[1]张同会,李涛,唐谨,等.两种不同介质的微创融合术治疗单节段腰椎退变性疾病的临床研究[J].中国中医骨伤科杂志,2025,33(11):51-57.[doi:10.20085/j.cnki.issn1005-0205.251110]
 ZHANG Tonghui,LI Tao,TANG Jin,et al.Clinical Study of Minimally Invasive Surgery in the Treatment of Single-Segment Lumbar Degenerative Disease with Two Different Media[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2025,33(11):51-57.[doi:10.20085/j.cnki.issn1005-0205.251110]
点击复制

两种不同介质的微创融合术治疗单节段腰椎退变性疾病的临床研究()

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第33卷
期数:
2025年11期
页码:
51-57
栏目:
临床研究
出版日期:
2025-11-15

文章信息/Info

Title:
Clinical Study of Minimally Invasive Surgery in the Treatment of Single-Segment Lumbar Degenerative Disease with Two Different Media
文章编号:
1005-0205(2025)11-0051-07
作者:
张同会12李涛2唐谨2戢鹏2黄荷2赵宙2徐峰1△
1湖北中医药大学针灸骨伤学院(武汉,430070)
2武汉中西医结合骨科医院(武汉体育学院附属医院)
Author(s):
ZHANG Tonghui12LI Tao2TANG Jin2JI Peng2HUANG He2ZHAO Zhou2XU Feng1△
1School of Acupuncture and Orthopedics,Hubei University of Chinese Medicine,Wuhan 430070,China; 2Wuhan Hospital of Integrated Chinese and Western Medicine Orthopedics(Affiliated Hospital of Wuhan Sports University),Wuhan 430070,China.
关键词:
单节段腰椎退变性疾病 经皮内镜下后路腰椎融合术 可扩张通道辅助下腰椎后路融合术
Keywords:
single level lumbar degenerative disease percutaneous endoscopic posterior lumbar interbody fusion minimally invasive posterior lumbar interbody fusion
分类号:
R681.5
DOI:
10.20085/j.cnki.issn1005-0205.251110
文献标志码:
A
摘要:
目的:比较水介质下经皮内镜后路腰椎融合术(PE-PLIF)与空气介质下可扩张通道辅助的后路腰椎融合术(MIS-PLIF)的临床疗效。方法:回顾性分析自2021年11月至2024 年1月采用微创融合技术治疗的单节段腰椎间盘突出症患者58例,其中行PE-PLIF手术30例,行MIS-PLIF手术28例。统计两组患者基本资料、围手术期临床数据和影像学参数,通过视觉模拟量表(VAS)评分和 Oswestry功能障碍指数(ODI)评分评估临床结果。结果:两组患者均顺利完成手术,无严重并发症发生,所有患者均随访12个月。与MIS-PLIF组相比,PE-PLIF组手术时间长、切口长度短、术中出血量少、术后引流量少、隐性失血量少、术后至下床时间短,差异均有统计学意义(P<0.05); 比较切口愈合等级及下肢深静脉血栓的发生率,差异无统计学意义(P>0.05)。出院时随访PE-PLIF组VAS 评分及ODI评分优于MIS-PLIF组,差异有统计学意义(P<0.05)。影像学表现与术前相比,术后6 个月和末次随访时,两组患者椎间隙高度、腰椎前凸角均显著增加,差异有统计学意义(P<0.05),相应时间点两组间的差异均无统计学意义(P>0.05)。此外,相应时间点两组间 Bridwell 融合分级差异也无统计学意义(P>0.05)。结论:PE-PLIF手术较MIS-PLIF手术损伤更小,出血量少,术后恢复快,近期腰椎功能恢复更佳,远期疗效相当。
Abstract:
Objective:To compare the effects of percutaneous endoscopic posterior lumbar interbody fusion(PE-PLIF)with aqueous media and minimally invasive posterior lumbar interbody fusion(MIS-PLIF)assisted by expandable channel under air medium.Methods:A retrospective analysis was conducted on 58 cases of single-level lumbar disc herniation treated with a minimally invasive fusion technique from November 2021 to January 2024,of which 30 cases underwent PE-PLIF and 28 cases underwent MIS-PLIF.The basic data,perioperative clinical data,and radiological parameters of the two groups were statistically analyzed.The clinical outcomes were assessed using the visual analogue scale(VAS)and Oswestry disability index(ODI)scores.Results:All procedures were successfully completed without major complications,with 12 months follow-up.The PE-PLIF group demonstrated significantly longer operative time but superior outcomes in incision length,blood loss(intraopera-tive/postoperative/hidden),and earlier ambulation versus MIS-PLIF(all P<0.05).No intergroup differences existed in wound healing or deep vein thrombosis(DVT)incidence(P>0.05).At discharge,PE-PLIF showed better VAS and ODI scores(P<0.05).Both groups exhibited improved intervertebral space height and lordosis postoperatively(P<0.05 vs preoperative),with no intergroup differences at any follow-up(P>0.05).Furthermore,there was no notable disparity in Bridwell fusion grade between the two groups at corresponding time points(P>0.05).Conclusion:The PE-PLIF technique offers the benefits of reduced surgical trauma,decreased blood loss,accelerated postoperative recovery,and improved short-term restoration of lumbar function,and similar long-term efficacy to MIS-PLIF.

