[1]邓再冲 关宏刚△ 于淼 陈超 文磊.一期后路病灶清除植骨融合内固定术治疗单节段腰椎结核的临床疗效[J].中国中医骨伤科杂志,2019,27(09):46-49.
　DENG Zaichong GUAN Honggang YU Miao CHEN Chao WEN Lei.Clinical Efficacy of One-stage Posterior Lesion Removal and Internal Fixation in the Treatment of Single-segment Lumbar Tuberculosis[J].Chinese Journal of Traditional Medical Traumatology & Orthopedics,2019,27(09):46-49.
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一期后路病灶清除植骨融合内固定术治疗单节段腰椎结核的临床疗效()
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《中国中医骨伤科杂志》[ISSN:1005-0205/CN:42-1340/R]

卷:
第27卷
期数:
2019年09期
页码:
46-49
栏目:
临床论著
出版日期:
2019-09-08

文章信息/Info

Title:
Clinical Efficacy of One-stage Posterior Lesion Removal and Internal Fixation in the Treatment of Single-segment Lumbar Tuberculosis
文章编号:
1005-0205(2019)09-0046-04
作者:
邓再冲1 关宏刚1△ 于淼1 陈超1 文磊1
1广州中医药大学附属佛山中医院(广东 佛山,528000)
Author(s):
DENG Zaichong1 GUAN Honggang1△ YU Miao1 CHEN Chao1 WEN Lei1
1Foshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine,Foshan 528000,Guangdong China.
关键词:
腰椎;  结核;  病灶清除;  内固定;  融合
Keywords:
lumbar spine;  tuberculosis(TB);  lesion removal;  internal fixation;  fusion
分类号:
R681.5
文献标志码:
A
摘要:
目的:回顾性分析一期后路病灶清除植骨融合内固定术治疗单节段腰椎结核的临床疗效和安全性。方法:回顾分析2008年1月至2018年1月在本科手术治疗的18例单节段腰椎结核患者的临床资料,通过血沉(ESR)、C反应蛋白(CRP)、视觉模拟评分(VAS)、腰椎JOA评分(JOA)、病变节段后凸Cobb角和术后并发症等指标分析手术疗效及安全性。结果:所有患者术后末次随访的ESR,CRP,VAS及JOA与术前对比的差异均有统计学意义(P<0.001),所有患者末次随访时病灶均获得骨性融合。术前病变节段矢状面Cobb角10.36°±4.26°,术后矫正至5.06°±2.11°,末次随访时为5.67°±1.95°,早期矫正率73.0%±20.1%,矫正丢失度为3.22°±1.04°.1例患者术后1年内出现内固定松动,但无断裂,其余患者未出现内固定松动、断裂等并发症。结论:在合理规范应用抗结核药物治疗的基础上,一期后路病灶清除植骨融合内固定术是治疗单节段腰椎结核的一种有效、安全的方法。
Abstract:
Objective:To retrospectively analyze the clinical efficacy and safety of one-stage posterior approach bone graft fusion and internal fixation for the treatment of single-segment lumbar tuberculosis.Methods:Retrospective analysis in January 2008 to January 2018 in our department of surgical treatment of 18 cases of patients with single segmental lumbar tuberculosis clinical data,through the blood sedimentation(ESR),c-reactive protein(CRP)and visual analogue scale(VAS)and lumbar JOA score(JOA),the pathological changes after segmental convex Cobb Angle and the postoperative complications such as index analysis operation efficacy and safety.Results:The difference of ESR,CRP,VAS,JOA in the last postoperative follow-up between all patients and the preoperative comparison was statistically significant(P<0.001).Bone fusion was achieved in all patients at the last follow-up.The Cobb angle 10.36°±4.26° in the sagittal plane of the lesion segment before surgery was corrected to 5.06°±2.11° after surgery,and 5.67°±1.95° at the last follow-up,with an early correction rate 73.0%±20.1% and a correction loss rate 3.22°±1.04°.Within 1 year after surgery,loose internal fixation occurred in 1 patient,but no fracture occurred,and other complications such as loose internal fixation and fracture did not occur in the other patients.Conclusion:On the basis of reasonable and standard application of anti-tuberculosis drugs,one-stage posterior approach bone graft fusion and internal fixation is an effective and safe method for the treatment of single-segment lumbar tuberculosis.

参考文献/References:

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备注/Memo

备注/Memo:
△通信作者 E-mail:fshg@163.com(收稿日期:2019-04-02)
更新日期/Last Update: 2019-09-08