[1]仇湘中,蒋盛昶,张信成,等.腰椎间盘突出症中医证型与血清 TNF-α水平相关性研究[J].中国中医骨伤科杂志,2015,23(06):39-41.
　QIU Xiangzhong,JIANG Shengchang,ZHANG Xincheng,et al.Correlation of TCM Syndrome and Serum TNF-α Levels in Patients with Lumbar Disc Herniation[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2015,23(06):39-41.
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腰椎间盘突出症中医证型与血清 TNF-α水平相关性研究
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第23卷
期数:
2015年06期
页码:
39-41
栏目:
临床研究
出版日期:
2015-06-15

文章信息/Info

Title:
Correlation of TCM Syndrome and Serum TNF-α Levels in Patients with Lumbar Disc Herniation
文章编号:
1005-0205(2015)06-0039-03
作者:
仇湘中1;  蒋盛昶1;  张信成1;  唐皓1;  夏爱民1△;  易振宇1;  张旭桥2
1.湖南省中医药研究院附属医院(长沙,410006)
2.湖南省湘潭市中医医院
△.通信作者 E-mail:2267811679@qq.com
Author(s):
QIU Xiangzhong1;  JIANG Shengchang1;  ZHANG Xincheng1;  TANG Hao1;  XIA Aimin1;  YI Zhenyu1;  ZHANG Xuqiao2
1. Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine,Changsha 410006,China
2. Xiangtan Hospital of Traditional Chinese Medicine
关键词:
腰椎间盘突出症;  中医证型;  血清TNF-α
Keywords:
lumbar disc herniation;  TCM syndrome;  serum TNF-α
分类号:
R681.5
文献标志码:
A
摘要:
目的:探讨血清肿瘤坏死因子-α(TNF-α)水平在腰椎间盘突出症中医证型的分布规律。方法:采用前瞻性研究方法收集120例腰椎间盘突出症患者,按瘀血证、肾虚证、寒湿证、湿热证分为4组,观察比较各组血清TNF-α水平。结果:1)证型分布:瘀血证42例(35%),肾虚证33例(27.5%),寒湿证30例(25%),湿热证15例(12.5%); 2)血清TNF-α水平按肾虚证组、寒湿证组、湿热证组、瘀血证组呈逐步增高趋势; 3)血清TNF-α水平在腰椎间盘突出症中医各证型比较:瘀血证组与肾虚证组、寒湿证组比较差异均有统计学意义(P<0.01),寒湿证组与湿热证组、瘀血证组比较差异均有统计学意义(P<0.01),湿热证组与肾虚证组、寒湿证组比较差异均有统计学意义(P<0.01),肾虚证组与湿热证组、瘀血证组比较差异均有统计学意义(P<0.01),而瘀血证组与湿热证组; 肾虚证组与寒湿证组比较差异无统计学意义(P>0.05)。结论:腰椎间盘突出症中医证型与血清TNF-α水平具有一定相关性,可用于辅助诊断中医证型。
Abstract:
Objective:To explore the distribution of serum levels of TNF-α in different TCM syndromes types of lumbar disc herniation.Methods:120 patients with LDH were divided into blood stasis syndrome,kidney deficiency syndrome,cold- dampness syndrome and damp-heat syndrome groups.The serum TNF-α levels in each group were observed and compared.Results:1)Syndrome distribution:blood stasis syndrome 42 cases(35%),kidney deficiency syndrome 33 cases(27.5%),cold-dampness syndrome 30 cases(25%),damp-heat syndrome 15 cases(12.5%).2)Serum levels of TNF-α showed a gradual increasing trend by kidney deficiency syndrome group,cold- dampness syndrome group,damp-heat syndrome group and blood stasis syndrome group.3)The difference of serum TNF-α level between blood stasis syndrome group and damp-heat syndrome group shows no statistically significant.And the difference of serum TNF-α level between kidney deficiency syndrome group and cold- dampness syndrome group shows no statistically significant too.The differences of serum TNF-α level among all the other groups were statistically significant(P<0.01).Conclusion:TCM syndrome and serum TNF-α levels have some relevance in patients with LDH,which is useful in the diagnosis of the TCM Syndrome.

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备注/Memo

备注/Memo:
收稿日期:2014-08-08
基金项目:湖南省卫生厅中医药科研基金项目(201134)
更新日期/Last Update: 2015-06-10