[1]谢志涛,陈欣志,张永涛,等.改良髓芯减压术联合骨形态发生蛋白活性诱导棒植入术治疗早期股骨头缺血性坏死的临床观察[J].中国中医骨伤科杂志,2026,34(04):54-59.[doi:10.20085/j.cnki.issn1005-0205.260409]
　XIE Zhitao,CHEN Xinzhi,ZHANG Yongtao,et al.Clinical Observation of Improved Porous Core Decompression Combined with Bone Morphogenetic Protein-Activated Inducing Rod Implantation for the Treatment of Early Ischemic Necrosis of the Femoral Head[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2026,34(04):54-59.[doi:10.20085/j.cnki.issn1005-0205.260409]
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改良髓芯减压术联合骨形态发生蛋白活性诱导棒植入术治疗早期股骨头缺血性坏死的临床观察()

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第34卷
期数:
2026年04期
页码:
54-59
栏目:
临床研究
出版日期:
2026-04-10

文章信息/Info

Title:
Clinical Observation of Improved Porous Core Decompression Combined with Bone Morphogenetic Protein-Activated Inducing Rod Implantation for the Treatment of Early Ischemic Necrosis of the Femoral Head
文章编号:
1005-0205(2026)04-0054-06
作者:
谢志涛1; 陈欣志1; 张永涛1; 田再杰1; 马智林1; 王珅1; 刘博宇1; 何全杰1; 褚兆珍1; 乔国勇1△
1河北工程大学附属医院(河北 邯郸,056004)
Author(s):
XIE Zhitao1; CHEN Xinzhi1; ZHANG Yongtao1; TIAN Zaijie1; MA Zhilin1; WANG Shen1; LIU Boyu1; HE Quanjie1; CHU Zhaozhen1; QIAO Guoyong1△
1Affiliated Hospital of Hebei University of Engineering,Handan 056004,Hebei China.
关键词:
改良髓芯减压术;  骨形成蛋白活性诱导棒植入术;  早期股骨头缺血性坏死
Keywords:
improved porous-core decompression surgery;  bone morphogenetic protein-inducing rod implantation surg-ery;  early-stage avascular necrosis of the femoral head
分类号:
R681.8
DOI:
10.20085/j.cnki.issn1005-0205.260409
文献标志码:
A
摘要:
目的:探究改良髓芯减压术(ACD)联合骨形态发生蛋白活性诱导棒植入术治疗早期股骨头缺血性坏死(ANFH)的临床疗效。方法:选取2022年5月至2024年6月就医的早期股骨头缺血性坏死患者80例,根据治疗方式分为减压术组(40例,髓芯减压术治疗)和联合组(40例,髓芯减压术+骨形态发生蛋白活性诱导棒植入术治疗)。比较两组患者术后的临床疗效、围手术期指标、疼痛视觉模拟量表(VAS)评分、Harris髋关节评分、骨代谢标志物及术后并发症。结果:术后联合组患者优良率为92.50%(37/40),高于减压术组的75.00%(30/40),差异有统计学意义(P<0.05)。两组患者的VAS评分较术前均降低,联合组低于减压术组,差异有统计学意义(P<0.05)。两组患者的Harris评分((86.32±18.38)分vs(78.14±15.25)分)、骨钙素(OC)、骨形态发生蛋白-2(BMP-2)水平较术前显著升高,且联合组显著高于减压术组,差异有统计学意义(P<0.05)。与联合组相比,减压术组患者的手术时间((62.12±7.10)min vs(52.12±6.20)min)明显缩短,术中出血量((132.10±15.60)mL vs(102.31±12.30)mL)减少,差异有统计学意义(P<0.05)。两组患者的术后并发症差异无统计学意义(P>0.05)。结论:采用改良髓芯减压术联合骨形态发生蛋白活性诱导棒植入术治疗股骨头缺血性坏死,能够提高优良率,降低VAS评分,提高Harris髋关节评分和骨代谢水平,安全性高。
Abstract:
Objective:To observe the clinical efficacy of early-stage avascular necrosis of the femoral head(ANFH)using modified porous core decompression combined with implantation of a bone morphogenetic protein-activating rod.Methods:From May 2022 to June 2024,80 patients with early ANFH who received medical treatment were grouped into the decompression group(40 cases,adopted improved porous core decompression)and the joint group(40 cases,adopted improved porous core decompression+bone morphogenetic protein activity induction rod implantation)complying with the treatment method.Two groups were compared in terms of postoperative clinical efficacy,perioperative indicators,pain visual analogue scale(VAS)score,Harris hip score,bone metabolism markers,and postoperative complications.Results:After surgery,the joint group had an excellent or good rate of 92.50%(37/40),which was significantly higher than that of the decompression group 75.00%(30/40)(P<0.05).Both groups showed a decrease in VAS scores after surgery,with the joint group exhibiting significantly lower scores than the decompression group(P< 0.05).Both groups had clearly increased Harris score((86.32±18.38)points vs(78.14±15.25)points),osteocalcin(OC),and bone morphogenetic protein-2(BMP-2)after surgery,with the joint group being clearly higher than the decompression group(P<0.05).For the joint group,the decompression group had significantly shorter surgical time((62.12±7.10)min vs(52.12±6.20)min)and less intraoperative bleeding((132.10±15.60)mL vs(102.31±12.30)mL)(P<0.05).The postoperative complications were not clearly different between two groups(P>0.05).Conclusion:The joint use of improved porous core decompression with bone morphogenetic protein activity induction rod implantation for ANFH can improve the excellent rate of patients.It can reduce VAS score,improve Harris hip score and bone metabolism,and has high safety.

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(收稿日期:2025-03-26)

备注/Memo

备注/Memo:
基金项目:河北省卫生健康委员会资助项目(20220656)
△通信作者 E-mail:prxfdn@163.com
更新日期/Last Update: 2026-04-15