[1]朱晓龙,邹德宝,鞠昌军,等.富血小板血浆联合头颈开窗髂骨植骨治疗股骨头坏死的临床研究[J].中国中医骨伤科杂志,2018,26(10):36.
　ZHU Xiaolong,ZOU Debao,JU Changjun,et al.Clinical Observation of Platelet Rich Plasma Combined with Opening Bone Grafting in Head and Neck in the Treatment of Osteonecrosis of the Femoral Head[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2018,26(10):36.
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富血小板血浆联合头颈开窗髂骨植骨治疗股骨头坏死的临床研究()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第26卷
期数:
2018年10期
页码:
36
栏目:
临床研究
出版日期:
2018-10-10

文章信息/Info

Title:
Clinical Observation of Platelet Rich Plasma Combined with Opening Bone Grafting in Head and Neck in the Treatment of Osteonecrosis of the Femoral Head
文章编号:
1005-0205(2018)10-0036-04
作者:
朱晓龙1; 邹德宝2; 鞠昌军2; 严伟2; 李磊2; 余昕2; 张亚霖2; 金鑫2; 姜红江1; 2△
1安徽中医药大学(合肥,230000) 2山东省文登整骨医院
Author(s):
ZHU Xiaolong1; ZOU Debao2; JU Changjun2; YAN Wei2; LI Lei2; YU Xin2; ZHANG Yalin2; JIN Xin2; JIANG Hongjiang1; 2△
1Anhui University of Traditional Chinese Medicine,Hefei 230000,Shandong China; 2Shandong Wendeng Orthopedics Hospital,Wendeng 264400,Shandong China.
关键词:
股骨头坏死;  富血小板血浆;  治疗
Keywords:
femur head necrosis;  platelet-rich plasma;  therapeutics
分类号:
R681.8
文献标志码:
A
摘要:
目的:探讨富血小板血浆(PRP)联合头颈开窗髂骨植骨治疗股骨头坏死的临床疗效。方法:2015年9月至2017年2月,采取前瞻临床随机对照研究,对44例ARCOⅡ-Ⅲ期股骨头坏死患者进行研究。其中观察组22例,采用经股骨头颈部开窗髂骨植骨术,配合术后髋关节PRP注射治疗。对照组22例,仅给予经股骨头颈部开窗髂骨植骨术。记录两组患者术前VAS评分和Harris评分。术后定期随访,记录两组患者术后1年VAS评分和Harris评分,并根据术后1年影像学进展情况计算改善率。结果:所有44例髋术后均未发生感染、神经血管损伤等术后并发症,所有病例均获得随访。两组患者术后1年的VAS评分和Harris评分与术前比较,差异有统计学意义(P<0.05)。术后1年VAS评分,两组间比较差异无统计学意义(P>0.05)。术后1年Harris评分,观察组优于对照组,差异有统计学意义(P<0.05)。术后1年,观察组股骨头坏死改善率90.90%高于对照组的63.64%.结论:富血小板血浆联合头颈开窗髂骨植骨治疗股骨头坏死疗效确切,髋关节功能改善明显,是一种较好的保髋治疗手段。
Abstract:
Objective:To evaluate the clinical effects of opening bone grafting in head and neck combined with platelet-rich plasma for treating osteonecrosis of femoral head.Methods:From September 2015 to February 2017,44 patients with stage Ⅱ-Ⅲ(ARCO)osteonecrosis of femoral head were studied.Twenty-two cases were in the observation group and 22 cases were in the control group.The observation group adopted opening bone grafting in head and neck combined with platelet-rich plasma,while the control group adopted opening bone grafting in head and neck.The two groups were compared before and after the surgery by Harris scores,VAS scores and imaging changes.Results:There were no complications of dislocation,periprosthetic fracture and infection within 12 months after surgery.Compared to the data before the treatment,VAS scores and Harris scores at one-year follow-up in both groups showed better outcomes(P<0.05).The VAS scores of the observation group was lower than that of the control group,but there was no significant difference between them(P>0.05).Harris score was better than the control group,with statistically significant difference(P<0.05).The rate of necrosis of femoral head in the observation group was 90.90%,which was higher than 63.64% in the control group(P<0.05).Conclusion:The effect of opening bone grafting in head and neck combined with platelet-rich plasma in the treatment of osteonecrosis of femoral head is accurate,and the improvement of hip function is obvious,which is a better means of hip treatment.

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备注/Memo

备注/Memo:
△通信作者 E-mail:boneman@163.com
更新日期/Last Update: 2018-10-10