LIAO L,SHUAI Y,et al.MiR-26a functions oppositely in osteogenic differentiation of BMSCs and ADSCs depending on distinct activation and roles of Wnt and BMP signaling pathway[J].Cell Death and Disease,2015,6(8):e1851.
[31] EHLINGER M,MOSER T,ADAM P,et al.Early prediction of femoral head avascular necrosis following neck fracture[J].Orthop Traumatol Surg Res,2011,97(1):79-88.
[32] FENG Y,YANG S H,XIAO B J,et al.Decreased in the number and function of circulation endothelial progenitor cells in patients with avascular necrosis of the femoral head.[J].Bone,2010,46(1):32-40.
[33] ESOUZA C V,HAMEL F G,BIDASEE K,et al.Role of inflammation and insulin resistance in endothelial progenitor cell dysfunction[J].Diabetes,2011,60(4):1286-1294.
[34] SHU M,JIATIAN C,LIANSHENG W,et al.MicroRNA 107 partly inhibits endothelial progenitor cells differentiation via HIF-1β[J].PLoS One,2012,7(7):e40323.
[35] CHENG BB,QU MJ,WU LL,et al.MicroRNA-34a targets forkhead box j2 to modulate differentiation of endothelial progenitor cells in response to shear stress[J].Journal of Molecular and Cellular Cardiology,2014,74(1):4-12.
[36] ZHANG J,ZHANG Z,ZHANG D Y,et al.MicroRNA 126 inhibits the transition of endothelial progenitor cells to mesenchymal cells via the PIK3R2-PI3K/Akt signalling pathway[J].PLoS One,2013,8(12):e83294.
[37] UMEZU T,TADOKORO H,AZUMA K,et al.Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1[J].Blood,2014,124(25):3748.
[38] LI D,YANG P Y,XIONG Q H,et al.MicroRNA-125a/b-5p inhibits endothelin-1 expression in vascular endothelial cells[J].Journal of Hypertension,2010,28(8):1646-1654.
[39] PEKARSKY Y,BALATTI V,CROCE C M.BCL2 and miR-15/16:from gene discovery to treatment[J].Cell Death & Differentiation,2017,25(1):25-26.
[40] LEE S,JUNG Y,CHOI Y,et al.Targeting of Runx3 by miR-130a and miR-495 cooperatively increases cell proliferation and tumor angiogenesis in gastric cancer cells[J].Oncotarget,2015,6(32):33269-33278.
[41] 宿云娟,孙玉聪,楚海荣,等.miR-92a对大鼠骨髓源性内皮祖细胞功能的影响[J].中国细胞生物学学报,2016,38(6):676-681.
[42] 潘群文,刘雅静,何彩霞,等.miR-155对缺血性脑卒中小鼠内皮祖细胞功能的调节作用[J].广东医学院学报,2015,33(4):385-388.
[43] COWAN C,MURALEEDHARAN C K,ODNNELL J J,et al.MicroRNA-146 inhibits thrombin-induced NF-κB activation and subsequent inflammatory responses in human retinal endothelial CellsmiR-146 is a negative regulator of NF-κB[J].Invest Ophthalmol Vis Sci,2014,55(8):4944-4951.
[44] 余华.骨髓间充质干细胞miRNA-196a异常表达与激素性股骨头坏死关联的临床研究[J].安徽医药,2018,22(1):68-71.
[45] YU D,GEREEN B,MARRONE A,et al.Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma[J].Sci Rep,2015,5(5):8534.