[1]彭啸,刘治泽,燕锡童,等.基于德尔菲法的肌少症中医四诊信息辨识体系构建[J].中国中医骨伤科杂志,2026,34(01):101-106.[doi:10.20085/j.cnki.issn1005-0205.260114]
 PENG Xiao,LIU Zhize,YAN Xitong,et al.A Delphi Study to Establish a Diagnostic Framework for Sarcopenia in Traditional Chinese Medicine[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2026,34(01):101-106.[doi:10.20085/j.cnki.issn1005-0205.260114]
点击复制

基于德尔菲法的肌少症中医四诊信息辨识体系构建()

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第34卷
期数:
2026年01期
页码:
101-106
栏目:
肌少症
出版日期:
2026-01-15

文章信息/Info

Title:
A Delphi Study to Establish a Diagnostic Framework for Sarcopenia in Traditional Chinese Medicine
文章编号:
1005-0205(2026)01-0101-06
作者:
彭啸12刘治泽12燕锡童1张志文3王达1郑力铭1金子开1朱立国1李玲慧14△魏戌14△
1中国中医科学院望京医院(北京,100102)
2北京中医药大学
3湖北省中医院(湖北中医药大学附属医院)
4数智中医防治骨与关节退行性疾病北京市重点实验室
Author(s):
PENG Xiao12LIU Zhize12YAN Xitong1ZHANG Zhiwen3WANG Da1ZHENG Liming1JIN Zikai1ZHU Liguo1LI Linghui14△WEI Xu14△
1Wangjing Hospital of China Academy of Chinese Medical Sciences,Beijing 100102,China; 2Beijing University of Chinese Medicine,Beijing 100029,China; 3Hubei Provincial Hospital of Traditional Chinese Medicine,Affiliated Hospital of Hubei University of Chinese Medicine,Wuhan 430060,China; 4Beijing Key Laboratory of Digital Intelligence Traditional Chinese Medicine for Prevention and Treatment of Bone and Joint Degenerative Diseases,Beijing 100102,China.
关键词:
肌少症 德尔菲法 中医四诊信息 证候辨识
Keywords:
sarcopenia Delphi method four diagnostic methods of TCM syndrome differentiation
分类号:
R685
DOI:
10.20085/j.cnki.issn1005-0205.260114
文献标志码:
A
摘要:
目的:构建规范、实用的肌少症中医四诊信息辨识工具,为肌少症中医辨证分型及临床诊疗提供标准化参考工具。方法:结合文献研究、半结构化访谈与头脑风暴法,系统梳理肌少症中医四诊相关信息,初步构建初始条目池; 遴选中医骨伤科学、中医诊断学、方法学、统计学、中西医结合等领域权威专家,采用德尔菲法开展两轮专家咨询,以重要性评分、变异系数、满分率为核心筛选指标,结合专家修订意见优化条目,最终确立辨识体系框架及核心内容; 通过信度分析验证体系可靠性。结果:研究构建了包含823个条目的初始条目池,经初筛后形成包含214个条目的第一轮德尔菲咨询问卷。依据专家反馈修订后,形成含136个条目的第二轮问卷; 进一步剔除5个不符合筛选标准的条目,最终确立包含发病因素9项、临床症状90项(主证6项、兼证84项)、舌象21项、脉象11项,共计131个条目的辨识体系。两轮咨询各回收有效问卷25份,累计50份,25位受邀专家全程参与,专家积极系数均为100%,权威系数分别为0.892和0.900。结论:本研究构建的肌少症中医四诊信息辨识体系具有良好的科学性、权威性和实用性,可为临床规范化采集肌少症中医四诊信息、精准辨证提供可靠参考工具。
Abstract:
Objective:To establish a standardized tool for extracting information from the four diagnostic methods of traditional Chinese medicine(TCM)in patients with sarcopenia,thereby providing a reference for TCM syndrome differentiation and clinical practice.Methods:An initial item pool was constructed through a systematic process integrating literature review,semi-structured interviews,and brainstorming.Experts were purposively sampled from key disciplines,including TCM orthopedics,TCM diagnostics,and methodology.A two-round Delphi consultation was conducted.Items were refined based on importance scores,the coefficient of variation,and the full-score ratio,with the final selection determined by expert consensus and statistical thresholds.The reliability of the finalized framework was analyzed.Results:From an initial pool of 823 items,a first-round questionnaire comprising 214 items was formulated.After expert evaluation,a second-round questionnaire containing 136 items was administered.Subsequently,5 items that failing to meet the screening criteria were excluded,leading to the finalization of a diagnostic system encompassing 131 items:9 on pathogenic factors,90 on clinical symptoms(6 primary and 84 concurrent),21 on tongue signs,and 11 on pulse signs.Across the two Delphi rounds,50 valid questionnaires were retrieved,with 25 experts participating consistently.The response rate reached 100% in both rounds,and the expert authority coefficients were 0.892 and 0.900,respectively.Conclusion:The established TCM Four Diagnostic Methods-based identification system for sarcopenia exhibits high scientific rigor,strong credibility based on expert consensus,and good clinical applicability.It constitutes a reliable and standardized tool for collecting TCM diagnostic data and facilitating accurate syndrome differentiation in the management of sarcopenia.

