[1]林顺,姜宏,王志强,等.益气活血方治疗腰椎间盘突出症内镜术后残留症状疗效的单臂队列研究[J].中国中医骨伤科杂志,2026,34(03):65-71.[doi:10.20085/j.cnki.issn1005-0205.260310]
 LIN Shun,JIANG Hong,WANG Zhiqiang,et al.A Single-Arm Cohort Study on the Efficacy of Yiqi Huoxue Formula in Treating Residual Symptoms after Endoscopic Surgery for Lumbar Disc Herniation[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2026,34(03):65-71.[doi:10.20085/j.cnki.issn1005-0205.260310]
点击复制

益气活血方治疗腰椎间盘突出症内镜术后残留症状疗效的单臂队列研究()

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第34卷
期数:
2026年03期
页码:
65-71
栏目:
临床研究
出版日期:
2026-03-15

文章信息/Info

Title:
A Single-Arm Cohort Study on the Efficacy of Yiqi Huoxue Formula in Treating Residual Symptoms after Endoscopic Surgery for Lumbar Disc Herniation
文章编号:
1005-0205(2026)03-0065-07
作者:
林顺1姜宏1王志强1龚冠亦1李晓春1俞鹏飞1马智佳1刘锦涛1戴锋1△
1南京中医药大学附属苏州市中医医院(江苏 苏州,215000)
Author(s):
LIN Shun1JIANG Hong1WANG Zhiqiang1GONG Guanyi1LI Xiaochun1YU Pengfei1MA Zhijia1LIU Jintao1DAI Feng1△
1Suzhou Hospital of Traditianal Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Suzhou 215000,Jiangsu China.
关键词:
腰椎间盘突出症 内镜术后残留症状 益气活血方 单臂队列研究
Keywords:
lumbar disc herniation residual symptoms after endoscopic surgery Yiqi Huoxue formula single-arm cohort study
分类号:
R681.5
DOI:
10.20085/j.cnki.issn1005-0205.260310
文献标志码:
A
摘要:
目的:基于MRI探讨益气活血方治疗脱出与游离型腰椎间盘突出症内镜术后残留症状的预后转归。方法:收集2019年1月至2024年12月治疗的44例脱出与游离型腰椎间盘突出症内镜术后残留症状患者资料,统计患者性别、年龄、病程、责任节段等信息,记录患者治疗前与治疗后1个月、3个月、6个月日本骨科协会(JOA)评分与疼痛视觉模拟量表(VAS)评分,统计治疗前及治疗3个月后残留突出组织体积的变化,探讨益气活血方治疗腰椎间盘突出症内镜术后残留症状的临床疗效。结果:益气活血方可实现脱出与游离型腰椎间盘突症内镜术后残留症状的缓解并促进术后残留突出组织重吸收,而术后血肿组较术后残留组临床症状改善更迅速,术后残留组织重吸收有利于术后残留症状的缓解。结论:益气活血方可实现内镜术后残留症状的缓解,促成术后残留组织的重吸收,且残留组织重吸收对症状缓解有积极意义。
Abstract:
Objective:To evaluate the prognosis and outcomes of the Yiqi Huoxue formula in treating residual symptoms after endoscopic surgery for protruded and sequestrated lumbar intervertebral disc herniation,based on MRI findinds.Methods:A total of 44 patients with residual symptoms after endoscopic surgery for protruded and sequestrated lumbar intervertebral disc herniation,who were treated from January 2019 to December 2024,were enrolled.The patients' gender,age,disease duration,and affected segments were statistically collected.The Japanese orthopaedic association(JOA)scores and visual analogue scale(VAS)scores of the patients before treatment and at 1 month,3 months,and 6 months after treatment were recorded.The changes in the volume of residual protruded tissue before treatment and 3 months after treatment were statistically analyzed to explore the clinical efficacy of the Yiqi Huoxue formula in treating residual symptoms following endoscopic surgery.Results:The Yiqi Huoxue formula can relieve residual symptoms after endoscopic surgery for protruded and sequestrated lumbar intervertebral disc herniation and promote the reabsorption of residual protruding tissue.The clinical symptoms of the postoperative hematoma group improved more rapidly than those of the postoperative residual group.The reabsorption of residual tissue after surgery is conducive to the relief of residual symptoms.Conclusion:The Yiqi Huoxue formula can relieve residual symptoms after endoscopic surgery and promote the reabsorption of residual tissue postsurgery.The reabsorption of residual tissue has a positive significance for the relief of symptoms.

参考文献/References:

