[1]赫军 诸葛天谕 李冬冬 方苏亭△ 何宾 郑永昌 禹建春.独活寄生汤为主的中医综合疗法治疗强直性脊柱炎(脊痹寒湿犯腰证)的临床观察[J].中国中医骨伤科杂志,2017,25(02):19-23.
　HE Jun ZHUGE Tianyu LI Dongdong FANG Suting HE Bin ZHENG Yongchang YU Jianchun.Comprehensive Therapy of Ankylosing Spondylitis(Cold Dampness Syndrome)with Traditional Chinese Medicine Based on Duhuojisheng Decoction[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2017,25(02):19-23.
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独活寄生汤为主的中医综合疗法治疗强直性脊柱炎(脊痹寒湿犯腰证)的临床观察()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第25卷
期数:
2017年02期
页码:
19-23
栏目:
临床研究
出版日期:
2017-02-15

文章信息/Info

Title:
Comprehensive Therapy of Ankylosing Spondylitis(Cold Dampness Syndrome)with Traditional Chinese Medicine Based on Duhuojisheng Decoction
文章编号:
1005-0205(2017)02-0019-05
作者:
赫军1 诸葛天谕1 李冬冬1 方苏亭1△ 何宾1 郑永昌1 禹建春1
1浙江台州市博爱医院(浙江 台州, 318050) △通信作者 E-mail:fst2012@sina.com
Author(s):
HE Jun1 ZHUGE Tianyu1 LI Dongdong1 FANG Suting1△ HE Bin1 ZHENG Yongchang1 YU Jianchun1
1Taizhou Boai Hospital, Taizhou 318050,Zhejiang China.
关键词:
强直性脊柱炎;  脊痹;  寒湿犯腰证;  腱端炎;  独活寄生汤;  中药熏蒸;  埋针;  练功;  中医综合疗法
Keywords:
ankylosing spondylitis;  spine arthralgia;  lumbar cold dampness syndrome;  enthesitis;  duhuojisheng decoction;  TCM fumigation;  needle-embedding;  exercise;  TCM comprehensive therapy
分类号:
R681.5
文献标志码:
A
摘要:
目的:观察经方独活寄生汤为主的中医综合疗法治疗强直性脊柱炎(脊痹寒湿犯腰证)的有效性和安全性。方法:选取强直性脊柱炎(脊痹寒湿犯腰证)患者70例,采用简单随机法分组方法分为两组:观察组给予独活寄生汤,配合中药熏蒸,腱端炎痛点埋针及练功等治疗; 对照组给予口服柳氮磺胺吡啶片及美乐昔康片治疗; 疗程90 d.采用中医证候积分、国际脊柱关节病协会(ASAS)制定的疗效评价因子以及不良事件等评价临床疗效及安全性。结果:两组患者治疗前的一般资料、中医证候积分、ASAS疗效评价因子等指标比较差异无统计学意义,具有可比性。各组患者治疗前后比较,各项指标有改善,差异有统计学意义(P<0.05)。组间比较,观察组在中医证候积分、患者疾病总体评价指数、晨僵等方面的改善优于对照组,差异有统计学意义(P<0.05)。两组患者均无严重不良事件发生。结论:经方独活寄生汤为主的中医综合疗法治疗强直性脊柱炎安全、有效,中医证候疗效优于常规西药。
Abstract:
Objective:To evaluate the safety and effect of TCM comprehensive therapy based on Duhuojisheng decoction in the treatment of ankylosing spondylitis(cold dampness syndrome). Methods:70 cases of ankylosing spondylitis were randomly divided into the observation group(treated with Duhuojisheng decoction combined with traditional Chinese medicine fumigation, needle-embedding and exercise for 90 days)and control group(treated with oral sulfasalazine tablets, Miller piroxicam tablets for 90 d).TCM syndrome scores, evaluation factors and adverse events made by ASAS Clinical were used to evaluate the efficacy and safety. Results:There was no significant difference between the two groups in general data, TCM syndrome scores, ASAS efficacy evaluation factors before treatment. After treatment, each index in two groups improved, with statistical significance(P<0.05).The TCM syndrome score, disease general evaluation index and stiffness in the observation group were better than those in the control group, with statistical significance(P<0.05). No serious adverse events occurred in the two groups. Conclusion:TCM comprehensive therapy based on Duhuojisheng decoction is safe and effective in the treatment of ankylosing spondylitis. TCM syndrome therapy is better than conventional Western medicine.

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备注/Memo

备注/Memo:
基金项目:台州市科技计划项目(1401KY35)
更新日期/Last Update: 2017-09-08