参考文献/References:
[1] Silberberg R, Aufdermaur M, Adler JH.Degeneration of the intervertedral disks and spondylosis in aging sand rats[J].Archives of Pathology and Laboratory Medicine, 1979,103(5):231-235.
[2] Alini M,Eisenstein SM,ItoK,et al.Are animal models useful for studying human disc disorders/degeneration[J]? European Spine Journal,2008,17(1):2-19.
[3] Hunter CJ,Matyas JR,Duncan NA.Cytomorphology of notochordal and chondrocytic cells from the nucleus pulposus:a species comparison[J].Anat,2004,205:357-362.
[4] O'Connell GD,Vresilovic EJ,ElliottDM.Comparision of animals used in disc research to human lumbar disc geometry[J].Spine,2007,32(3):328-333.
[5] Showalter BL,Beckstein JC,Martin JT,et al.Comparision of animal discs used in disc research to human lumbar disc:torsion mechanics and collagen content[J].Spine(Phila Pa 1976),2012,37(15):E900-907.
[6] Clouet J,Pot-Vaucel M,Grimandi G,et al.Characterization of the age-dependent intervertedral disc changes in rabbit by correlation between MRI.histology and gene expression[J].BMC Musculoskelet Disord,2011,4(12):147-156.
[7] Lindblom K.Intervertedral-disc degeneration considered as a pressure atrophy[J].The Journal of Bone and Joint Surgery,1957,39(4):933-945.
[8] Court C,Colliou OK,Chin JR,et al.The effect of static in vivo bending on the murine intervertedral disc[J].Spine Journal,2001,1(4):239-245.
[9] Iatridis JC,Mente PL,Stokes IA, et al.Compression-induced changes in intervertedral disc properties in a rat tail model[J].Spine(Phila Pa 1976),1999,24(10):996-1002.
[10] Ching CT,Chow DH,Holmes AD,et al.The effect of cyclic compression on the mechanical properties of the intervertedral disc:an in vivo study in a rat tail model[J].Clinical Biomechanics,2003,18(3):182-189.
[11] Miyamoto S,Yonenobu K,Ono K.Experimental cervical spondylosis in the mouse[J].Spine(Phila Pa 1976),1991,16:S495-S500.
[12] Phillips FM,Reuben J, Wetzel FT.Intervertedral disc degeneration adjacent to a lumbar fusion[J].Journal of Bone and Joint Surgery B,2002,84(2):289-294.
[13] 桂柯科,尹望平,周飚,等.纤维环穿刺法建立兔椎间盘退变模型[J].中国矫形外科杂志,2010,18(21):1814-1816.
[14] Kim KS, Yoom ST, Li J, et al.Disc degeneration in the rabbit:a biochemical and radiological comparision between four disc injury models[J].Spine(Phila Pa 1976), 2005,30(1):33-37.
[15] Li D, Yang H, Huang Y,et al.Lumbar intervertedral disc puncture under C-arm fluoroscopy:a new rat model of lumbar intervertedral disc degeneration[J].Exp Anim, 2014,63(2):227-234.
[16] Zhou RP, Zhang ZM, Wang L, et al.Establishing a disc degeneration model using computed tomography-guided percutaneous puncture technique in the rabbit[J].Sury Res,2013,181(2):e65-74.
[17] Issy AC, Castania V, Castania M, et al.Experimental model of intervertedral disc degeneration by needle puncture in Wistar rats[J].Braz J Med Biol Res,2013,46(3):235-244.
[18] Zhang W, Li T, Gong Q, et al.A comparative study on establishing rabbit intervertedral disc degeneration models by three methods[J].Zhong guo Xiu Fu Chong Jian Wai Ke Za Zhi,2010,24(1):41-45.
[19] Boxberger JI, Auerbach JD, Sen S, et al.An in vivo model of reduced nucleus pulposus glycosaminoglycan content in the rat lumbar intervertedral disc[J].Spine(Phila Pa 1976),2008,33(2):146-154.
