[1]刘广亚 许育兵△ 张喻 陈旭琼 朱展鸿 单桂秋.富血小板血浆与血小板裂解液治疗跟腱炎的比较研究[J].中国中医骨伤科杂志,2019,27(10):22-25.
　LIU Guangya XU Yubing ZHANG Yu CHEN Xuqiong ZHU Zhanhong SHAN Guiqiu.Comparative Study on Treatment of Achilles Tendinitis by Platelet-rich Plasma and Platelet Lysate[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2019,27(10):22-25.
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富血小板血浆与血小板裂解液治疗跟腱炎的比较研究()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第27卷
期数:
2019年10期
页码:
22-25
栏目:
临床研究
出版日期:
2019-10-10

文章信息/Info

Title:
Comparative Study on Treatment of Achilles Tendinitis by Platelet-rich Plasma and Platelet Lysate
文章编号:
1005-0205(2019)10-0022-04
作者:
刘广亚1 许育兵1△ 张喻1 陈旭琼2 朱展鸿1 单桂秋1
1南部战区总医院输血科(广州,510010) 2南部战区总医院骨科
Author(s):
LIU Guangya1 XU Yubing1 ZHANG Yu1 CHEN Xuqiong2 ZHU Zhanhong1 SHAN Guiqiu1△
1Department of Blood Trafusion,General Hospital of Southern Theater Command,Guangzhou 510010,China; 2Department of Orthopaedics,General Hospital of Southern Theater Command,Guangzhou 510010,China.
关键词:
跟腱炎;  富血小板血浆;  血小板裂解液;  临床疗效
Keywords:
achilles tendinitis;  platelet rich plasma;  platelet lysate;  clinical efficacy
分类号:
R686.1
文献标志码:
A
摘要:
目的:观察富血小板血浆与血小板裂解液治疗跟腱炎的有效性与安全性。方法:40例跟腱炎患者分为A和B两组,每组20例。A组对病患部位注射富血小板血浆,B组注射改良方法制备的血小板裂解液。分别评估A,B两组治疗前及治疗后1,3及6个月的美国矫形外科足踝协会(AOFAS)和疼痛视觉模拟评分量表(VAS)指标数据以及超声改变结果。结果:两组患者与治疗前比较,治疗后的AOFAS评分显著增加,差异有统计学意义(P<0.01),VAS评分结果显著降低,差异有统计学意义(P<0.01); 两组间差异无统计学意义(P>0.05)。超声影像学显示:A组75%的患者跟腱病变部位有所改善,B组80%的患者有上述改变。结论:血小板裂解液在治疗跟腱炎中显示与富血小板血浆同样的临床疗效,使用改良的血小板裂解液比富血小板血浆具有更好的应用前景。
Abstract:
Objective:To observe the clinical effect of treatment of Achilles tendinitis with platelet-rich plasma(PRP)and platelet lysate(PL).Methods:Forty patients with Achilles tendinitis were randomly divided into treatment group and control group.There were 20 cases in each group.We injected platelet-rich plasma into the patient of group A,and injected the platelet lysate prepared by the improved method to group B.We recorded before treatment and 1,3 and 6 months after treatment in group A and B respectively about the changes of American orthopaedic foot & ankle society(AOFAS)and visual analogue scale(VAS)pain scale index data and ultrasound.Results:Group A and B were compared before and after treatment:at 1 month,3 months,and 6 months after treatment,AOFAS scores increased significantly(P<0.01),VAS scores decreased significantly(P<0.01),there was no significant difference between the two groups(P>0.05).Ultrasound imaging showed:in group A,75% of the patients had different degrees of changes.In group B,80% of the patients had the above changes.Conclusion:Platelet lysate has the same clinical effect as platelet-rich plasma in the treatment of Achilles tendinitis.The use of improved PL has a better application prospect than PRP.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:后勤科研面上项目(CLB18JO38) 广东省医学科学技术研究基金(A2018221)△通信作者 E-mail:645608069@qq.com
更新日期/Last Update: 2019-10-10