[1]张彦东 蔡同川 李显.消肿镇痛散外敷联合超短波治疗急性踝关节扭伤——基于距腓后韧带修复与足背动脉血流改善的机制探讨[J].中国中医骨伤科杂志,2026,34(05):51-57.[doi:10.20085/j.cnki.issn1005-0205.260508]
　ZHANG Yandong,CAI Tongchuan,LI Xian.Effects of External Application of Xiaozhong Zhentong Powder Combined with Ultra Short Wave Therapy on the Thickness of the Posterior Talofibular Ligament and the Dorsal Foot Artery Blood Flow in Patients with Acute Ankle Sprain[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2026,34(05):51-57.[doi:10.20085/j.cnki.issn1005-0205.260508]
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消肿镇痛散外敷联合超短波治疗急性踝关节扭伤——基于距腓后韧带修复与足背动脉血流改善的机制探讨()

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第34卷
期数:
2026年05期
页码:
51-57
栏目:
临床研究
出版日期:
2026-05-10

文章信息/Info

Title:
Effects of External Application of Xiaozhong Zhentong Powder Combined with Ultra Short Wave Therapy on the Thickness of the Posterior Talofibular Ligament and the Dorsal Foot Artery Blood Flow in Patients with Acute Ankle Sprain
文章编号:
1005-0205(2026)05-0051-07
作者:
张彦东 蔡同川 李显
1中国中医科学院西苑医院(北京,100091)
Author(s):
ZHANG Yandong1△; CAI Tongchuan1; LI Xian1
1Xiyuan Hospital,Chinese Academy of Traditional Chinese Medicine,Beijing 100091,China.
关键词:
急性踝关节扭伤;  消肿镇痛散;  超短波;  中西医结合;  气滞血瘀证;  距腓后韧带;  足背动脉;  血流动力学
Keywords:
acute ankle sprain;  Xiaozhong Zhentong powder;  ultra short wave;  integrative Chinese and Western medicine;  syndrome of Qi stagnation and blood stasis;  posterior talofibular ligament;  dorsalis pedis artery;  hemodynamics
分类号:
R684.7
DOI:
10.20085/j.cnki.issn1005-0205.260508
文献标志码:
A
摘要:
目的:基于中医“气滞血瘀”病机,验证消肿镇痛散外敷与超短波治疗联合应用的协同效应,明确其对急性踝关节扭伤患者距腓后韧带修复及足背动脉血流动力学的影响机制。方法:纳入118例72 h内发病且辨证属气滞血瘀证的急性踝关节扭伤患者,采用随机数字表法分为单一组(超短波治疗)和联合组(消肿镇痛散外敷+超短波治疗)各59例,疗程为2周。比较两组患者治疗前后踝关节疼痛视觉模拟量表(VAS)评分、踝关节周径、距腓后韧带厚度、足背动脉收缩期峰值血流速、平均血流速及血流阻力指数,并计算效应量。结果:两组患者治疗前VAS评分、踝关节周径、距腓后韧带厚度及收缩期峰值血流速等基线指标差异均无统计学意义(P>0.05),距腓后韧带厚度均约3.7 mm,收缩期峰值血流速均约2.9 cm/s。治疗2周后,联合组患者VAS评分由(7.07±0.87)分降至(1.32±0.34)分,踝关节周径由(41.25±2.77)cm降至(36.29±1.22)cm,均显著低于单一组,差异有统计学意义(P<0.001); 联合组患者距腓后韧带厚度较单一组多减少0.28 mm,差异有统计学意义(Cohen's d=0.89,P<0.001),收缩期峰值血流速较单一组多升高0.39 cm/s,差异有统计学意义(Cohen's d=0.92,P<0.001),同时平均血流速升高幅度更大、血流阻力指数下降更明显。机制上,联合方案通过“抗炎消肿-改善微循环-促进韧带修复”的协同作用,同时纠正距腓后韧带厚度异常和足背动脉血流障碍。结论:消肿镇痛散外敷联合超短波治疗可在短期内显著减轻急性踝关节扭伤患者急性期踝关节疼痛和肿胀,改善距腓后韧带结构修复和足背动脉血流动力学指标,为急性踝关节扭伤提供一种安全、有效的中西医结合治疗选择。安全性方面,两组患者均未发生严重不良事件,联合组患者出现轻度皮肤灼热感2例(3.39%),单一组患者出现短暂头晕1例(1.69%),均经对症处理后缓解。
Abstract:
Objective:Based on the traditional Chinese medicine(TCM)pathogenesis of Qi stagnation and blood stasis syndrome,to verify the synergistic effect of external application of Xiaozhong Zhentong powder(XZTS)and ultra short wave therapy in patients with acute ankle sprain(AAS),and to clarify its underlying mechanism in promoting posterior talofibular ligament(PTFL)repair and improving dorsal foot artery hemodynamics.Methods:A total of 118 patients with AAS within 72 h and diagnosed with the syndrome of Qi stagnation and blood stasis were randomly assigned(1:1)to single therapy group(ultra short wave alone)or combined therapy group(XZTS external application + ultra short wave),with 59 cases in each group,for a 2-weeks treatment course.Visual analogue scale(VAS)score,ankle circumference,PTFL thickness,peak systolic velocity(PSV),mean flow velocity(MFV)and resistance index(RI)of the dorsal foot artery were measured before and after treatment,and effect sizes(Cohen's d)were calculated.Results:At baseline,there were no significant differences in VAS score,ankle circumference,PTFL thickness(both about 3.7 mm)and PSV(both about 2.9 cm/s)between the two groups(all P>0.05).After 2 weeks of treatment,VAS score in the combined therapy group decreased from(7.07±0.87)points to(1.32±0.34)points,and ankle circumference decreased from(41.25±2.77)cm to(36.29±1.22)cm,both significantly lower than those in the single therapy group(P<0.001).Compared with the single therapy group,PTFL thickness in the combined therapy group showed an additional reduction of 0.28 mm(Cohen's d=0.89,P<0.001),while PSV increased by an additional 0.39 cm/s(Cohen's d=0.92,P<0.001),accompanied by a greater increase in MFV and a more pronounced decrease in RI.Mechanistically,the combined therapy regimen exerts a synergistic effect of “anti-inflammatory and anti-edema,improvement of microcirculation,and promotion of ligament repair”,thereby simultaneously correcting PTFL thickness abnormalities and dorsal foot artery blood flow disturbances.Conclusion:External application of XZTS combined with ultra short wave therapy can significantly relieve acute pain and swelling,improve PTFL structural repair and dorsal foot artery hemodynamics in patients with AAS,providing a safe and effective integrative TCM and Western medicine option for acute ankle sprain.No serious adverse events occurred during the study; mild skin burning was reported in 2 cases(3.39%)in the combined therapy group,and transient dizziness in 1 case(1.69%)in the single therapy group,all of which resolved after symptomatic management.

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(收稿日期:2025-11-01)

备注/Memo

备注/Memo:
基金项目:中国中医科学院西苑医院中医药临床科研一体化平台建设专项基金项目(XYZX0405-12)
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更新日期/Last Update: 2026-05-15