[1]程森永△,方雨婷,孙海滨.加味三黄汤持续灌注治疗压力性损伤创面的临床疗效观察[J].中国中医骨伤科杂志,2025,33(11):34-39.[doi:10.20085/j.cnki.issn1005-0205.251107]
　CHENG Senyong,FANG Yuting,SUN Haibin.Clinical Efficacy of Jiawei Sanhuang Decoction in the Treatment of Pressure Injury Wounds[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2025,33(11):34-39.[doi:10.20085/j.cnki.issn1005-0205.251107]
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加味三黄汤持续灌注治疗压力性损伤创面的临床疗效观察()

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第33卷
期数:
2025年11期
页码:
34-39
栏目:
临床研究
出版日期:
2025-11-15

文章信息/Info

Title:
Clinical Efficacy of Jiawei Sanhuang Decoction in the Treatment of Pressure Injury Wounds
文章编号:
1005-0205(2025)11-0034-06
作者:
程森永1△; 方雨婷1; 孙海滨1
1南阳市中医院(独山院区)(河南 南阳,473000)
Author(s):
CHENG Senyong1△; FANG Yuting1; SUN Haibin1
1Dushan Campus,Nanyang Hospital of Traditional Chinese Medicine,Nanyang 473000,Henan China.
关键词:
压力性损伤;  创面;  三黄汤;  愈合;  中药
Keywords:
pressure injury;  wound;  Sanhuang decoction;  heal;  medicinal herb
分类号:
R641
DOI:
10.20085/j.cnki.issn1005-0205.251107
文献标志码:
A
摘要:
目的:探讨加味三黄汤持续灌注对Ⅲ/Ⅳ期压力性损伤(PI)创面愈合的影响。方法:选取Ⅲ/Ⅳ期压力性损伤患者66例,采用随机对照方法随机分为两组,观察组和对照组各33例。两组患者均行清创术后,观察组采用加味三黄汤持续灌注+负压封闭引流(VSD)治疗,对照组采用0.9%氯化钠溶液持续灌注+负压封闭引流治疗,治疗2周后采用压疮愈合评估量表(PUSH)评分、病原菌检测、创面愈合情况评定标准评定患者的临床疗效。结果:最终60例患者(观察组29例,对照组31例)完成治疗研究。术后2周PUSH评分比较,观察组优于对照组,差异有统计学意义(P<0.05); 观察组病原菌清除率高于对照组,差异有统计学意义(P<0.05); 观察组术后2周压疮面积小于对照组,差异有统计学意义(P<0.05); 创面渗液量改善两组患者差异无统计学意义(P>0.05)。结论:加味三黄汤持续灌注联合负压封闭引流较传统生理盐水冲洗方案,更能促进Ⅲ/Ⅳ期压力性损伤创面愈合,改善局部微环境,增强抗感染效果,为压力性损伤的治疗提供了新方法。
Abstract:
Objective:To investigate the effect of continuous perfusion of Jiawei Sanhuang decoction on the wound healing of stage Ⅲ/Ⅳ pressure injury.Methods:A total of 66 patients with stage Ⅲ/Ⅳ pressure injury were randomly divided into two groups with 33 in the observation group and 33 in the control group.After debridement in both groups,the observation group was treated with continuous perfusion + vacuum sealing drainage(VSD)of Jiawei Sanhuang decoction,the control group was treated with 0.9% sodium chloride solution + VSD,and the clinical efficacy of the patients was evaluated by pressure ulcer scale for healing(PUSH)score,pathogen detection and wound healing evaluation criteria after 2 weeks of treatment.Results:60 patients(29 in the observation group and 31 in the control group)were finally completed.The observation group was better than the control group(P<0.05),the pathogen removal rate in the observation group was higher than that in the control group(P<0.05),and the pressure ulcer area in the observation group was smaller than that in the control group at 2 weeks after surgery(P<0.05).There was no significant difference in the improvement trend of wound exudate(P>0.05).Conclusion:Compared with the traditional saline irrigation regimen,continuous perfusion of Jiawei Sanhuang decoction combined with VSD can promote the wound healing of stage Ⅲ/Ⅳ pressure injuries,improve the local microenvironment,and enhance the anti-infection effect,which provides a new method for the treatment of pressure injuries.

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(收稿日期:2025-04-09)

备注/Memo

备注/Memo:
基金项目:南阳市基础与前沿技术研究专项(23JCQY1010)
南阳市中医院院级课题(2023001)
△通信作者 E-mail:627265800@qq.com
更新日期/Last Update: 2025-11-15