参考文献/References:

[1] GUO H Y,GUO M K,WAN Z Y,et al.Emerging evidence on noncoding-RNA regulatory machinery in intervertebral disc degeneration:a narrative review[J].Arthritis Research & Therapy,2020,22(1):270.
[2] VOS T,LIM S S,ABBAFATI C,et al.Global burden of 369 diseases and injuries in 204 countries and territories,1990-2019:a systematic analysis for the Global Burden of Disease Study 2019[J].The Lancet,2020,396(10258):1204-1222.
[3] XIN J G,WANG Y J,ZHENG Z,et al.Treatment of intervertebral disc degeneration[J].Orthopaedic Surgery,2022,14(7):1271-1280.
[4] BAHAR M E,HWANG J S,AHMED M,et al.Targeting autophagy for developing new therapeutic strategy in intervertebral disc degeneration[J].Antioxidants,2022,11(8):1571.
[5] FENTON-WHITE H A.Trailblazing:the historical development of the posterior lumbar interbody fusion(PLIF)[J].The Spine Journal,2021,21(9):1528-1541.
[6] HE L M,FENG H Y,MA X,et al.Percutaneous endoscopic posterior lumbar interbody fusion for the treatment of degenerative lumbar diseases:a technical note and summary of the initial clinical outcomes[J].British Journal of Neurosurgery,2024,38(3):573-578.
[7] KANG M S,YOU K H,CHOI J Y,et al.Minimally invasive transforaminal lumbar interbody fusion using the biportal endoscopic techniques versus microscopic tubular technique[J].The Spine Journal,2021,21(12):2066-2077.
[8] GE D H,STEKAS N D,VARLOTTA C G,et al.Comparative analysis of two transforaminal lumbar interbody fusion techniques:open TLIF versus wiltse MIS TLIF[J].Spine,2019,44(9):E555-E560.
[9] BADLANI N,YU E,KREITZ T,et al.Minimally invasive transforaminal lumbar interbody fusion(TLIF)[J].Clinical Spine Surgery:A Spine Publication,2020,33(2):62-64.
[10] HE L M,CHEN K T,CHEN C M,et al.Comparison of percutaneous endoscopic and open posterior lumbar interbody fusion for the treatment of single-segmental lumbar degenerative diseases[J].BMC Musculoskeletal Disorders,2022,23(1):329.
[11] NIE J W,HARTMAN T J,ZHENG E,et al.Postoperative clinical outcomes in patients undergoing MIS-TLIF versus LLIF for adjacent segment disease[J].Acta Neurochirurgica,2023,165(7):1907-1914.
[12] HEEMSKERK J L,OLUWADARA AKINDURO O,CLIFTON W,et al.Long-term clinical outcome of minimally invasive versus open single-level transforaminal lumbar interbody fusion for degenerative lumbar diseases:a meta-analysis[J].The Spine Journal,2021,21(12):2049-2065.
[13] KREINER D S,HWANG S W,EASA J E,et al.An evidence-based clinical guideline for the diagnosis and treatment of lumbar disc herniation with radiculopathy[J].The Spine Journal,2014,14(1):180-191.
[14] SORIANO SÁNCHEZ J A,SORIANO SOLÍS S,SOTO GARCÍA M E,et al.Radiological diagnostic accuracy study comparing Lenke,Bridwell,BSF,and CT-HU fusion grading scales for minimally invasive lumbar interbody fusion spine surgery and its correlation to clinical outcome[J].Medicine,2020,99(21):e19979.
[15] PRABHU M C,JACOB K C,PATEL M R,et al.History and evolution of the minimally invasive transforaminal lumbar interbody fusion[J].Neurospine,2022,19(3):479-491.
[16] JIANG C,YIN S,WEI J M,et al.Full-endoscopic posterior lumbar interbody fusion with epidural anesthesia:technical note and initial clinical experience with one-year follow-up[J].Journal of Pain Research,2021,14:3815-3826.
[17] SHEN X,ZHANG P,CHENG Q H,et al.Early result of percutaneous full-endoscopic transforaminal lumbar interbody fusion in the treatment of single-level lumbar degenerative diseases:a retrospective study[J].Neurosurgical Review,2024,47(1):115.
[18] GE M,ZHANG Y,YING H,et al.Comparison of hidden blood loss and clinical efficacy of percutaneous endoscopic transforaminal lumbar interbody fusion and minimally invasive transforaminal lumbar interbody fusion[J].International Orthopaedics,2022,46(9):2063-2070.
[19] CHEN H,ZHENG G D,BIAN Z Y,et al.Comparison of minimally invasive transforaminal lumbar interbody fusion and endoscopic lumbar interbody fusion for lumbar degenerative diseases:a retrospective observational study[J].Journal of Orthopaedic Surgery and Research,2023,18(1):389.
[20] 李珂,曹帅,张琼弛,等.腰椎融合后腰椎活动度对植入物生物力学影响的有限元分析[J].中国组织工程研究,2024,28(36):5747-5752.
[21] 葛志林,何嘉辉,程招军,等.内镜下不同入路腰椎融合术对腰椎生物力学效能影响的有限元分析[J].中国脊柱脊髓杂志,2024,34(6):620-628.
[22] SON S,YOO B R,LEE S G,et al.Full-endoscopic versus minimally invasive lumbar interbody fusion for lumbar degenerative diseases:a systematic review and meta-analysis[J].Journal of Korean Neurosurgical Society,2022,65(4):539-548.
[23] LOTAN R,LENGENOVA S,RIJINI N,et al.Intravenous tranexamic acid reduces blood loss in multilevel spine surgeries[J].The Journal of the American Academy of Orthopaedic Surgeons,2023,31(4):e226-e230.
[24] BAI J Z,ZHANG P,LIANG Y,et al.Efficacy and safety of tranexamic acid usage in patients undergoing posterior lumbar fusion:a meta-analysis[J].BMC Musculoskeletal Disorders,2019,20(1):390.
(收稿日期:2025-06-25)

备注/Memo

备注/Memo:
通信作者 E-mail:gkxf79390@sohu.com
更新日期/Last Update: 2025-11-15