参考文献/References:

[1] FIELDING R A,VELLAS B,EVANS W J,et al.Sarcopenia:an undiagnosed condition in older adults.Current consensus definition:prevalence,etiology,and consequences.International working group on sarcopenia[J].Journal of the American Medical Directors Association,2011,12(4):249-256.
[2] DENT E,MORLEY J E,CRUZ-JENTOFT A J,et al.International clinical practice guidelines for sarcopenia(ICFSR):screening,diagnosis and management[J].The Journal of Nutrition,Health and Aging,2018,22(10):1148-1161.
[3] CHEN L K,WOO J,ASSANTACHAI P,et al.Asian working group for sarcopenia:2019 consensus update on sarcopenia diagnosis and treatment[J].Journal of the American Medical Directors Association,2020,21(3):300-307.e2.
[4] BISCHOFF-FERRARI H A,ORAV J E,KANIS J A,et al.Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older[J].Osteoporosis International,2015,26(12):2793-2802.
[5] CHEN L K,HSIAO F Y,AKISHITA M,et al.A focus shift from sarcopenia to muscle health in the Asian Working Group for Sarcopenia 2025 Consensus Update[J].Nat Aging,2025,5(11):2164-2175.
[6] CRUZ-JENTOFT A J,BAHAT G,BAUER J,et al.Sarcopenia:revised European consensus on definition and diagnosis[J].Age Ageing,2019,48(4):601.
[7] 魏巍,戚晓楠,谢鹏,等.中医药治疗肌少症的方法及其作用机制研究最新进展[J].世界中医药,2024,19(20):3191-3198.
[8] 梁清月,王仲,刘戎,等.加减八珍汤联合营养支持治疗老年骨骼肌减少症疗效观察[J].中国中西医结合杂志,2019,39(7):821-825.
[9] 温春瑜,陈颖颖,彭鹏,等.补中益气汤加减辅助治疗老年肌少症的临床疗效观察[J].实用中西医结合临床,2018,18(7):72-73.
[10] 张艳丽,宋昳星,徐丹.三子养亲汤加减联合针刺对慢性阻塞性肺疾病稳定期合并肌少症患者的临床疗效[J].中成药,2024,46(1):107-111.
[11] 李玲慧,郑力铭,田纪祥,等.中医药防治肌少症的关键问题、诊治优势与研究模式探索[J].世界中医药,2025,20(18):2413-2418.
[12] 田金洲,王永炎,时晶,等.证候的概念及其属性[J].北京中医药大学学报,2005,28(5):6-8.
[13] 张莹莹,王佳佳,李建生,等.中医证候诊断量表文献研究现状[J].中医杂志,2025,66(17):1810-1816.
[14] 俞柏翎,李娟,叶茂盛,等.肌肉减少症的中医病名探讨[J].中华中医药杂志,2022,37(10):6105-6107.
[15] 王达,秦晓宽,彭啸,等.肌少症专家共识与循证指南的多维方法学质量评价与综合分析[J].世界中医药,2025,20(18):2432-2440.
[16] 刘晓雨,刘志华,李京璠,等.浊毒证诊断量表的研制与权重赋值——基于德尔菲法及层次分析法[J].中医杂志,2024,65(7):684-690.
[17] 庞湃,王斌,吴深涛,等.2型糖尿病浊毒内蕴证中医诊断量表的研制及验证[J].中医杂志,2024,65(2):159-166.
[18] 李涵,张明雪,曲淼,等.基于象思维的冠心病合并病中医证候专家问卷研制与评价[J].中华中医药杂志,2016,31(1):175-177.
[19] 李建生,冯贞贞,谢洋,等.病证结合模式下中医证候疗效评价量表研制的实践与策略[J].中国全科医学,2022,25(20):2513-2519.
[20] 世界中医药学会联合会,呼吸疾病中医药防治省部共建协同创新中心,河南中医药大学,等.中医证候诊断标准研制指南[J].中国循证医学杂志,2023,23(9):993-998.
[21] 国家卫生健康委员会,国家中医药管理局.中医临床诊疗术语 第2部分:证候[M].北京:中国中医药出版社,2020.
[22] 孙继高,傅繁誉,王荣田,等.基于德尔菲法的骨质疏松高风险人群中医症状辨识研究[J].中国中医基础医学杂志,2021,27(5):792-795.
[23] 王晶亚,宗星煜,王丁熠,等.中医药国际标准实施效果评价指标体系构建研究[J].中国中医基础医学杂志,2023,29(1):99-103.
[24] 魏戌,尹煜辉,王旭,等.基层医疗卫生机构骨健康服务能力评价指标体系研究[J].中国全科医学,2025,28(19):2354-2362.
[25] 侍磊,王文章.糖尿病肌少症的中医药研究进展[J].中医药临床杂志,2020,32(8):1588-1591.
[26] 吴正治.老年肌肉衰减综合征中西结合诊治概况与研究展望[J].中国中西医结合杂志,2021,41(9):1029-1031.
[27] 董秀娟.重症肌无力中医证治的文献资料整理研究[D].广州:广州中医药大学,2012.
[28] 姜德友,周雪明.虚劳病源流考[J].四川中医,2007,25(12):31-33.
[29] 杜来义,黄捷,汪桂青,等.肌肉减少症的中西医诊治与探讨[J].中医学报,2020,35(7):1420-1423.
[30] 薛泰骑.老年肌少症中医证素、证候分布特征研究[D].北京:北京中医药大学,2022.
[31] 黄馨懿,郑力铭,李韵宁,等.肌少症及其共病的中医药防治策略与未来研究方向[J].世界中医药,2025,20(18):2419-2424.
[32] 宋一帆,韩庆烽,肖卫忠,等.基于德尔菲法的全科住院医师临床思维能力评价体系构建研究[J].中国全科医学,2025,28(1):77-82.
(收稿日期:2025-11-24)

备注/Memo

备注/Memo:
基金项目:国家中医药多学科交叉创新团队项目(ZYYCXTD-D-202401)
中国中医科学院卓越青年科技人才培养专项(CI2024D003)
中国中医科学院优秀青年科技人才培养专项(ZZ17-YQ-014)
通信作者 E-mail:postdoctorli@163.com(李玲慧)
weixu.007@163.com(魏戌)
更新日期/Last Update: 2026-01-15