[20] Ruel N, Markova DZ, Adams SL, et al.Fibronectin fragments and the cleaving enzyme ADAM-8 in the degenerative human intervertedral disc[J].Spine(Phila Pa 1976),2014,39(16):1274-279.
[21] Liu HF, Zhang H, Qiao GX, et al.A novel rabbit disc degeneration model induced by fibronectin fragment[J].Joint Bone Spine,2013,80(3):301-306
[22] Oehme D, Goldschlager T, Ghosh P, et al.Cell-based therapies used to treat lumbar degenerative disc disease:a systematic review of animal studies and human clinical trials[J].Stem Cells International,2015,2015(2):946031-946016.
[23] Jeong JH, Jin ES, Min JK, et al.Human mesenchymal stem cells implantation into the degenerated coccygeal disc of the rat[J].Cytotechnology,2009,59(1):55-64.
[24] Sakai D, Mochida J, Iwashina T, et al.Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model:ptential and limitations for stem cell therapy in disc regeneration[J].Spine(Phila Pa 1976),2005,30(21):2379-2387.
[25] Hohaus C, Ganey TM, Minkus Y, et al.Cell transplantation in lumbar spine disc degeneration disease[J].European Spine Journal,2008,17(4):492-503.
[26] 沈祥,徐宏光,马明明,等.脂肪间充质干细胞注入退变椎间盘局部的作用[J].中国组织工程研究,2017,21(1):77-81.
[27] Oehme D, Ghosh P, Shimmon S, et al.Mesenchymal progenitor cells combined with pentosan poiysulfate mediating diac regeneration at the time of microdiscectomy:a preliminary study in an ovine model[J].Journal of Neurosurgery Spine,2014,20(6):657-669.
[28] Meisel HJ, Siodla V, Ganey T, et al.Clinical experience in cell-based therapeutics:disc chondrocyte transplantation:a treatment for degenerated or damaged intervertedral disc[J].Biomolecular Engineering,2007,24(1):5-21.
[29] Orozco L, Soler R, Morera C, etal.Intervertedral disc repair by autologous mesenchymal bone marrow cells:a pilot study[J].Transplantation, 2011,92(7):822-828.
[30] Bae HW, Amirdelfan K, Coric D, et al.A phase II study demonstrating efficay and safety of mesenchymal precursor cells in low back pain due to disc degeneration[J].The Spine Journal,2014,14(11):S31-S32.
[31] Pang X, Yang H, Peng B.Human umbilical cord mesenchymal stem cell transplantation for the treatment of chronicdiscogenic low back pain[J].Pain Physician,2014,17(4):E525-E530.
[32] Pettine KA, Murphy MB, Suzuki RK, et al.Percutaneous injection of autologous bone marrow concentrate cells significantly reduces lumbar discogenic pain through 12 months[J].Stem Cells,2015, 33(1):146-156.
[33] Elabd C, Centeno CJ, Schultz JR, et al.Intra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain:a long-term safety and feasibility study[J].J TranslMed,2016,14:253.
[34] Ding DC, Chang YH, Shyu WC, et al.Human umbilical cord mesenchymal stem cells:a new era for stem cell therapy[J].Cell Transplant,2015,24(3):339-347.
[35] Kumar H, Ha DH, Lee EJ, et al.Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain:1-year follow-up of aphase I study[J].Stem Cell Res Ther,2017,8(1):262.
[36] Millecamps M, Czerminski JT, Mathieu AP, et al.Behavioral signs of axial low back pain and motor impairment correlate with the severity of intervertedral disc degeneration in a mouse model[J].The Spine Journal,2015,15(12):2524-2537.
[37] Lai A, Moon A, Purmessur D, et al.Assessment of functional and behavioral changes sensitive to painful disc degeneration[J].Journal of Orthopaedic Research, 2015,33(5):755-764
[38] Olmarker K.Puncture of a lumbar intervertedral disc induces changes in spontaneous pain behavior:an experimental study in rats[J].Spine(Phila Pa 1976),2008,33(8):850-855.