[1]唐永明 王志英.关节内注射低浓度臭氧联合玻璃酸钠治疗膝骨关节炎49例[J].中国中医骨伤科杂志,2019,27(03):66-68.
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关节内注射低浓度臭氧联合玻璃酸钠治疗膝骨关节炎49例()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第27卷
期数:
2019年03期
页码:
66-68
栏目:
临床报道
出版日期:
2019-02-28

文章信息/Info

文章编号:
1005-0205(2019)03-0066-03
作者:
唐永明1 王志英1
1西宁市第三人民医院疼痛康复科(西宁,810005)
关键词:
臭氧 玻璃酸钠 膝骨关节炎 疗效 安全性
分类号:
R684.3
文献标志码:
B
摘要:
目的:探讨关节内注射低浓度臭氧联合玻璃酸钠对膝骨关节炎(KOA)患者白介素6(IL-6)、C反应蛋白(CRP)、E-钙粘附蛋白(E-cad)的影响。方法:选取2016年1月至2018年1月本院KOA患者49例,所有患者给予膝关节内注射低浓度(20 mg/L)臭氧联合玻璃酸钠治疗。结果:KOA患者治疗后IL-6,hs-CRP及E-cad明显低于治疗前,患者治疗7 d,1个月及3个月后疼痛视觉模拟评分法(VAS)得分明显低于治疗前,差异有统计学意义(P<0.05)。KOA患者膝功能优29例,良18例,中2例,差0例,优良率为95.92%; 患者发生关节酸软感5例,肿胀3例,发热3例,感染0例,并发症发生率为22.45%.结论:膝关节内注射低浓度臭氧联合玻璃酸钠可有效改善KOA患者IL-6,hs-CRP及E-cad,有利于改善患者膝功能及疼痛,且安全性好,值得临床推广。

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更新日期/Last Update: 2019-02-28