[1]郑林燕,葛继荣△,谢丽华,等.失眠对绝经后女性骨密度的影响[J].中国中医骨伤科杂志,2026,34(02):78-82.[doi:10.20085/j.cnki.issn1005-0205.260213]
　ZHENG Linyan,GE Jirong,XIE Lihua,et al.The Influence of Insomnia on Bone Mineral Density in Postmenopausal Women[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2026,34(02):78-82.[doi:10.20085/j.cnki.issn1005-0205.260213]
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失眠对绝经后女性骨密度的影响()

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第34卷
期数:
2026年02期
页码:
78-82
栏目:
临床研究
出版日期:
2026-02-15

文章信息/Info

Title:
The Influence of Insomnia on Bone Mineral Density in Postmenopausal Women
文章编号:
1005-0205(2026)02-0078-05
作者:
郑林燕1; 葛继荣2; 3△; 谢丽华2; 3; 李玉乐1
1福建中医药大学(福州,350003);2福建省中医药科学院基础研究所;3福建省中西医结合防治骨质疏松重点实验室(福建省中医药科学院,福建中医药大学附属康复医院)
Author(s):
ZHENG Linyan1; GE Jirong2; 3△; XIE Lihua2; 3; LI Yule1
1Fujian University of Traditional Chinese Medicine,Fuzhou 350003,China; 2Institute of Basic Research,Fujian Academy of Chinese Medical Sciences,Fuzhou 350003,China; 3Fujian Key Laboratory of Integrated Traditional Chinese and Western Medicine for the Prevention and Treatment of Osteoporosis(Fujian Academy of Chinese Medical Sciences,Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine),Fuzhou 350003,China.
关键词:
入睡和睡眠障碍;  骨质疏松;  绝经后;  骨密度;  腰椎;  体重指数
Keywords:
sleep initiation and maintenance disorders;  osteoporosis;  postmenopausal;  bone mineral density;  lumbar vertebrae;  body mass index(BMI)
分类号:
R681
DOI:
10.20085/j.cnki.issn1005-0205.260213
文献标志码:
A
摘要:
目的:揭示失眠对绝经后女性骨密度(BMD)的影响。方法:通过回顾性病例对照研究,从2017年1月1日至2024年4月30日,在参加问卷调查和骨密度检测的绝经后女性中,纳入符合标准的患者,运用SPSS 26.0进行统计分析。结果:对比失眠组与无失眠组,体重和体重指数(BMI)差异有统计学意义(P<0.05),而年龄、月经初潮年龄、怀孕次数等一般资料差异均无统计学意义(P<0.05); 失眠组腰椎T值显著低于无失眠组,差异有统计学意义(P<0.05); 失眠组骨量丢失率高于无失眠组,差异有统计学意义(P<0.05),骨量正常率低于无失眠组,差异有统计学意义(P<0.05); 单、多因素Logistic回归分析结果显示失眠、年龄、怀孕次数是骨量丢失的危险因素,差异有统计学意义(P<0.05),而正常的体重指数是保护因素,差异有统计学意义(P<0.05)。结论:失眠可能是影响绝经后女性骨密度的一种危险因素,失眠的绝经后女性存在腰椎低骨密度的风险。
Abstract:
Objective:This study aims to reveal the impact of insomnia on bone mineral density(BMD)in postmenopausal women.Methods:A retrospective case-control study was conducted among postmenopausal women who participated in questionnaire surveys and BMD tests from January 1,2017 to April 30,2024.Patients meeting the inclusion criteria were included.Statistical analysis was performed using SPSS 26.0.Results:There were no statistically significant differences in age,the age of menarche,the number of pregnancies,the number of children breastfed,the age at menopause,and the height between the insomnia group and the non-insomnia group.However,there were statistically significant differences in weight and body mass index(BMI)(P<0.05).The T value of the lumbar spine in the insomnia group was significantly lower than that in the non-insomnia group(P<0.05),and the BMD of the lumbar spine was also lower.Bone mass loss occurred at a faster pace in the insomnia group than in the non-insomnia group(P<0.05),and the percentage of normal bone mass was lower in the insomnia group(P<0.05).The results of univariate and multivariate Logistic regression analysis showed that insomnia,age and the number of pregnancies were risk factors for bone loss(P<0.05),while BMI was a protective factor(P<0.05).Conclusion:Insomnia may be a risk factor for BMD in postmenopausal women,and postmenopausal women with insomnia are at risk of low BMD in the lumbar spine.

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(收稿日期:2025-05-30)

备注/Memo

备注/Memo:
基金项目:国家自然科学基金项目(81674007,82274563,82374483)
国家中医药管理局高水平中医药重点学科建设项目(中医骨伤科学)(zyyzdxk-2023106)
福建中医药大学中医骨伤科学学科开放课题资助(XGS2023001)
福建省科技厅省属公益类科研院所基本科研专项(2022R1003002)
△通信作者 E-mail:gjrrjgcy@163.com
更新日期/Last Update: 2026-02-15