[1]李悠悠,张文琦,陈启鹏,等.易筋经联合富血小板血浆治疗膝骨关节炎[J].中国中医骨伤科杂志,2026,34(02):47-52.[doi:10.20085/j.cnki.issn1005-0205.260207]
　LI Youyou,ZHANG Wenqi,CHEN Qipeng,et al.Yi Jin Jing Combined with Platelet-Rich Plasma for Knee Osteoarthritis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2026,34(02):47-52.[doi:10.20085/j.cnki.issn1005-0205.260207]
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易筋经联合富血小板血浆治疗膝骨关节炎()

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第34卷
期数:
2026年02期
页码:
47-52
栏目:
临床研究
出版日期:
2026-02-15

文章信息/Info

Title:
Yi Jin Jing Combined with Platelet-Rich Plasma for Knee Osteoarthritis
文章编号:
1005-0205(2026)02-0047-06
作者:
李悠悠1; 张文琦2; 陈启鹏2; 贺琳钦2; 唐宗瀚1; 宋寒冰2△
1黑龙江中医药大学(哈尔滨,150040);2黑龙江中医药大学附属第一医院
Author(s):
LI Youyou1; ZHANG Wenqi2; CHEN Qipeng2; HE Linqin2; TANG Zonghan1; SONG Hanbing2△
1Heilongjiang University of Chinese Medicine,Harbin 150040,China; 2The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China.
关键词:
易筋经;  富血小板血浆;  股四头肌等长肌力训练;  膝骨关节炎
Keywords:
Yi Jin Jing;  platelet-rich plasma;  quadriceps isometric muscle training;  knee osteoarthritis
分类号:
R684.3
DOI:
10.20085/j.cnki.issn1005-0205.260207
文献标志码:
A
摘要:
目的:探讨易筋经联合富血小板血浆(PRP)治疗膝骨关节炎(KOA)的临床疗效。方法:60例膝骨关节炎患者随机分为观察组和对照组,对照组30例采用股四头肌等长肌力训练联合富血小板血浆治疗,观察组30例采用易筋经联合富血小板血浆治疗,两组患者连续治疗3个月。3个月为1个疗程,共治疗1个疗程。比较两组患者的临床疗效及复发率,治疗前后的VAS评分及WOMAC评分,炎症因子IL-1β、MMP-3、TNF-α水平,以及膝关节肌骨超声检查结果。结果:治疗后观察组总有效率96.67%(29/30)显著高于对照组46.67%(14/30),且显效率76.67%(23/30)明显优于对照组26.67%(8/30),差异有统计学意义(P<0.05)。观察组复发率显著低于对照组,差异有统计学意义(P<0.05)。观察组VAS评分及WOMAC评分,炎症因子IL-1β、MMP-3、TNF-α水平,超声下滑膜厚度和积液深度均下降,差异有统计学意义(P<0.05),且观察组显著优于对照组,差异有统计学意义(P<0.05)。两组患者均无不良事件发生。结论:易筋经联合富血小板血浆治疗膝骨关节炎可减轻关节疼痛、僵硬,提高关节功能,减轻炎症反应,降低复发率,临床疗效显著,安全性较高,适合临床推广应用。
Abstract:
Objective:To undertake a rigorous clinical study to assess the therapeutic efficacy of combining Yi Jin Jing exercises with platelet-rich plasma(PRP)in the management of patients with knee osteoarthritis(KOA).Methods:Sixty patients diagnosed with KOA were randomly allocated into two groups of 30 each(control group and observation group).The observation group underwent Yi Jin Jing exercises combined with PRP therapy,whereas the control group participated in isometric quadriceps muscle strengthening exercises paired with PRP therapy,and 30 cases in the observation group were treated with Yi Jin Jing combined with PRP,and the two groups were treated consecutively for 3 months.3 months was 1 course of treatment,and a total of 1 course of treatment was given.The clinical efficacy and recurrence rate of the two groups were compared,as well as the VAS scores,WOMAC scores,levels of inflammatory factors(IL-1β,MMP-3,and TNF-α),and musculoskeletal ultrasound results of the knee joint before and after treatment.Results:Compared to the control group's 46.67% effectiveness(14/30),the observation group achieved 96.67% efficacy(29/30).A significant improvement was observed in 76.67% of observation group(23/30)versus only 26.67%(8/30)in control group,with the observation group also demonstrating significantly reduced recurrence(P<0.05).VAS scores,WOMAC scores,levels of inflammatory factors IL-1β,MMP-3,TNF-α,synovial thickness and effusion depth decreased in the observation group(P<0.05),and the observation group was significantly better than the control group(P<0.05).No adverse events occurred in both groups.Conclusion:It shows that Yi Jin Jing combined with PRP treatment for KOA can reduce the joint pain and stiffness,improve joint function,reduce the inflammatory response,lower the recurrence rate,and achieve remarkable clinical efficacy with high safety,making it suitable for clinical promotion.

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(收稿日期:2025-08-02)

备注/Memo

备注/Memo:
基金项目:黑龙江省自然科学基金优秀青年基金项目(YQ2020H028)
黑龙江省自然科学基金项目(PL2024H217)
△通信作者 E-mail:songhanbing@hljucm.edu.cn
更新日期/Last Update: 2026-02-15