[1]肖伟 彭力平 林栋栋.牛膝醇提物透入疗法对膝骨性关节炎的疗效观察[J].中国中医骨伤科杂志,2015,23(08):37-40.
　XIAO Wei PENG Liping LIN Dongdong.Effect of Achyranthes Bidentata Alcohol Extract on Knee Osteoarthritis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2015,23(08):37-40.
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牛膝醇提物透入疗法对膝骨性关节炎的疗效观察
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第23卷
期数:
2015年08期
页码:
37-40
栏目:
临床研究
出版日期:
2015-08-15

文章信息/Info

Title:
Effect of Achyranthes Bidentata Alcohol Extract on Knee Osteoarthritis
文章编号:
1005-0205(2015)08-0037-04
作者:
肖伟1 彭力平1 林栋栋2
1.广东省深圳市中医院(广东 深圳,518033)
2.广州中医药大学
Author(s):
XIAO Wei1 PENG Liping1 LIN Dongdong2
1.Shenzhen Hospital of Traditional Chinese Medicine, Shenzhen 518033,Guangdong China;
2.Guangzhou University of Traditional Chinese Medicine, Guangzhou 510006, China.
关键词:
牛膝醇提物;  透入;  膝骨性关节炎;  疗效观察
Keywords:
achyranthes alcohol extraction;  penetration;  knee osteoarthritis;  efficacy observation
分类号:
R684.3
文献标志码:
A
摘要:
目的:验证牛膝醇提物透入疗法对膝骨性关节炎的临床疗效。方法:采用随机对照研究方式,选择70 例单膝骨性关节炎患者,治疗组40 例采用牛膝醇提物透药入治疗,对照组30 例采用正清风痛宁注射液透入治疗,连续治疗3 周,观察、比较两组治疗前后波士顿利兹骨关节炎(BLOKS)评分、西安大略和麦克马斯特大学骨关节炎(WOMAC)评分及膝关节负重与非负重疼痛积分。结果:牛膝醇提物能有效降低患者BLOKS评分中滑膜炎、关节积液积分、WOMAC评分及膝关节负重、非负重痛积分,且与治疗前对比差异均有统计学意义(P<0.05); 两组治疗后行组间对比,在关节积液、滑膜炎及膝关节非负重痛积分上两者差异无统计学意义(P>0.05),而在WOMAC评分、膝关节负重痛积分上治疗组优于对照组,且差异有统计学意义(P<0.05)。结论:牛膝醇提物透入疗法可有效减轻膝骨性关节炎患者负重痛,降低WOMAC评分、BLOKS滑膜炎及关节积液积分,其中对WOMAC评分及膝关节负重痛积分的降低作用优于正清风痛宁组。
Abstract:
Objective:To verify the clinical efficacy of achyranthes alcohol extract in the treatment of knee osteoarthritis. Methods: 70 patients with knee osteoarthritis were selected according to randomized controlled study. The treatment group(40 cases )underwent achyranthes alcohol extract penetration therapy. The control group(30 cases)were treated with Zhengqingfengtongning injection penetration. The Boston Leeds Osteoarthritis(BLOKS)score, the Western Ontario and McMaster Universities Osteoarthritis(WOMAC)score, the knee weight-bearing and non-weight-bearing pain points were compared before and after the treatment in the two groups 3 weeks after the treatment. Results: Achyranthes alcohol extract can effectively reduce the BLOKS score, WOMAC score, knee weight-bearing and non-weight-bearing pain points. The difference was statistically significant compared with before and after treatment(P<0.05).The WOMAC score and knee weight-bearing pain points in the treatment group was better than that in the control group, and the difference was statistically significant(P<0.05).Conclusion:Achyranthes alcohol extract penetration therapy can effectively reduce knee weight-bearing pain in patients with osteoarthritis, decrease WOMAC score, BLOKS synovitis and joint effusion points. The reducing effect of WOMAC score and knee weight-bearing points were better than that of Zhengqingfengtongning group.

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备注/Memo

备注/Memo:
收稿日期:2015-02-02
更新日期/Last Update: 2015-08-15