[1] 刘欢,徐用亿,陈晓钢,等.内镜椎间盘切除联合激素治疗L5S1椎间盘脱出症[J].中国矫形外科杂志,2021,29(24):2235-2240.
[2] 刘滔,周全,章君鑫,等.内镜与开放手术治疗腰神经根管狭窄症比较[J].中国矫形外科杂志,2021,29(24):2230-2234.
[3] EUN S S,LEE S H,SABAL L A.Long-term follow-up results of percutaneous endoscopic lumbar discectomy[J].Pain Physician,2016,19(8):E1161-E1166.
[4] CHOI K C,LEE J H,KIM J S,et al.Unsuccessful percutaneous endoscopic lumbar discectomy:a single-center experience of 10 228 cases[J].Neurosurgery,2015,76(4):372-381.
[5] LIANG J Q,CHEN C,ZHAO H.Revision surgery after percutaneous endoscopic transforaminal discectomy compared with primary open surgery for symptomatic lumbar degenerative disease[J].Orthopaedic Surgery,2019,11(4):620-627.
[6] WANG S J,ZHANG S B,YI Y Y,et al.Estimation of the ideal correction of lumbar lordosis to prevent reoperation for symptomatic adjacent segment disease after lumbar fusion in older people[J].BMC Musculoskeletal Disorders,2020,21(1):429.
[7] YOSHIKANE K,KIKUCHI K,IZUMI T,et al.Full-endoscopic lumbar discectomy for recurrent lumbar disc herniation:a retrospective study with patient-reported outcome measures[J].Spine Surgery and Related Research,2020,5(4):272-277.
[8] 戎毅,马勇,郭杨,等.中医药治疗腰椎间盘突出症微创术后残留症状的研究进展[J].中华中医药杂志,2021,36(5):2830-2834.
[9] 李凯明,王尚全,李玲慧,等.身痛逐瘀汤治疗腰椎间盘突出症疗效与安全性的Meta分析[J].时珍国医国药,2020,31(2):490-495.
[10] 丁秀芳,孙丽双,王英华,等.电针治疗腰椎间盘突出症椎间孔镜术后残留症状[J].中国矫形外科杂志,2020,28(23):2158-2161.
[11] 洪政茹,朱亮亮,常裕绅,等.正清风痛宁定向透药联合塞来昔布治疗腰椎间盘突出症的临床疗效[J].中医药导报,2023,29(5):99-102.
[12] 高燕,陈旭龙,黄彬城,等.岭南陈氏针法治疗腰椎间盘突出症的临床观察[J].中医药导报,2023,29(3):98-101.
[13] 中华医学会疼痛学分会脊柱源性疼痛学组.腰椎间盘突出症诊疗中国疼痛专家共识[J].中国疼痛医学杂志,2020,26(1):2-6.
[14] KREINER D S,HWANG S W,EASA J E,et al.An evidence-based clinical guideline for the diagnosis and treatment of lumbar disc herniation with radiculopathy[J].The Spine Journal,2014,14(1):180-191.
[15] APPEL B.Nomenclature and classification of lumbar disc pathology[J].Rivista Di Neuroradiologia,2001,14(2):147-151.
[16] FARDON D F,WILLIAMS A L,DOHRING E J,et al.Lumbar disc nomenclature:version 2.0:recommendations of the combined task forces of the North American Spine Society,the American Society of Spine Radiology and the American Society of Neuroradiology[J].The Spine Journal,2014,14(11):2525-2545.
[17] 俞鹏飞,姜宏,马智佳,等.增强MRI对脱出和游离型腰椎间盘突出症转归的预测价值[J].中华骨科杂志,2021,41(18):1350-1360.
[18] AZIMI P,MOHAMMADI H R,MONTAZERI A.An outcome measure of functionality and pain in patients with lumbar disc herniation:a validation study of the Japanese orthopedic association(JOA)score[J].Journal of Orthopaedic Science,2012,17(4):341-345.
[19] HUSKISSON E C.Measurement of pain[J].The Lancet,1974,304(7889):1127-1131.
[20] 戴宇祥,姜宏.基于内容分析法的腰椎间盘突出重吸收影响因素分析[J].颈腰痛杂志,2019,40(5):583-586.
[21] YU P F,MAO F,CHEN J Y,et al.Characteristics and mechanisms of resorption in lumbar disc herniation[J].Arthritis Research & Therapy,2022,24(1):205.
[22] KIM C H,CHUNG C K,CHOI Y,et al.The long-term reoperation rate following surgery for lumbar herniated intervertebral disc disease:a nationwide sample cohort study with a 10-year follow-up[J].Spine,2019,44(19):1382-1389.
[23] ZHAO R Z,LIU W Q,WANG M Y,et al.Lysyl oxidase inhibits TNF-α induced rat nucleus pulposus cell apoptosis via regulating Fas/FasL pathway and the p53 pathways[J].Life Sciences,2020,260:118483.
[24] GUO Y J,PAN W W,LIU S B,et al.ERK/MAPK signalling pathway and tumorigenesis[J].Experimental and Therapeutic Medicine,2020,19(3):1997-2007.
[25] DAI F,DAI Y X,JIANG H,et al.Non-surgical treatment with XSHHD for ruptured lumbar disc herniation:a 3-year prospective observational study[J].BMC Musculoskeletal Disorders,2020,21(1):690.
[26] 沈学强,姜宏.姜宏教授辨治巨大游离型腰椎间盘突出症经验介绍[J].中国中医骨伤科杂志,2018,26(7):78-80.
[27] 刁志君,姜宏,刘锦涛.细胞自噬对腰椎间盘突出后重吸收的意义[J].中国骨伤,2018,31(4):386-390.
(收稿日期:2025-08-05)

备注/Memo

备注/Memo:
基金项目:国家自然科学基金项目(82474529,82374220)
江苏省中医药科技发展项目(MS2022080,QN202222,H2023059)
第三批江苏省中医药领军人才项目(苏中医科教〔2023〕9号)
江苏省科教能力提升工程:江苏省医学重点学科/实验室建设单位(苏卫科教〔2022〕17号)
中医骨伤重点实验室建设项目(SZS2022019)
苏州市科技发展计划(SKYD2023151,SKYD2023152)
苏州市“科教兴卫”青年科技项目(K
更新日期/Last Update: 2026-03-15