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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:

第24卷

期数:

2016年03期

页码:

18-20

栏目:

临床研究

出版日期:

2016-03-03

文章信息/Info

Title:

Analysis of Influencing Factors of the Efficacy of TCM Hip-preserving Treatment in Early-to-middle Stage of Non-traumatic Osteonecrosis of the Femoral Head

文章编号:

1005-0205(2016)03-0018-03

作者:

刘波¹ 林坤弟² 何海军² 沈丹青¹ 王振涛¹ 陈卫衡^2△

1.贵阳中医学院(贵阳,550002)
2.中国中医科学院望京医院
△.通信作者 E-mail:drchenweiheng@163.com

Author(s):

LIU Bo¹ LIN Kundi² HE Haijun² SHEN Danqing¹ WANG Zhentao¹ CHEN Weiheng^2△

1.Guiyang College of Traditional Chinese Medicine,Guiyang 550002,China;
2.Wangjing Hospital of China Academy of Chinese Medical Sciences,Beijing 100102,China.

关键词:

非创伤性;  股骨头坏死;  中医药保髋;  疗效影响因素

Keywords:

non-traumatic;  osteonecrosis of the femoral head;  TCM hip-preserving;  influencing factors of the efficacy

分类号:

R681.8

文献标志码:

A

摘要:

目的:总结并分析影响早中期非创伤性股骨头坏死(ONFH)中医药保髋治疗的疗效影响相关因素,为提高临床效果提供理论依据。方法:选取经中国中医科学院望京医院骨关节三科住院接受中医药保髋治疗,随访时间超过1年的早中期(ARCO Ⅱ-Ⅲa期)非创伤性ONFH,影像学检查结果为加重的患者30例,设为加重组; 随机选取同期在本科住院接受相同治疗方法,影像学检查结果稳定的早中期非创伤性ONFH患者30例,设为稳定组。通过Excel表格,采用双人双录,专人核对的方式,收集两组患者的临床病历资料,分析并比较两组患者在年龄、性别、职业、体重指数、病程、饮酒史、激素使用史、拄拐因素方面的差异性。结果:加重组与稳定组在年龄、体重指数、性别比率及末次随访Harris评分比较上,差异均无统计学意义(P>0.05); 加重组病程为(4.10±2.09)年,高于稳定组的(2.66±1.39)年,差异有统计学意义(P<0.05); 加重组体力劳动者为70%,与稳定组的43.3%相比,差异有统计学意义(P<0.05); 加重组酒精致病因素为43.3%,明显低于稳定组的70%(P<0.05); 加重组激素致病因素为56.7%,明显高于稳定组的30%(P<0.05)。结论:职业、病程、饮酒史、激素使用史、拄拐因素对早中期非创伤性股骨头坏死保髋治疗疗效影响明显,治疗中需加以重视。

Abstract:

Objective:To summarize and analyze related influencing factors of the efficacy of TCM hip-preserving treatment in early-to-middle stage of non-traumatic osteonecrosis of the femoral head(ONFH). Methods:Thirty inpatients of non-traumatic ONFH(ARCO stage Ⅱ-Ⅲa)with TCM hip-preserving treatment at the Third Department of Osteoarthropathy,Wangjing Hospital of China Academy of Chinese Medical Sciences,were assigned to the aggravated group,who were followed up more than one-year and diagnosed as aggravated by radiologic findings. Additional 30 inpatients of non-traumatic ONFH(ARCO stage II-IIIa)on the same treatment at the same hospital were assigned to the stable group,who were diagnosed as stabled by radiologic findings. The clinical data of medical records were collected from patients of two groups using double entry and validation with excel. The age,gender,occupation,body mass index(BMI),course,drinking history,steroid using history,and crutches using history were compared between the two groups. Results:Following TCM hip-preserving treatment,among influencing factors of the efficacy,there were no significant differences in age,BMI,male/female ratio,and Harris score at last followed-up between two groups(P>0.05). The course was longer in the aggravated group than in the stable group(4.10±2.09 vs. 2.66±1.39 years; P<0.05). There were 70% of patients were manual workers in the aggravated group compared with the stable group(43.3%)(P<0.05). For incidence of pathogenesis of alcohol,the aggravated group was markedly lower than the stable group(43.3% vs. 70%,P<0.05). For incidence of pathogenesis of steroid using,the aggravated group was markedly higher than the stable group(56.7% vs. 30%,P<0.05). Conclusion:Such factors as occupation,course,drinking history,steroid using history,and crutches using history have marked effects on hip-preserving treatment in early-to-middle stage of non-traumatic ONFH,and we should be pay attention in clinical treatment.

备注/Memo

备注/Memo:

基金项目:国家自然科学基金项目(81373656)

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更新日期/Last Update: 2016-03-15