[1]王实△,周妍,李远森.扶阳督脉灸治疗强直性脊柱炎的临床研究[J].中国中医骨伤科杂志,2025,33(11):18-23.[doi:10.20085/j.cnki.issn1005-0205.251104]
 WANG Shi,ZHOU Yan,LI Yuansen.Clinical Study on the Treatment of Ankylosing Spondylitis with Fuyang Du Mai Moxibustion[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2025,33(11):18-23.[doi:10.20085/j.cnki.issn1005-0205.251104]
点击复制

扶阳督脉灸治疗强直性脊柱炎的临床研究()

《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第33卷
期数:
2025年11期
页码:
18-23
栏目:
临床研究
出版日期:
2025-11-15

文章信息/Info

Title:
Clinical Study on the Treatment of Ankylosing Spondylitis with Fuyang Du Mai Moxibustion
文章编号:
1005-0205(2025)11-0018-06
作者:
王实1△周妍1李远森1
1广州中医药大学顺德医院(广东 佛山,528300)
Author(s):
WANG Shi1ZHOU Yan1LI Yuansen1
1Shunde Hospital of Guangzhou University of Chinese Medicine,Foshan 528300,Guangdong China.
关键词:
子午流注理论 扶阳督脉灸 强直性脊柱炎 功能状态
Keywords:
Ziwu Liuzhu theory Fuyang Du Mai moxibustion ankylosing spondylitis functional status
分类号:
R593.23
DOI:
10.20085/j.cnki.issn1005-0205.251104
文献标志码:
A
摘要:
目的:探究基于子午流注理论的扶阳督脉灸治疗强直性脊柱炎的临床疗效。方法:选择收治的肾虚督寒证型强直性脊柱炎患者120例,根据治疗方法分为对照组(58例)和子午流注组(62例),选取时间为2022年2月至2024年10月。对照组采用常规方法治疗(甲氨蝶呤片+洛索洛芬钠片),子午流注组采用基于子午流注理论的扶阳督脉灸治疗,比较两组患者的临床疗效、疼痛状况、脊柱功能状况、腰部僵痛症状、血清炎症因子水平及生活质量评估量表(SF-36)评分。结果:子午流注组患者总有效率明显高于对照组,差异有统计学意义(P<0.05)。干预后,两组患者VAS评分明显降低,子午流注组患者VAS评分明显低于对照组,差异有统计学意义(P<0.05)。干预后,子午流注组患者指地距、枕墙距、BASDAI评分、BASFI评分明显优于对照组,改良Schober试验结果明显优于对照组,差异有统计学意义(P<0.05)。干预后,两组患者腰部晨僵时间明显缩短,子午流注组腰部晨僵时间明显短于对照组; 两组患者腰部活动度明显升高,子午流注组腰部活动度明显高于对照组,差异有统计学意义(P<0.05)。干预后,两组患者C-反应蛋白(CRP)、红细胞沉降率(ESR)、肿瘤坏死因子-α(TNF-α)水平明显降低,子午流注组C-反应蛋白、红细胞沉降率、肿瘤坏死因子-α水平明显低于对照组,差异有统计学意义(P<0.05)。干预后,两组患者SF-36各项目评分均较干预前升高,且子午流注组SF-36各项目评分明显高于对照组,差异有统计学意义(P<0.05)。结论:基于子午流注理论的扶阳督脉灸对肾虚督寒证型强直性脊柱炎患者的疼痛、功能状态及炎症反应改善优于常规治疗,可提高该证型患者的生活质量。
Abstract:
Objective:Exploring the clinical efficacy of Fuyang Du Mai moxibustion treatment for ankylosing spondylitis based on the theory of Ziwu Liuzhu.Methods:120 patients with kidney deficiency and Du cold syndrome type ankylosing spondylitis were selected and divided into control group of 58 cases and Ziwu Liuzhu group of 62 cases according to the treatment method.The selection period was from February 2022 to October 2024.The control group received conventional treatment(methotrexate tablets+Loxoprofen sodium tablets),while the Ziwu Liuzhu group received Fuyang Du Mai moxibustion treatment based on the Ziwu Liuzhu theory.The clinical efficacy,pain status,spinal function,lumbar stiffness and pain symptoms,serum inflammatory factor levels,and quality of life assessment(SF-36)scale were compared between the two groups.Results:The proportion of patients with total effective rate in the Ziwu Liuzhu group was significantly higher than that in the control group(P<0.05).After intervention,the VAS scores of both groups decreased significantly,and the VAS scores of the Ziwu Liuzhu group were significantly lower than those of the control group(P<0.05).After intervention,the Ziwu Liuzhu group had significantly lower finger to ground distance,occipital wall distance,BASDAI score,and BASFI score than the control group,and the modified Schober test was significantly higher than the control group(P<0.05).After intervention,the morning stiffness time of the waist in both groups was significantly shortened.The morning stiffness time of the waist in the Ziwu Liuzhu group was significantly shorter than that in the control group,and the waist activity of both groups was significantly increased.The waist activity of the Ziwu Liuzhu group was significantly higher than that of the control group(P<0.05).After intervention,the levels of CRP,ESR,and TNF-α in both groups were significantly reduced.The levels of CRP,ESR,and TNF-α in the Ziwu Liuzhu group were significantly lower than those in the control group(P<0.05).After intervention,the scores of each SF-36 item in both groups increased compared to before intervention,and the scores of each SF-36 item in the Ziwu Liuzhu group were significantly higher than those in the control group(P<0.05).Conclusion:Based on the theory of Ziwu Liuzhu,Fuyang Du Mai moxibustion improves the pain,functional status,and inflammatory response of patients with kidney deficiency and Du cold syndrome type ankylosing spondylitis included in this study,which is superior to conventional treatment and can improve the quality of life of patients with this syndrome type.

参考文献/References:

[1] VOGAN K.Immunotherapy for ankylosing spondylitis[J].Nature Genetics,2023,55(12):2020.
[2] FAKIH O,RAMON A,CHOUK M,et al.Comparison of sacroiliac CT findings in patients with and without ankylosing spondylitis aged over 50 years[J].Scientific Reports,2023,13:17901.
[3] NAKAO Y,SAKURABA K,HARIMAYA K,et al.Clinical features and outcomes of spine surgery in patients with ankylosing spondylitis[J].Modern Rheumatology,2023,34(1):208-213.
[4] 从承志,刘健,胡月迪,等.中医药与降低强直性脊柱炎湿热证患者再入院风险相关:一项回顾性队列研究[J].中国中药杂志,2023,48(20):5651-5658.
[5] TANG X W,YANG J G,FENG Z,et al.Study of scraping with copper stone based on theory of midnight-noon ebb-flow in angina pectoris with coronary heart disease of qi stagnation and blood stasis[J].Evidence-Based Complementary and Alternative Medicine,2021:2677696.
[6] 洪秀娥,张霖云,林旺,等.基于扶阳理论督灸联合温针灸治疗阳虚寒凝型膝关节骨关节炎疗效观察[J].中国针灸,2022,42(12):1357-1362.
[7] 谢雅,杨克虎,吕青,等.强直性脊柱炎/脊柱关节炎患者实践指南[J].中华内科杂志,2020,59(7):511-518.
[8] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994.
[9] 何东仪,程鹏,汪荣盛,等.强直性脊柱炎中西医结合诊疗指南[J].上海医药,2023,44(13):23-30.
[10] LI J.Effect of warming Yang,tonifying kidney,and removing arthralgia therapy on cold-dampness arthralgia type ankylosing spondylitis and its influence on the levels of humoral factor in human serum[J].BioMed Research International,2022:8348272.
[11] WEI Y H,CHEN X F,WANG T Y,et al.Effects of du meridian moxibustion combined with mild moxibustion on female pelvic floor myofascial pain syndrome:a retrospective cohort study[J].Evidence-Based Complementary and Alternative Medicine,2022(1):7388864.
[12] 李悦,杨玉霞,闫馨月,等.基于子午流注理论运用揿针早期介入促醒重型颅脑损伤昏迷患者的临床观察[J].中华中医药杂志,2024,39(3):1582-1585.
[13] 杨淑芬,肖丽娜,刘佳,等.基于子午流注理论择时取穴中药离子导入对膝骨关节炎的疗效观察[J].护士进修杂志,2023,38(17):1604-1607.
[14] 田雨,吕智桢,陈龙豪,等.从肾督气脉论探讨腰椎间盘突出症的诊疗思路[J].浙江中医药大学学报,2024,48(9):1126-1130.
[15] 吴杰,李立国,张莹莹,等.督脉扶阳灸联合温针灸治疗阳虚寒凝证膝骨性关节炎的临床研究[J].川北医学院学报,2024,39(3):337-340.
[16] LIU Y L,WANG Y,XIE Z L,et al.Effects of the elongated needling combined with routine acupuncture therapy in the patients with post-stroke hemiplegia and central pain:a randomized controlled trial[J].Zhen Ci Yan Jiu,2024,49(3):289-295.
(收稿日期:2025-06-25)

备注/Memo

备注/Memo:
基金项目:2022年度佛山市卫生健康局医学科研项目(20220303)
通信作者 E-mail:fanjing352@163.com
更新日期/Last Update: 2025-11-15